| Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma JR Park, DL DiGiusto, M Slovak, C Wright, A Naranjo, J Wagner, ... Molecular therapy 15 (4), 825-833, 2007 | 731 | 2007 |
| Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans MC Jensen, L Popplewell, LJ Cooper, D DiGiusto, M Kalos, JR Ostberg, ... Biology of blood and marrow transplantation 16 (9), 1245-1256, 2010 | 653 | 2010 |
| RNA-based gene therapy for HIV with lentiviral vector–modified CD34+ cells in patients undergoing transplantation for AIDS-related lymphoma DL DiGiusto, A Krishnan, L Li, H Li, S Li, A Rao, S Mi, P Yam, S Stinson, ... Science translational medicine 2 (36), 36ra43-36ra43, 2010 | 512 | 2010 |
| Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion B Kumar, M Garcia, L Weng, X Jung, JL Murakami, X Hu, T McDonald, ... Leukemia 32 (3), 575-587, 2018 | 406 | 2018 |
| Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases L Li, L Krymskaya, J Wang, J Henley, A Rao, LF Cao, CA Tran, ... Molecular Therapy 21 (6), 1259-1269, 2013 | 217 | 2013 |
| Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34 D DiGiusto, S Chen, J Combs, S Webb, R Namikawa, A Tsukamoto, ... | 157 | 1994 |
| Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells DL DiGiusto, PM Cannon, MC Holmes, L Li, A Rao, J Wang, G Lee, ... Molecular therapy Methods & clinical development 3, 2016 | 128 | 2016 |
| Retention of quiescent hematopoietic cells with high proliferative potential during ex vivo stem cell culture JC Young, A Varma, D DiGiusto, MP Backer | 119 | 1996 |
| STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma A Scuto, M Kujawski, C Kowolik, L Krymskaya, L Wang, LM Weiss, ... Cancer research 71 (9), 3182-3188, 2011 | 118 | 2011 |
| Hematopoietic potential of cryopreserved and ex vivo manipulated umbilical cord blood progenitor cells evaluated in vitro and in vivo DL DiGiusto, R Lee, J Moon, K Moss, T O'Toole, A Voytovich, D Webster, ... | 116 | 1996 |
| Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ... Science translational medicine 13 (598), eabf2444, 2021 | 106 | 2021 |
| Manufacturing of gene-modified cytotoxic T lymphocytes for autologous cellular therapy for lymphoma LJN Cooper, L Ausubel, M Gutierrez, S Stephan, R Shakeley, S Olivares, ... Cytotherapy 8 (2), 105-117, 2006 | 95 | 2006 |
| Development and application of CD19-specific T cells for adoptive immunotherapy of B cell malignancies LJN Cooper, Z Al-Kadhimi, D DiGiusto, M Kalos, D Colcher, ... Blood Cells, Molecules, and Diseases 33 (1), 83-89, 2004 | 67 | 2004 |
| Development of hematopoietic stem cell based gene therapy for HIV-1 infection: considerations for proof of concept studies and translation to standard medical practice DL DiGiusto, R Stan, A Krishnan, H Li, JJ Rossi, JA Zaia Viruses 5 (11), 2898-2919, 2013 | 61 | 2013 |
| Method for producing a highly enriched population of hematopoietic stem cells D DiGiusto, A Galy US Patent 5,681,559, 1997 | 56 | 1997 |
| Analysis of human hematopoietic stem cell populations. L Murray, D DiGiusto, B Chen, S Chen, J Combs, A Conti, A Galy, ... Blood Cells 20 (2-3), 364-9; discussion 369, 1994 | 54 | 1994 |
| Toxicity-free hematopoietic stem cell engraftment achieved with anti-CD117 monoclonal antibody conditioning R Agarwal, CC Dvorak, S Prohaska, J Long-Boyle, HS Kwon, KI Weinberg, ... Biology of Blood and Marrow Transplantation 25 (3), S92, 2019 | 46 | 2019 |
| Manufacturing of large numbers of patient-specific T cells for adoptive immunotherapy: an approach to improving product safety, composition, and production capacity CA Tran, L Burton, D Russom, JR Wagner, MC Jensen, SJ Forman, ... Journal of Immunotherapy 30 (6), 644-654, 2007 | 46 | 2007 |
| Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMTP140K drug resistance gene J Chung, LJ Scherer, A Gu, AM Gardner, M Torres-Coronado, EW Epps, ... Molecular Therapy 22 (5), 952-963, 2014 | 35 | 2014 |
| Human marrow-derived mesodermal progenitor cells generate insulin-secreting islet-like clusters in vivo C Ai, I Todorov, ML Slovak, D Digiusto, SJ Forman, CC Shih Stem cells and development 16 (5), 757-770, 2007 | 34 | 2007 |
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