Methods for reliability and uncertainty assessment and for applicability evaluations of classification-and regression-based QSARs. L Eriksson, J Jaworska, AP Worth, MTD Cronin, RM McDowell, ... Environmental health perspectives 111 (10), 1361-1375, 2003 | 1486 | 2003 |
Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52 TI Netzeva, AP Worth, T Aldenberg, R Benigni, MTD Cronin, P Gramatica, ... Alternatives to Laboratory Animals 33 (2), 155-173, 2005 | 886 | 2005 |
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85, 367-485, 2011 | 637 | 2011 |
An evaluation of the implementation of the Cramer classification scheme in the Toxtree software G Patlewicz, N Jeliazkova, RJ Safford, AP Worth, B Aleksiev SAR and QSAR in Environmental Research 19 (5-6), 495-524, 2008 | 435 | 2008 |
A modular approach to the ECVAM principles on test validity T Hartung, S Bremer, S Casati, S Coecke, R Corvi, S Fortaner, L Gribaldo, ... Alternatives to Laboratory Animals 32 (5), 467-472, 2004 | 375 | 2004 |
Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA) KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ... Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014 | 356 | 2014 |
A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles E Burello, AP Worth Nanotoxicology 5 (2), 228-235, 2011 | 347 | 2011 |
Use of QSARs in international decision-making frameworks to predict health effects of chemical substances. MTD Cronin, JS Jaworska, JD Walker, MHI Comber, CD Watts, AP Worth Environmental health perspectives 111 (10), 1391-1401, 2003 | 335 | 2003 |
CERAPP: collaborative estrogen receptor activity prediction project K Mansouri, A Abdelaziz, A Rybacka, A Roncaglioni, A Tropsha, A Varnek, ... Environmental health perspectives 124 (7), 1023-1033, 2016 | 318 | 2016 |
The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity … H Spielmann, S Hoffmann, M Liebsch, P Botham, JH Fentem, C Eskes, ... Alternatives to Laboratory Animals 35 (6), 559-601, 2007 | 248 | 2007 |
Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. MTD Cronin, JD Walker, JS Jaworska, MHI Comber, CD Watts, AP Worth Environmental Health Perspectives 111 (10), 1376-1390, 2003 | 245 | 2003 |
Regulatory assessment of chemical mixtures: requirements, current approaches and future perspectives A Kienzler, SK Bopp, S van der Linden, E Berggren, A Worth Regulatory Toxicology and Pharmacology 80, 321-334, 2016 | 242 | 2016 |
Metabolism: A Bottleneck in In Vitro Toxicological Test Development: The Report and Recommendations of ECVAM Workshop 54 S Coecke, H Ahr, BJ Blaauboer, S Bremer, S Casati, J Castell, R Combes, ... Alternatives to Laboratory Animals 34 (1), 49-84, 2006 | 219 | 2006 |
Applying quantitative structure–activity relationship approaches to nanotoxicology: current status and future potential DA Winkler, E Mombelli, A Pietroiusti, L Tran, A Worth, B Fadeel, ... Toxicology 313 (1), 15-23, 2013 | 199 | 2013 |
New publicly available chemical query language, CSRML, to support chemotype representations for application to data mining and modeling C Yang, A Tarkhov, J Marusczyk, B Bienfait, J Gasteiger, T Kleinoeder, ... Journal of chemical information and modeling 55 (3), 510-528, 2015 | 183 | 2015 |
Regulatory assessment and risk management of chemical mixtures: challenges and ways forward SK Bopp, A Kienzler, AN Richarz, SC van der Linden, A Paini, N Parissis, ... Critical Reviews in Toxicology 49 (2), 174-189, 2019 | 182 | 2019 |
QSAR modeling of nanomaterials E Burello, AP Worth Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 3 (3 …, 2011 | 171 | 2011 |
The role of the European Chemicals Bureau in promoting the regulatory use of (Q) SAR methods AP Worth, A Bassan, J De Bruijn, A Gallegos Saliner, T Netzeva, M Pavan, ... SAR and QSAR in Environmental Research 18 (1-2), 111-125, 2007 | 170 | 2007 |
The registry of cytotoxicity: toxicity testing in cell cultures to predict acute toxicity (LD50) and to reduce testing in animals W Halle, M Halder, A Worth, E Genschow Alternatives to Laboratory Animals 31 (2), 89-89, 2003 | 161 | 2003 |
The development and validation of expert systems for predicting toxicity: The report and recommendations of an ECVAM/ECB workshop (ECVAM Workshop 24) JC Dearden, MD Barratt, R Benigni, DW Bristol, RD Combes, MTD Cronin, ... Alternatives to laboratory animals 25 (3), 223-251, 1997 | 160 | 1997 |