Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain S Rose, S Melnyk, O Pavliv, S Bai, TG Nick, RE Frye, SJ James Translational psychiatry 2 (7), e134-e134, 2012 | 488 | 2012 |
Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism SJ James, S Rose, S Melnyk, S Jernigan, S Blossom, O Pavliv, DW Gaylor The FASEB Journal 23 (8), 2374, 2009 | 281 | 2009 |
Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism S Melnyk, GJ Fuchs, E Schulz, M Lopez, SG Kahler, JJ Fussell, J Bellando, ... Journal of autism and developmental disorders 42, 367-377, 2012 | 272 | 2012 |
Clinical and molecular characteristics of mitochondrial dysfunction in autism spectrum disorder S Rose, DM Niyazov, DA Rossignol, M Goldenthal, SG Kahler, RE Frye Molecular diagnosis & therapy 22, 571-593, 2018 | 216 | 2018 |
Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort S Rose, RE Frye, J Slattery, R Wynne, M Tippett, O Pavliv, S Melnyk, ... PloS one 9 (1), e85436, 2014 | 185 | 2014 |
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial RE Frye, J Slattery, L Delhey, B Furgerson, T Strickland, M Tippett, ... Molecular psychiatry 23 (2), 247-256, 2018 | 178 | 2018 |
Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism S Rose, SC Bennuri, JE Davis, R Wynne, JC Slattery, M Tippett, L Delhey, ... Translational psychiatry 8 (1), 42, 2018 | 175 | 2018 |
Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome RE Frye, S Rose, J Slattery, DF MacFabe Microbial ecology in health and disease 26 (1), 27458, 2015 | 171 | 2015 |
Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism S Jill James, S Melnyk, S Jernigan, A Hubanks, S Rose, DW Gaylor Journal of autism and developmental disorders 38, 1966-1975, 2008 | 157 | 2008 |
Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism S Rose, S Melnyk, TA Trusty, O Pavliv, L Seidel, J Li, T Nick, SJ James Autism research and treatment 2012 (1), 986519, 2012 | 112 | 2012 |
Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines RE Frye, S Rose, J Chacko, R Wynne, SC Bennuri, JC Slattery, M Tippett, ... Translational psychiatry 6 (10), e927-e927, 2016 | 107 | 2016 |
Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines S Rose, RE Frye, J Slattery, R Wynne, M Tippett, S Melnyk, SJ James Translational psychiatry 4 (4), e377-e377, 2014 | 91 | 2014 |
Mitochondrial dysfunction in the gastrointestinal mucosa of children with autism: a blinded case-control study S Rose, SC Bennuri, KF Murray, T Buie, H Winter, RE Frye PLoS One 12 (10), e0186377, 2017 | 77 | 2017 |
Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study S Rose, SC Bennuri, R Wynne, S Melnyk, SJ James, RE Frye The FASEB Journal 31 (3), 904, 2017 | 71 | 2017 |
Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism K Connery, M Tippett, LM Delhey, S Rose, JC Slattery, SG Kahler, J Hahn, ... Translational psychiatry 8 (1), 148, 2018 | 63 | 2018 |
Blocking and binding folate receptor alpha autoantibodies identify novel autism spectrum disorder subgroups RE Frye, L Delhey, J Slattery, M Tippett, R Wynne, S Rose, SG Kahler, ... Frontiers in neuroscience 10, 80, 2016 | 62 | 2016 |
Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology RE Frye, J Cakir, S Rose, L Delhey, SC Bennuri, M Tippett, S Melnyk, ... Molecular psychiatry 26 (5), 1561-1577, 2021 | 52 | 2021 |
Modulation of immunological pathways in autistic and neurotypical lymphoblastoid cell lines by the enteric microbiome metabolite propionic acid RE Frye, B Nankova, S Bhattacharyya, S Rose, SC Bennuri, DF MacFabe Frontiers in immunology 8, 1670, 2017 | 46 | 2017 |
Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder RE Frye, R Wynne, S Rose, J Slattery, L Delhey, M Tippett, SG Kahler, ... Journal of Neuroendocrinology 29 (3), 2017 | 44 | 2017 |
The effect of mitochondrial supplements on mitochondrial activity in children with autism spectrum disorder LM Delhey, E Nur Kilinc, L Yin, JC Slattery, ML Tippett, S Rose, ... Journal of clinical medicine 6 (2), 18, 2017 | 43 | 2017 |