Self-organized resonance during search of a diverse chemical space T Kachman, JA Owen, JL England Physical Review Letters 119 (3), 038001, 2017 | 62 | 2017 |
Universal thermodynamic bounds on nonequilibrium response with biochemical applications JA Owen, TR Gingrich, JM Horowitz Physical Review X 10 (1), 011066, 2020 | 44 | 2020 |
A space–time tradeoff for implementing a function with master equation dynamics DH Wolpert, A Kolchinsky, JA Owen Nature Communications 10 (1), 1727, 2019 | 37* | 2019 |
A fundamental trade-off in covalent switching and its circumvention by enzyme bifunctionality in glucose homeostasis T Dasgupta, DH Croll, JA Owen, MG Vander Heiden, JW Locasale, ... Journal of Biological Chemistry 289 (19), 13010-13025, 2014 | 35 | 2014 |
Number of hidden states needed to physically implement a given conditional distribution JA Owen, A Kolchinsky, DH Wolpert New Journal of Physics 21 (1), 013022, 2019 | 27 | 2019 |
Design principles of 3D epigenetic memory systems JA Owen, D Osmanović, L Mirny Science 382 (6672), eadg3053, 2023 | 24 | 2023 |
Size limits the sensitivity of kinetic schemes JA Owen, JM Horowitz Nature Communications 14 (1), 1280, 2023 | 14 | 2023 |
Controlling seizure-like events by perturbing ion concentration dynamics with periodic stimulation JA Owen, E Barreto, JR Cressman PLOS ONE 8 (9), e73820, 2013 | 13 | 2013 |
Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling IM Overton, AH Sims, JA Owen, BSE Heale, MJ Ford, ALR Lubbock, ... Cancers 12 (10), 2823, 2020 | 8 | 2020 |
Thermodynamic bounds on ultrasensitivity in covalent switching JA Owen, P Talla, JW Biddle, J Gunawardena Biophysical Journal 122 (10), 1833-1845, 2023 | 4 | 2023 |
Protein Editing using a Concerted Transposition Reaction Y Hua, NES Tay, X Ye, JA Owen, H Liu, R Thompson, TW Muir bioRxiv, 2024.06. 03.597171, 2024 | | 2024 |
Exponential sensitivity by a nonequilibrium cooperativity mechanism J Owen, J Horowitz Bulletin of the American Physical Society, 2023 | | 2023 |
Limited spreading enzyme stabilizes epigenetic memory J Owen, D Osmanovic, L Mirny Bulletin of the American Physical Society, 2022 | | 2022 |
Sensitivity and Memory in Physics and Biology JA Owen Massachusetts Institute of Technology, 2022 | | 2022 |
Thermodynamic Bounds on the Range and Sensitivity of Covalent Switching JA Owen, P Talla, JW Biddle, J Gunawardena Biophysical Journal 118 (3), 133a, 2020 | | 2020 |
The minimal “hidden” computer needed to implement a computation D Wolpert, J Owen, A Kolchinsky Bulletin of the American Physical Society, 2018 | | 2018 |