Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10770 | 2021 |
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer PJ Roberts, CJ Der Oncogene 26 (22), 3291-3310, 2007 | 3498 | 2007 |
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ... Autophagy 4 (2), 151-175, 2008 | 2732 | 2008 |
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors KL Rossman, CJ Der, J Sondek Nature reviews Molecular cell biology 6 (2), 167-180, 2005 | 2156 | 2005 |
The Ras superfamily at a glance K Wennerberg, KL Rossman, CJ Der Journal of cell science 118 (5), 843-846, 2005 | 2083 | 2005 |
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts K Irani, Y Xia, JL Zweier, SJ Sollott, CJ Der, ER Fearon, M Sundaresan, ... Science 275 (5306), 1649-1652, 1997 | 2029 | 1997 |
Drugging the undruggable RAS: Mission possible? AD Cox, SW Fesik, AC Kimmelman, J Luo, CJ Der Nature reviews Drug discovery 13 (11), 828-851, 2014 | 2020 | 2014 |
Increasing complexity of Ras signaling SL Campbell, R Khosravi-Far, KL Rossman, GJ Clark, CJ Der Oncogene 17 (11), 1395-1413, 1998 | 1475 | 1998 |
p21ras is modified by a farnesyl isoprenoid. PJ Casey, PA Solski, CJ Der, JE Buss Proceedings of the National Academy of Sciences 86 (21), 8323-8327, 1989 | 1205 | 1989 |
Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses. CJ Der, TG Krontiris, GM Cooper Proceedings of the National Academy of Sciences 79 (11), 3637-3640, 1982 | 1159 | 1982 |
Understanding Ras:‘it ain’t over’til it’s over’ JM Shields, K Pruitt, A McFall, A Shaub, CJ Der Trends in cell biology 10 (4), 147-154, 2000 | 1083 | 2000 |
RAS isoforms and mutations in cancer at a glance GA Hobbs, CJ Der, KL Rossman Journal of cell science 129 (7), 1287-1292, 2016 | 975 | 2016 |
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy? D Vigil, J Cherfils, KL Rossman, CJ Der Nature Reviews Cancer 10 (12), 842-857, 2010 | 969 | 2010 |
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI (3) K PJ Keely, JK Westwick, IP Whitehead, CJ Der, LV Parise Nature 390 (6660), 632-636, 1997 | 915 | 1997 |
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation R Khosravi-Far, PA Solski, GJ Clark, MS Kinch, CJ Der Molecular and cellular biology, 1995 | 906 | 1995 |
BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein AM Pendergast, LA Quilliam, LD Cripe, CH Bassing, Z Dai, N Li, A Batzer, ... Cell 75 (1), 175-185, 1993 | 906 | 1993 |
Ras history: The saga continues AD Cox, CJ Der Small GTPases 1 (1), 2-27, 2010 | 865 | 2010 |
Rho-family GTPases: it's not only Rac and Rho (and I like it) K Wennerberg, CJ Der Journal of cell science 117 (8), 1301-1312, 2004 | 862 | 2004 |
Increasing complexity of the Ras signaling pathway AB Vojtek, CJ Der Journal of Biological Chemistry 273 (32), 19925-19928, 1998 | 814 | 1998 |
KRAS: the critical driver and therapeutic target for pancreatic cancer AM Waters, CJ Der Cold Spring Harbor perspectives in medicine 8 (9), a031435, 2018 | 813 | 2018 |