| Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis SA Berghoff, L Spieth, T Sun, L Hosang, L Schlaphoff, C Depp, T Düking, ... Nature neuroscience 24 (1), 47-60, 2021 | 197 | 2021 |
| Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease C Depp, T Sun, AO Sasmita, L Spieth, SA Berghoff, T Nazarenko, ... Nature 618 (7964), 349-357, 2023 | 131 | 2023 |
| Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model SA Berghoff, T Düking, L Spieth, J Winchenbach, SK Stumpf, N Gerndt, ... Acta Neuropathologica Communications 5, 1-13, 2017 | 81 | 2017 |
| Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease SK Stumpf, SA Berghoff, A Trevisiol, L Spieth, T Düking, LV Schneider, ... Acta neuropathologica 138, 147-161, 2019 | 70 | 2019 |
| Local cholesterol metabolism orchestrates remyelination SA Berghoff, L Spieth, G Saher Trends in Neurosciences 45 (4), 272-283, 2022 | 51 | 2022 |
| Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice SA Berghoff, L Spieth, T Sun, L Hosang, C Depp, AO Sasmita, ... Cell Reports 37 (4), 2021 | 39 | 2021 |
| Ketogenic diet uncovers differential metabolic plasticity of brain cells T Düking, L Spieth, SA Berghoff, L Piepkorn, AM Schmidke, M Mitkovski, ... Science advances 8 (37), eabo7639, 2022 | 33 | 2022 |
| Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport L Spieth, SA Berghoff, SK Stumpf, J Winchenbach, T Michaelis, ... Neuro-oncology advances 3 (1), vdab140, 2021 | 18 | 2021 |
| Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease C Depp, T Sun, AO Sasmita, L Spieth, SA Berghoff, AA Steixner-Kumar, ... Biorxiv, 2021.07. 31.454562, 2021 | 17 | 2021 |
| NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance S Arinrad, JBH Wilke, A Seelbach, J Doeren, M Hindermann, UJ Butt, ... Molecular Psychiatry 27 (12), 4974-4983, 2022 | 13 | 2022 |
| Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis S Kalinin, GP Meares, SX Lin, EA Pietruczyk, G Saher, L Spieth, KA Nave, ... Glia 68 (3), 600-616, 2020 | 12 | 2020 |
| Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer's disease AO Sasmita, C Depp, T Nazarenko, T Sun, SB Siems, X Yu, C Boehler, ... bioRxiv, 2023.12. 11.570514, 2023 | 3 | 2023 |
| T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis S Kedia, H Ji, R Feng, P Androvic, L Spieth, L Liu, J Franz, H Zdiarstek, ... Nature neuroscience 27 (8), 1468-1474, 2024 | 2 | 2024 |
| Nedd4-2-dependent regulation of astrocytic Kir4. 1 and Connexin43 controls neuronal network activity B Altas, HJ Rhee, A Ju, HC Solís, S Karaca, J Winchenbach, ... Journal of Cell Biology 223 (1), 2024 | 1 | 2024 |
| Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin M Reich, MJ Simon, B Polke, G Werner, C Schrader, I Paris, S Robinson, ... bioRxiv, 2023.07. 14.549089, 2023 | 1 | 2023 |
| Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer’s disease L Spieth, M Simons PLoS biology 22 (9), e3002798, 2024 | | 2024 |
| Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice AO Sasmita, C Depp, T Nazarenko, T Sun, SB Siems, EC Ong, YB Nkeh, ... Nature neuroscience, 1-7, 2024 | | 2024 |
| Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration M Reich, MJ Simon, B Polke, I Paris, G Werner, C Schrader, L Spieth, ... Science translational medicine 16 (750), eadj7308, 2024 | | 2024 |
| Activity-dependent regulation of vascular cholesterol metabolism acts as a negative feedback mechanism for neurovascular coupling CP Profaci, KL Foreman, L Spieth, V Coelho-Santos, SA Berghoff, ... bioRxiv, 2024.02. 23.581685, 2024 | | 2024 |
| Ablation of cell-specific cholesterol synthesis affects cerebral β-amyloidosis L Spieth | | 2023 |
