| The human intestinal cytochrome P450 “pie” MF Paine, HL Hart, SS Ludington, RL Haining, AE Rettie, DC Zeldin Drug metabolism and disposition 34 (5), 880-886, 2006 | 1041 | 2006 |
| Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism MF Paine, M Khalighi, JM Fisher, DD Shen, KL Kunze, CL Marsh, ... Journal of Pharmacology and Experimental Therapeutics 283 (3), 1552-1562, 1997 | 1030 | 1997 |
| Oral first‐pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A‐mediated metabolism KE Thummel, D O'Shea, MF Paine, DD Shen, KL Kunze, JD Perkins, ... Clinical Pharmacology & Therapeutics 59 (5), 491-502, 1996 | 728 | 1996 |
| First‐pass metabolism of midazolam by the human intestine MF Paine, DD Shen, KL Kunze, JD Perkins, CL Marsh, JP McVicar, ... Clinical Pharmacology & Therapeutics 60 (1), 14-24, 1996 | 635 | 1996 |
| The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism*† MB Fisher, MF Paine, TJ Strelevitz, SA Wrighton Drug metabolism reviews 33 (3-4), 273-297, 2001 | 441 | 2001 |
| Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1α, 25-dihydroxyvitamin D3 P Schmiedlin-Ren, KE Thummel, JM Fisher, MF Paine, KS Lown, ... Molecular pharmacology 51 (5), 741-754, 1997 | 436 | 1997 |
| Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions RB Labroo, MF Paine, KE Thummel, ED Kharasch Drug Metabolism and Disposition 25 (9), 1072-1080, 1997 | 395 | 1997 |
| P-glycoprotein increases from proximal to distal regions of human small intestine S Mouly, MF Paine Pharmaceutical research 20, 1595-1599, 2003 | 344 | 2003 |
| Molecular and physical mechanisms of first-pass extraction SD Hall, KE Thummel, PB Watkins, KS Lown, LZ Benet, MF Paine, ... Drug Metabolism and Disposition 27 (2), 161-166, 1999 | 343 | 1999 |
| Seville orange juice‐felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins S Malhotra, DG Bailey, MF Paine, PB Watkins Clinical Pharmacology & Therapeutics 69 (1), 14-23, 2001 | 294 | 2001 |
| A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice–felodipine interaction MF Paine, WW Widmer, HL Hart, SN Pusek, KL Beavers, AB Criss, ... The American journal of clinical nutrition 83 (5), 1097-1105, 2006 | 219 | 2006 |
| Herb–drug interactions: challenges and opportunities for improved predictions SJ Brantley, AA Argikar, YS Lin, S Nagar, MF Paine Drug Metabolism and Disposition 42 (3), 301-317, 2014 | 213 | 2014 |
| Mechanisms underlying food–drug interactions: inhibition of intestinal metabolism and transport CS Won, NH Oberlies, MF Paine Pharmacology & therapeutics 136 (2), 186-201, 2012 | 190 | 2012 |
| Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers RJ Fontana, KS Lown, MF Paine, L Fortlage, RM Santella, JS Felton, ... Gastroenterology 117 (1), 89-98, 1999 | 185 | 1999 |
| United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts HA Oketch-Rabah, AL Roe, CV Rider, HL Bonkovsky, GI Giancaspro, ... Toxicology reports 7, 386-402, 2020 | 155 | 2020 |
| Diamidines for human African trypanosomiasis WD Wilson, HP De Koningº, CA Olson, G Pohlig Current Opinion in Investigational Drugs 11 (8), 876-883, 2010 | 148 | 2010 |
| Breast cancer resistance protein (ABCG2) in clinical pharmacokinetics and drug interactions: practical recommendations for clinical victim and perpetrator drug-drug interaction … CA Lee, MA O’Connor, TK Ritchie, A Galetin, JA Cook, ... Drug Metabolism and Disposition 43 (4), 490-509, 2015 | 147 | 2015 |
| Induction of CYP3A4 by 1α, 25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor P Schmiedlin-Ren, KE Thummel, JM Fisher, MF Paine, PB Watkins Drug Metabolism and Disposition 29 (11), 1446-1453, 2001 | 142 | 2001 |
| Cytochrome P-450 1A1 expression in human small bowel: interindividual variation and inhibition by ketoconazole MF Paine, P Schmiedlin-Ren, PB Watkins Drug metabolism and disposition 27 (3), 360-364, 1999 | 134 | 1999 |
| Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition MF Paine, AB Criss, PB Watkins Journal of Pharmacology and Experimental Therapeutics 312 (3), 1151-1160, 2005 | 133 | 2005 |
