| Sphingosine‐1‐phosphate receptor 2 M Adada, D Canals, YA Hannun, LM Obeid The FEBS journal 280 (24), 6354-6366, 2013 | 170 | 2013 |
| Inhibitors of the sphingomyelin cycle: Sphingomyelin synthases and sphingomyelinases M Adada, C Luberto, D Canals Chemistry and physics of lipids 197, 45-59, 2016 | 130 | 2016 |
| Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma R Sakemura, M Hefazi, EL Siegler, MJ Cox, DP Larson, MJ Hansen, ... Blood, The Journal of the American Society of Hematology 139 (26), 3708-3721, 2022 | 93 | 2022 |
| Intracellular sphingosine kinase 2–derived sphingosine-1-phosphate mediates epidermal growth factor–induced ezrin-radixin-moesin phosphorylation and cancer cell invasion MM Adada, D Canals, N Jeong, AD Kelkar, M Hernandez-Corbacho, ... The FASEB Journal 29 (11), 4654, 2015 | 83 | 2015 |
| Sphingolipid regulation of ezrin, radixin, and moesin proteins family: implications for cell dynamics M Adada, D Canals, YA Hannun, LM Obeid Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 80 | 2014 |
| Tumor necrosis factor-α (TNFα)-induced ceramide generation via ceramide synthases regulates loss of focal adhesion kinase (FAK) and programmed cell death MJ Hernández-Corbacho, D Canals, MM Adada, M Liu, CE Senkal, JK Yi, ... Journal of Biological Chemistry 290 (42), 25356-25373, 2015 | 73 | 2015 |
| P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment M Wada, D Canals, M Adada, N Coant, MF Salama, KL Helke, JS Arthur, ... Oncogene 36 (47), 6649-6657, 2017 | 72 | 2017 |
| Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia MJ Cox, F Lucien, R Sakemura, JC Boysen, Y Kim, P Horvei, CM Roman, ... Molecular Therapy 29 (4), 1529-1540, 2021 | 71 | 2021 |
| Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins KAO Gandy, D Canals, M Adada, M Wada, P Roddy, AJ Snider, ... Biochemical Journal 449 (3), 661-672, 2013 | 71 | 2013 |
| Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor κB activation MM Adada, KA Orr-Gandy, AJ Snider, D Canals, YA Hannun, LM Obeid, ... Journal of Biological Chemistry 288 (38), 27667-27679, 2013 | 59 | 2013 |
| A novel role of sphingosine kinase-1 in the invasion and angiogenesis of VHL mutant clear cell renal cell carcinoma MF Salama, B Carroll, M Adada, M Pulkoski-Gross, YA Hannun, LM Obeid The FASEB Journal 29 (7), 2803, 2015 | 58 | 2015 |
| Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation KAO Gandy, M Adada, D Canals, B Carroll, P Roddy, YA Hannun, ... The FASEB Journal 27 (8), 3155, 2013 | 42 | 2013 |
| Ceramide and sphingosine-1-phosphate in cancer, two faces of the sphinx MP Espaillat, AA Shamseddine, MM Adada, YA Hannun, LM Obeid Translational Cancer Research 4 (5), 2015 | 38 | 2015 |
| Ceramide launches an acute anti‐adhesion pro‐migration cell signaling program in response to chemotherapy D Canals, S Salamone, BJ Santacreu, E Nemeth, D Aguilar, ... The FASEB journal 34 (6), 7610-7630, 2020 | 32 | 2020 |
| Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway DM Perry, B Newcomb, M Adada, BX Wu, P Roddy, K Kitatani, L Siskind, ... Journal of Biological Chemistry 289 (32), 22401-22412, 2014 | 30 | 2014 |
| Development of a clinically relevant reporter for chimeric antigen receptor T-cell expansion, trafficking, and toxicity R Sakemura, A Bansal, EL Siegler, M Hefazi, N Yang, RH Khadka, ... Cancer immunology research 9 (9), 1035-1046, 2021 | 25 | 2021 |
| GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity MJ Cox, C Manriquez Roman, EE Tapper, EL Siegler, D Chappell, ... Leukemia 36 (6), 1635-1645, 2022 | 21 | 2022 |
| Sustained PKCβII activity confers oncogenic properties in a phospholipase D-and mTOR-dependent manner M El Osta, M Liu, M Adada, CE Senkal, J Idkowiak-Baldys, LM Obeid, ... The FASEB Journal 28 (1), 495, 2014 | 17 | 2014 |
| CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS RL Sakemura, C Manriquez Roman, P Horvei, EL Siegler, JH Girsch, ... Blood 143 (3), 258-271, 2024 | 10 | 2024 |
| Assessment of chimeric antigen receptor T cell-associated toxicities using an acute lymphoblastic leukemia patient-derived xenograft mouse model CM Roman, RL Sakemura, BL Kimball, F Jin, RH Khadka, MM Adada, ... JoVE (Journal of Visualized Experiments), e64535, 2023 | 6 | 2023 |
