High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22 M Gulhane, L Murray, R Lourie, H Tong, YH Sheng, R Wang, A Kang, ... Scientific reports 6 (1), 28990, 2016 | 328 | 2016 |
Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate N Pujara, S Jambhrunkar, KY Wong, M McGuckin, A Popat Journal of Colloid and Interface Science 488, 303-308, 2017 | 159 | 2017 |
In Vitro Dissolution, Cellular Membrane Permeability, and Anti-Inflammatory Response of Resveratrol-Encapsulated Mesoporous Silica Nanoparticles E Juère, J Florek, M Bouchoucha, S Jambhrunkar, KY Wong, A Popat, ... Molecular Pharmaceutics 14 (12), 4431-4441, 2017 | 98 | 2017 |
MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target YH Sheng, Y He, SZ Hasnain, R Wang, H Tong, DT Clarke, R Lourie, ... Oncogene 36 (5), 700-713, 2017 | 84 | 2017 |
Enhanced solubility, permeability and anticancer activity of vorinostat using tailored mesoporous silica nanoparticles AK Meka, LJ Jenkins, M Dàvalos-Salas, N Pujara, KY Wong, T Kumeria, ... Pharmaceutics 10 (4), 283, 2018 | 53 | 2018 |
MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance Y Sheng, CP Ng, R Lourie, ET Shah, Y He, KY Wong, I Seim, I Oancea, ... International journal of cancer 140 (10), 2351-2363, 2017 | 43 | 2017 |
Oral delivery of β-lactoglobulin-nanosphere-encapsulated resveratrol alleviates inflammation in winnie mice with spontaneous ulcerative colitis N Pujara, KY Wong, Z Qu, R Wang, MD Moniruzzaman, P Rewatkar, ... Molecular Pharmaceutics 18 (2), 627-640, 2020 | 42 | 2020 |
pH–Responsive colloidal carriers assembled from β-lactoglobulin and Epsilon poly-L-lysine for oral drug delivery N Pujara, R Giri, KY Wong, Z Qu, P Rewatkar, M Moniruzzaman, J Begun, ... Journal of Colloid and Interface Science 589, 45-55, 2021 | 38 | 2021 |
One‐Pot Synthesis of pH‐Responsive Eudragit‐Mesoporous Silica Nanocomposites Enable Colonic Delivery of Glucocorticoids for the Treatment of Inflammatory Bowel Disease Z Qu, KY Wong, M Moniruzzaman, J Begun, HA Santos, SZ Hasnain, ... Advanced therapeutics 4 (2), 2000165, 2021 | 36 | 2021 |
MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity YH Sheng, KY Wong, I Seim, R Wang, Y He, A Wu, M Patrick, R Lourie, ... Oncogene 38 (48), 7294-7310, 2019 | 35 | 2019 |
CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin Y He, CM Davies, BS Harrington, L Hellmers, Y Sheng, A Broomfield, ... Oncogene 39 (1), 219-233, 2020 | 31 | 2020 |
Gut microbiota shape the inflammatory response in mice with an epithelial defect R Wang, M Moniruzzaman, KY Wong, P Wiid, A Harding, R Giri, W Tong, ... Gut Microbes 13 (1), 1887720, 2021 | 29 | 2021 |
CD83 Antibody Inhibits Human B Cell Responses to Antigen as well as Dendritic Cell–Mediated CD4 T Cell Responses KY Wong, R Baron, TA Seldon, ML Jones, AM Rice, DJ Munster The Journal of Immunology 200 (10), 3383-3396, 2018 | 12 | 2018 |
High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. Sci Rep 6: 28990 M Gulhane, L Murray, R Lourie, H Tong, YH Sheng, R Wang, A Kang, ... | 11 | 2016 |
MUC1-mediated macrophage activation promotes colitis-associated colorectal cancer via activating the interleukin-6/signal transducer and activator of transcription 3 axis YH Sheng, JM Davies, R Wang, KY Wong, R Giri, Y Yang, J Begun, ... Cellular and Molecular Gastroenterology and Hepatology 14 (4), 789-811, 2022 | 6 | 2022 |
Interleukin-22 suppresses major histocompatibility complex II in mucosal epithelial cells M Moniruzzaman, MA Rahman, R Wang, KY Wong, ACH Chen, A Mueller, ... Journal of Experimental Medicine 220 (11), e20230106, 2023 | 5 | 2023 |
MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier MA McGuckin, JM Davies, P Felgner, KY Wong, R Giri, Y He, ... Cellular and Molecular Gastroenterology and Hepatology 16 (6), 985-1009, 2023 | 4 | 2023 |
Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis H Sajiir, S Keshvari, KY Wong, DJ Borg, FJ Steyn, C Fercher, K Taylor, ... Nature Communications 15 (1), 4528, 2024 | 2 | 2024 |
Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis H Sajiir, KY Wong, A Müller, S Keshvari, L Burr, E Aiello, T Mezza, ... Nature Communications 15 (1), 4527, 2024 | 2 | 2024 |
IL-20 Activates ERK1/2 and Suppresses Splicing of X-Box Protein-1 in Intestinal Epithelial Cells but Does Not Improve Pathology in Acute or Chronic Models of Colitis M Moniruzzaman, KY Wong, R Wang, H Symon, A Mueller, MA Rahman, ... International Journal of Molecular Sciences 24 (1), 174, 2022 | 1 | 2022 |