Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway X Lojewski, JF Staropoli, S Biswas-Legrand, AM Simas, L Haliw, MK Selig, ... Human molecular genetics 23 (8), 2005-2022, 2014 | 148 | 2014 |
Unbiased cell-based screening in a neuronal cell model of Batten disease highlights an interaction between Ca2+ homeostasis, autophagy, and CLN3 protein function U Chandrachud, MW Walker, AM Simas, S Heetveld, A Petcherski, ... Journal of Biological Chemistry 290 (23), 14361-14380, 2015 | 93 | 2015 |
The CLN3 gene and protein: What we know M Mirza, A Vainshtein, A DiRonza, U Chandrachud, LJ Haslett, M Palmieri, ... Molecular genetics & genomic medicine 7 (12), e859, 2019 | 57 | 2019 |
Moving towards a new era of genomics in the neuronal ceroid lipofuscinoses ES Butz, U Chandrachud, SE Mole, SL Cotman Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (9), 165571, 2020 | 56 | 2020 |
Assembly− Disassembly of DNAs and Gold Nanoparticles: A Strategy of Intervention Based on Oligonucleotides and Restriction Enzymes IIS Lim, U Chandrachud, L Wang, S Gal, CJ Zhong Analytical chemistry 80 (15), 6038-6044, 2008 | 47 | 2008 |
An autophagy modifier screen identifies small molecules capable of reducing autophagosome accumulation in a model of CLN3-mediated neurodegeneration A Petcherski, U Chandrachud, ES Butz, MC Klein, WN Zhao, SA Reis, ... Cells 8 (12), 1531, 2019 | 14 | 2019 |
Three assays show differences in binding of wild-type and mutant p53 to unique gene sequences U Chandrachud, S Gal Technology in cancer research & treatment 8 (6), 445-453, 2009 | 12 | 2009 |
Scintillation proximity assay for total p53 protein as an alternative to ELISA S Oberlander, T Xie, U Chandrachud, S Gal Journal of immunological methods 360 (1-2), 173-177, 2010 | 7 | 2010 |
Assembly/Disassembly of DNA‐Au Nanoparticles: A Strategy of Intervention IIS Lim, L Wang, U Chandrachud, S Gal, CJ Zhong Journal of Nanotechnology 2008 (1), 527294, 2008 | 3 | 2008 |
Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover S Yasa, E Butz, A Colombo, U Chandrachud, L Montore, S Sheridan, ... bioRxiv, 2024.02. 01.578018, 2024 | | 2024 |
BIOT 399-Assembly and disassembly of DNA-gold nanoprobes S Lim, L Wang, U Chandrachud, M Kamundi, R Loukrakpam, S Gal, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 236, 2008 | | 2008 |