| Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum LH Freitas-Junior, E Bottius, LA Pirrit, KW Deitsch, C Scheidig, F Guinet, ... Nature 407 (6807), 1018-1022, 2000 | 621 | 2000 |
| Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites LH Freitas-Junior, R Hernandez-Rivas, SA Ralph, D Montiel-Condado, ... Cell 121 (1), 25-36, 2005 | 570 | 2005 |
| Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum MT Duraisingh, TS Voss, AJ Marty, MF Duffy, RT Good, JK Thompson, ... Cell 121 (1), 13-24, 2005 | 541 | 2005 |
| In vitro and in vivo experimental models for drug screening and development for Chagas disease AJ Romanha, SL Castro, MNC Soeiro, J Lannes-Vieira, I Ribeiro, ... Memórias do Instituto Oswaldo Cruz 105, 233-238, 2010 | 394 | 2010 |
| Visceral leishmaniasis treatment: what do we have, what do we need and how to deliver it? LH Freitas-Junior, E Chatelain, HA Kim, JL Siqueira-Neto International Journal for Parasitology: Drugs and Drug Resistance 2, 11-19, 2012 | 370 | 2012 |
| Multitarget drug discovery for tuberculosis and other infectious diseases K Li, LA Schurig-Briccio, X Feng, A Upadhyay, V Pujari, B Lechartier, ... Journal of medicinal chemistry 57 (7), 3126-3139, 2014 | 255 | 2014 |
| The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles A Acosta-Serrano, IC Almeida, LH Freitas-Junior, N Yoshida, ... Molecular and biochemical parasitology 114 (2), 143-150, 2001 | 254 | 2001 |
| Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and … CB Moraes, MA Giardini, H Kim, CH Franco, AM Araujo-Junior, ... Scientific reports 4 (1), 4703, 2014 | 226 | 2014 |
| An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages JL Siqueira-Neto, S Moon, J Jang, G Yang, C Lee, HK Moon, E Chatelain, ... PLoS neglected tropical diseases 6 (6), e1671, 2012 | 175 | 2012 |
| Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds JL Siqueira-Neto, OR Song, H Oh, JH Sohn, G Yang, J Nam, J Jang, ... PLoS neglected tropical diseases 4 (5), e675, 2010 | 174 | 2010 |
| A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation LM Figueiredo, LH Freitas‐Junior, E Bottius, JC Olivo‐Marin, A Scherf The EMBO journal, 2002 | 163 | 2002 |
| A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes RA O'Donnell, LH Freitas‐Junior, PR Preiser, DH Williamson, ... The EMBO journal, 2002 | 161 | 2002 |
| Plasmodium telomeres: a pathogen's perspective A Scherf, LM Figueiredo, LH Freitas-Junior Current opinion in microbiology 4 (4), 409-414, 2001 | 150 | 2001 |
| Biochemical characterization of proline racemases from the human protozoan parasite Trypanosoma cruzi and definition of putative protein signatures N Chamond, C Grégoire, N Coatnoan, C Rougeot, LH Freitas-Junior, ... Journal of Biological Chemistry 278 (18), 15484-15494, 2003 | 92 | 2003 |
| UV-C (254 nm) lethal doses for SARS-CoV-2 CP Sabino, FP Sellera, DF Sales-Medina, RRG Machado, EL Durigon, ... Photodiagnosis and Photodynamic Therapy 32, 101995, 2020 | 86 | 2020 |
| An image analysis algorithm for malaria parasite stage classification and viability quantification S Moon, S Lee, H Kim, LH Freitas-Junior, M Kang, L Ayong, MAE Hansen PloS one 8 (4), e61812, 2013 | 84 | 2013 |
| Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library BS Pascoalino, G Courtemanche, MT Cordeiro, LHVG Gil, ... F1000Research 5, 2016 | 80 | 2016 |
| Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library DJM Cruz, RM Bonotto, RGB Gomes, CT da Silva, JB Taniguchi, JH No, ... PLoS neglected tropical diseases 7 (10), e2471, 2013 | 80 | 2013 |
| Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity JH No, F de Macedo Dossin, Y Zhang, YL Liu, W Zhu, X Feng, JA Yoo, ... Proceedings of the National Academy of Sciences 109 (11), 4058-4063, 2012 | 76 | 2012 |
| Possible integration of Trypanosoma cruzi kDNA minicircles into the host cell genome by infection ARL Teixeira, ER Argañaraz, LH Freitas Jr, ZGM Lacava, JM Santana, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 305 (2 …, 1994 | 74 | 1994 |
Carolina Borsoi MoraesDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of在 usp.br 的电子邮件经过验证
