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N Ajenjo
N Ajenjo
在 cnio.es 的电子邮件经过验证
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引用次数
引用次数
年份
p38α MAP kinase as a sensor of reactive oxygen species in tumorigenesis
I Dolado, A Swat, N Ajenjo, G De Vita, A Cuadrado, AR Nebreda
Cancer cell 11 (2), 191-205, 2007
4962007
Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition
C Blanco-Aparicio, AMG Collazo, J Oyarzabal, JF Leal, MI Albarán, ...
Cancer letters 300 (2), 145-153, 2011
672011
Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway
JP Vaqué, J Navascues, Y Shiio, M Laiho, N Ajenjo, I Mauleon, ...
Journal of Biological Chemistry 280 (2), 1112-1122, 2005
552005
The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF
I Arozarena, DS Aaronson, D Matallanas, V Sanz, N Ajenjo, SP Tenbaum, ...
Journal of Biological Chemistry 275 (34), 26441-26448, 2000
542000
Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation
N Ajenjo, DS Aaronson, E Ceballos, C Richard, J León, P Crespo
Journal of Biological Chemistry 275 (10), 7189-7197, 2000
482000
Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does …
A Lerga, P Crespo, M Berciano, MD Delgado, M Canelles, C Cales, ...
351999
Discovery of novel triazolo [4, 3-b] pyridazin-3-yl-quinoline derivatives as PIM inhibitors
S Martinez-Gonzalez, S Rodriguez-Aristegui, CAG de la Oliva, ...
European Journal of Medicinal Chemistry 168, 87-109, 2019
302019
A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis
L Zhu, D Retana, P García‐Gómez, L Álvaro‐Espinosa, N Priego, ...
EMBO Molecular Medicine 14 (3), e14552, 2022
122022
Macrocyclization as a source of desired polypharmacology. Discovery of triple PI3K/mTOR/PIM inhibitors
S Martínez-González, RM Alvarez, JI Martín, AB García, ...
ACS Medicinal Chemistry Letters 12 (11), 1794-1801, 2021
102021
Determination of viability of human cartilage allografts by a rapid and quantitative method not requiring cartilage digestion
C López, N Ajenjo, MJ Muñoz-Alonso, P Farde, J León, J Gómez-Cimiano
Cell Transplantation 17 (7), 859-864, 2008
102008
Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits
A Sanchez-Aguilera, M Masmudi-Martín, A Navas-Olive, P Baena, ...
Cancer Cell 41 (9), 1637-1649. e11, 2023
62023
Public-Private Partnerships in Biobanking: Current Practices
MM Morente, F de Luna, MC Marin, N Ajenjo
Advances in Biobanking Practice through Public and Private Collaborations, 1-11, 2017
22017
Co-targeting PIM and PI3K/mTOR pathways with a single molecule: Novel orally available combined PIM/PI3K and PIM/PI3K/mTOR kinase inhibitors.
C Blanco Aparicio, O Renner, E Gomez-Casero, A Cebria, N Ajenjo, ...
MOLECULAR CANCER THERAPEUTICS 12 (11), 2013
22013
National biobank networking: the case of Spain
MM Morente, F Luna-Crespo, N Ajenjo, MJ Artiga, E Ortega-Paino
Biobanking of Human Biospecimens: Lessons from 25 Years of Biobanking …, 2021
12021
Abstract A275: Co-targeting PIM and PI3K/mTOR pathways with a single molecule: Novel orally available combined PIM/PI3K and PIM/PI3K/mTOR kinase inhibitors.
C Blanco Aparicio, O Renner, E Gomez-Casero, A Cebriá, N Ajenjo, ...
Molecular Cancer Therapeutics 12 (11_Supplement), A275-A275, 2013
12013
Abstract B228: Discovery of 6-Methyl-3-aryl-7, 8-dihydro-6H-9-oxa-1, 2, 3a, 4, 6-pentaaza-cyclopenta [a] naphthalen-5-ylamine compounds as Pim kinase inhibitors with potent …
CB Aparicio, S Martinez, B Garcia-Serelde, AM Garcia-Collazo, N Ajenjo, ...
Molecular Cancer Therapeutics 10 (11_Supplement), B228-B228, 2011
2011
54 Biological characterization of ETP-45299, a selective small molecule inhibitor of PIM1, in human tumor cell lines
CB Aparicio, AG Collazo, FR Lima, N Ajenjo, I Palacios, H Quiñones, ...
Ejc Supplements 7 (8), 26, 2010
2010
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY-Subcellular Localization Determines the Protective Effects of Activated ERK2 against Distinct Apoptogenic Stimuli in Myeloid …
N Ajenjo, E Canon, I Sanchez-Perez, D Matallanas, J Leon, R Perona, ...
Journal of Biological Chemistry 279 (31), 32813-32823, 2004
2004
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY-Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation
N Ajenjo, DS Aaronson, E Ceballos, C Richard, J Leon, P Crespo
Journal of Biological Chemistry 275 (10), 7189-7197, 2000
2000
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