| Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape SR Woo, ME Turnis, MV Goldberg, J Bankoti, M Selby, CJ Nirschl, ... Cancer research 72 (4), 917-927, 2012 | 1765 | 2012 |
| Stereotactic radiation therapy augments antigen-specific PD-1–mediated antitumor immune responses via cross-presentation of tumor antigen AB Sharabi, CJ Nirschl, CM Kochel, TR Nirschl, BJ Francica, E Velarde, ... Cancer immunology research 3 (4), 345-355, 2015 | 627 | 2015 |
| Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia F McAllister, JM Bailey, J Alsina, CJ Nirschl, R Sharma, H Fan, Y Rattigan, ... Cancer cell 25 (5), 621-637, 2014 | 404 | 2014 |
| Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy CJ Nirschl, CG Drake Clinical cancer research 19 (18), 4917-4924, 2013 | 385 | 2013 |
| Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance AM Martin, TR Nirschl, CJ Nirschl, BJ Francica, CM Kochel, ... Prostate cancer and prostatic diseases 18 (4), 325-332, 2015 | 207 | 2015 |
| Phenotypic and functional properties of Helios+ regulatory T cells DJ Zabransky, CJ Nirschl, NM Durham, BV Park, CM Ceccato, TC Bruno, ... PloS one 7 (3), e34547, 2012 | 189 | 2012 |
| Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivo NM Durham, CJ Nirschl, CM Jackson, J Elias, CM Kochel, RA Anders, ... PloS one 9 (11), e109080, 2014 | 182 | 2014 |
| IFNγ-dependent tissue-immune homeostasis is co-opted in the tumor microenvironment CJ Nirschl, M Suárez-Fariñas, B Izar, S Prakadan, R Dannenfelser, ... Cell 170 (1), 127-141. e15, 2017 | 152 | 2017 |
| Sustained CD4+ T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide S Ellsworth, A Balmanoukian, F Kos, CJ Nirschl, TR Nirschl, SA Grossman, ... Oncoimmunology 3 (1), e27357, 2014 | 72 | 2014 |
| Systemic tolerance mediated by melanoma brain tumors is reversible by radiotherapy and vaccination CM Jackson, CM Kochel, CJ Nirschl, NM Durham, J Ruzevick, A Alme, ... Clinical Cancer Research 22 (5), 1161-1172, 2016 | 71 | 2016 |
| PD-L1 expression in medulloblastoma: An evaluation by subgroup AM Martin, CJ Nirschl, MJ Polanczyk, WR Bell, TR Nirschl, ... Oncotarget 9 (27), 19177, 2018 | 57 | 2018 |
| An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes A Jaiswal, A Verma, R Dannenfelser, M Melssen, I Tirosh, B Izar, TG Kim, ... Cancer Cell 40 (5), 524-544. e5, 2022 | 37 | 2022 |
| Discovery of a conditionally activated IL-2 that promotes antitumor immunity and induces tumor regression CJ Nirschl, HR Brodkin, DJ Hicklin, N Ismail, K Morris, C Seidel-Dugan, ... Cancer immunology research 10 (5), 581-596, 2022 | 35 | 2022 |
| Sorafenib combined with HER-2 targeted vaccination can promote effective T cell immunity in vivo MME Sunay, JB Foote, JM Leatherman, JP Edwards, TD Armstrong, ... International immunopharmacology 46, 112-123, 2017 | 32 | 2017 |
| PPARγ contributes to immunity induced by cancer cell vaccines that secrete GM-CSF G Goyal, K Wong, CJ Nirschl, N Souders, D Neuberg, ... Cancer immunology research 6 (6), 723-732, 2018 | 27 | 2018 |
| Near-infrared 1064 nm laser modulates migratory dendritic cells to augment the immune response to intradermal influenza vaccine K Morse, Y Kimizuka, MPK Chan, M Shibata, Y Shimaoka, S Takeuchi, ... The Journal of Immunology 199 (4), 1319-1332, 2017 | 27 | 2017 |
| Duality at the gate: skin dendritic cells as mediators of vaccine immunity and tolerance CJ Nirschl, N Anandasabapathy Human Vaccines & Immunotherapeutics 12 (1), 104-116, 2016 | 12 | 2016 |
| Role of radiation therapy in inducing antigen specific antitumor immune responses when combined with anti-PD1 checkpoint blockade: Mechanism and clinical implications A Sharabi, C Nirschl, T Ceccato, T Nirschl, B Francica, A Alme, E Velarde, ... International Journal of Radiation Oncology, Biology, Physics 90 (1), S1, 2014 | 9 | 2014 |
| Characterization of ASP8374, a fully-human, antagonistic anti-TIGIT monoclonal antibody K Shirasuna, G Koelsch, C Seidel-Dugan, A Salmeron, P Steiner, ... Cancer Treatment and Research Communications 28, 100433, 2021 | 7 | 2021 |
| Conditionally activated IL-12 or IFNα indukine™ molecules inhibit syngeneic lymphoma tumor growth in mice, induce anti-tumor immune responses and are tolerated in non-human … P Steiner, H Brodkin, J Canales, D Hicklin, R Isaacs, N Ismail, K Morris, ... Blood 138, 2258, 2021 | 6 | 2021 |
Charles G. DrakeImmunology在 jhmi.edu 的电子邮件经过验证
