Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models LM Ittner, YD Ke, F Delerue, M Bi, A Gladbach, J van Eersel, H Wölfing, ... Cell 142 (3), 387-397, 2010 | 2080 | 2010 |
Cloning and expression of a rat D2 dopamine receptor cDNA JR Bunzow, HHMV Tol, DK Grandy, P Albert, J Salon, MD Christie, ... Nature 336 (6201), 783-787, 1988 | 1543 | 1988 |
Cellular and synaptic adaptations mediating opioid dependence JT Williams, MDJ Christie, O Manzoni Physiological reviews 81 (1), 299-343, 2001 | 1148 | 2001 |
Regulation of µ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance JT Williams, SL Ingram, G Henderson, C Chavkin, M von Zastrow, ... Pharmacological reviews 65 (1), 223-254, 2013 | 877 | 2013 |
Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. RA North, JT Williams, A Surprenant, MJ Christie Proceedings of the National Academy of Sciences 84 (15), 5487-5491, 1987 | 844 | 1987 |
How opioids inhibit GABA-mediated neurotransmission CW Vaughan, SL Ingram, MA Connor, MJ Christie Nature 390 (6660), 611-614, 1997 | 607 | 1997 |
Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction MJ Christie British journal of pharmacology 154 (2), 384-396, 2009 | 569 | 2009 |
Conus venom peptide pharmacology RJ Lewis, S Dutertre, I Vetter, MDJ Christie Pharmacological reviews 64 (2), 259-298, 2012 | 495 | 2012 |
Excitatory amino acid projections to the nucleus accumbens septi in the rat: a retrograde transport study utilizingd [3H] aspartate and [3H] GABA MJ Christie, RJ Summers, JA Stephenson, CJ Cook, PM Beart Neuroscience 22 (2), 425-439, 1987 | 408 | 1987 |
Opioid receptor signalling mechanisms M Connor, MDJ Christie Clinical and experimental pharmacology and physiology 26 (7), 493-499, 1999 | 406 | 1999 |
Cellular mechanisms of opioid tolerance: studies in single brain neurons. MJ Christie, JT Williams, RA North Molecular pharmacology 32 (5), 633-638, 1987 | 365 | 1987 |
Heteropolymeric potassium channels expressed in Xenopus oocytes from cloned subunits MJ Christie, RA North, PB Osborne, J Douglass, JP Adelman Neuron 4 (3), 405-411, 1990 | 337 | 1990 |
Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human MM Morgan, MDJ Christie British journal of pharmacology 164 (4), 1322-1334, 2011 | 316 | 2011 |
Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro CW Vaughan, M Connor, EE Bagley, MDJ Christie Molecular Pharmacology 57 (2), 288-295, 2000 | 296 | 2000 |
Gingerols: a novel class of vanilloid receptor (VR1) agonists VN Dedov, VH Tran, CC Duke, M Connor, MDJ Christie, S Mandadi, ... British journal of pharmacology 137 (6), 793, 2002 | 286 | 2002 |
Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects A Kliewer, F Schmiedel, S Sianati, A Bailey, JT Bateman, ES Levitt, ... Nature communications 10 (1), 367, 2019 | 279 | 2019 |
Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area MJ Christie, S Bridge, LB James, PM Beart Brain research 333 (1), 169-172, 1985 | 276 | 1985 |
Increase by the ORL1 receptor (opioid receptor‐like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones CW Vaughan, MJ Christie British journal of pharmacology 117 (8), 1609-1611, 1996 | 263 | 1996 |
Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. CW Vaughan, MJ Christie The Journal of physiology 498 (2), 463-472, 1997 | 262 | 1997 |
Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists A Gillis, AB Gondin, A Kliewer, J Sanchez, HD Lim, C Alamein, ... Science signaling 13 (625), eaaz3140, 2020 | 258 | 2020 |