Influence of protein fold stability on immunogenicity and its implications for vaccine design S Scheiblhofer, J Laimer, Y Machado, R Weiss, J Thalhamer Expert review of vaccines 16 (5), 479-489, 2017 | 159 | 2017 |
Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen Y Machado, R Freier, S Scheiblhofer, T Thalhamer, M Mayr, P Briza, ... Journal of Allergy and Clinical Immunology 137 (5), 1525-1534, 2016 | 88 | 2016 |
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome I Pablos, Y Machado, HCR de Jesus, Y Mohamud, R Kappelhoff, ... Cell reports 37 (4), 2021 | 78 | 2021 |
Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction V Russo, T Klein, DJ Lim, N Solis, Y Machado, S Hiroyasu, L Nabai, ... Scientific reports 8 (1), 9690, 2018 | 64 | 2018 |
Isoelectric point optimization using peptide descriptors and support vector machines Y Perez-Riverol, E Audain, A Millan, Y Ramos, A Sanchez, JA Vizcaíno, ... Journal of proteomics 75 (7), 2269-2274, 2012 | 47 | 2012 |
Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy Y Machado, S Duinkerken, V Hoepflinger, M Mayr, E Korotchenko, ... Journal of Controlled Release 266, 87-99, 2017 | 34 | 2017 |
Role of B-1 cells in the immune response against an antigen encapsulated into phosphatidylcholine-containing liposomes Y Cruz-Leal, Y Machado, A López-Requena, L Canet, R Laborde, ... International immunology 26 (8), 427-437, 2014 | 26 | 2014 |
New approaches to transcutaneous immunotherapy: targeting dendritic cells with novel allergen conjugates R Weiss, S Scheiblhofer, Y Machado, J Thalhamer Current opinion in allergy and clinical immunology 13 (6), 669-676, 2013 | 25 | 2013 |
Proteomics based on peptide fractionation by SDS-free PAGE Y Ramos, E Gutierrez, Y Machado, A Sánchez, L Castellanos-Serra, ... Journal of proteome research 7 (6), 2427-2434, 2008 | 25 | 2008 |
TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice GR Araujo, L Aglas, ER Vaz, Y Machado, S Huber, M Himly, A Duschl, ... Allergy 75 (4), 882-891, 2020 | 23 | 2020 |
Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase PG Jobin, N Solis, Y Machado, PA Bell, NH Kwon, S Kim, CM Overall, ... Journal of Biological Chemistry 294 (35), 12866-12879, 2019 | 22 | 2019 |
Effect of structural stability on endolysosomal degradation and T‐cell reactivity of major shrimp allergen tropomyosin SD Kamath, S Scheiblhofer, CM Johnson, Y Machado, T McLean, AC Taki, ... Allergy 75 (11), 2909-2919, 2020 | 21 | 2020 |
Distinct epitope structures of defensin‐like proteins linked to proline‐rich regions give rise to differences in their allergenic activity I Pablos, S Eichhorn, Y Machado, P Briza, A Neunkirchner, ... Allergy 73 (2), 431-441, 2018 | 21 | 2018 |
Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage PG Jobin, N Solis, Y Machado, PA Bell, SK Rai, NH Kwon, S Kim, ... Journal of Biological Chemistry 295 (8), 2186-2202, 2020 | 18 | 2020 |
Potential of nanoparticles for allergen-specific immunotherapy–use of silica nanoparticles as vaccination platform S Scheiblhofer, Y Machado, A Feinle, J Thalhamer, N Hüsing, R Weiss Expert opinion on drug delivery 13 (12), 1777-1788, 2016 | 17 | 2016 |
Physicochemical and biological characterization of 1E10 anti-idiotype vaccine YJ Machado, Y Rabasa, R Montesinos, J Cremata, V Besada, D Fuentes, ... BMC biotechnology 11, 1-13, 2011 | 14 | 2011 |
Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris R García-Fernández, P Ziegelmüller, L González, M Mansur, Y Machado, ... Protein Expression and Purification 123, 42-50, 2016 | 12 | 2016 |
Enzymatically releasable polyethylene glycol–host defense peptide conjugates with improved activity and biocompatibility M Drayton, MA Alford, D Pletzer, EF Haney, Y Machado, HD Luo, ... Journal of Controlled Release 339, 220-231, 2021 | 11 | 2021 |
Bio-analytical method based on MALDI-MS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma A Cabrales-Rico, BG de la Torre, HE Garay, YJ Machado, JA Gómez, ... Journal of Pharmaceutical and Biomedical Analysis 105, 107-114, 2015 | 9 | 2015 |
Phosphocholine-specific antibodies improve T-dependent antibody responses against OVA encapsulated into phosphatidylcholine-containing liposomes Y Cruz-Leal, A López-Requena, I Lopetegui-González, Y Machado, ... Frontiers in immunology 7, 374, 2016 | 8 | 2016 |