Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ... Cell 181 (5), 1004-1015. e15, 2020 | 658 | 2020 |
M2e-based universal influenza A vaccine W Fiers, M De Filette, K El Bakkouri, B Schepens, K Roose, M Schotsaert, ... Vaccine 27 (45), 6280-6283, 2009 | 300 | 2009 |
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ... Nature communications 11 (1), 5838, 2020 | 280 | 2020 |
Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly J Verhelst, E Parthoens, B Schepens, W Fiers, X Saelens Journal of virology 86 (24), 13445-13455, 2012 | 268 | 2012 |
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules A Hultberg, NJ Temperton, V Rosseels, M Koenders, M Gonzalez-Pajuelo, ... PloS one 6 (4), e17665, 2011 | 214 | 2011 |
Nanobodies®: new ammunition to battle viruses P Vanlandschoot, C Stortelers, E Beirnaert, LI Ibañez, B Schepens, ... Antiviral research 92 (3), 389-407, 2011 | 177 | 2011 |
Nanobodies with in vitro neutralizing activity protect mice against H5N1 influenza virus infection LI Ibanez, M De Filette, A Hultberg, T Verrips, N Temperton, RA Weiss, ... Journal of Infectious Diseases 203 (8), 1063-1072, 2011 | 128 | 2011 |
M2-based influenza vaccines: recent advances and clinical potential A Kolpe, B Schepens, W Fiers, X Saelens Expert review of vaccines 16 (2), 123-136, 2017 | 127 | 2017 |
A role for hnRNP C1/C2 and Unr in internal initiation of translation during mitosis B Schepens, SA Tinton, Y Bruynooghe, E Parthoens, M Haegman, ... The EMBO journal 26 (1), 158-169, 2007 | 126 | 2007 |
The polypyrimidine tract-binding protein stimulates HIF-1α IRES-mediated translation during hypoxia B Schepens, SA Tinton, Y Bruynooghe, R Beyaert, S Cornelis Nucleic acids research 33 (21), 6884-6894, 2005 | 116 | 2005 |
Developing 3D SEM in a broad biological context A Kremer, S Lippens, S Bartunkova, B Asselbergh, C Blanpain, ... Journal of microscopy 259 (2), 80-96, 2015 | 115 | 2015 |
Regulation of the cell-cycle-dependent internal ribosome entry site of the PITSLRE protein kinase: Roles of Unr (upstream of N-ras) protein and phosphorylated translation … SA Tinton, B Schepens, Y Bruynooghe, R Beyaert, S Cornelis Biochemical Journal 385 (1), 155-163, 2005 | 107 | 2005 |
UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein S Cornelis, SA Tinton, B Schepens, Y Bruynooghe, R Beyaert Nucleic acids research 33 (10), 3095-3108, 2005 | 96 | 2005 |
Single-domain antibodies and their formatting to combat viral infections D De Vlieger, M Ballegeer, I Rossey, B Schepens, X Saelens Antibodies 8 (1), 1, 2018 | 87 | 2018 |
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state I Rossey, MSA Gilman, SC Kabeche, K Sedeyn, D Wrapp, M Kanekiyo, ... Nature communications 8 (1), 14158, 2017 | 85 | 2017 |
Hepatitis B core–based virus–like particles to present heterologous epitopes K Roose, SD Baets, B Schepens, X Saelens Expert review of vaccines 12 (2), 183-198, 2013 | 82 | 2013 |
Hierarchical and redundant roles of activating FcγRs in protection against influenza disease by M2e-specific IgG1 and IgG2a antibodies S Van den Hoecke, K Ehrhardt, A Kolpe, K El Bakkouri, L Deng, ... Journal of virology 91 (7), 10.1128/jvi. 02500-16, 2017 | 79 | 2017 |
Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge FM Cardoso, LI Ibañez, S Van den Hoecke, S De Baets, A Smet, K Roose, ... Journal of virology 88 (15), 8278-8296, 2014 | 78 | 2014 |
Nanobodies® specific for respiratory syncytial virus fusion protein protect against infection by inhibition of fusion B Schepens, LIÍ Ibanez, S De Baets, A Hultberg, P Bogaert, P De Bleser, ... Journal of Infectious Diseases 204 (11), 1692-1701, 2011 | 77 | 2011 |
Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody KJ Cho, B Schepens, JH Seok, S Kim, K Roose, JH Lee, R Gallardo, ... Journal of virology 89 (7), 3700-3711, 2015 | 75 | 2015 |