| Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling MV Westphal, MA Schafroth, RC Sarott, MA Imhof, CP Bold, P Leippe, ... Journal of the American Chemical Society 139 (50), 18206-18212, 2017 | 95 | 2017 |
| Optical Control of Cannabinoid Receptor 2-Mediated Ca2+ Release Enabled by Synthesis of Photoswitchable Probes RC Sarott, AEG Viray, P Pfaff, A Sadybekov, G Rajic, V Katritch, ... Journal of the American Chemical Society 143 (2), 736-743, 2021 | 42 | 2021 |
| Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks M Müller, F Gräbnitz, N Barandun, Y Shen, F Wendt, SN Steiner, ... Nature Communications 12 (1), 7036, 2021 | 41 | 2021 |
| Development of high-specificity fluorescent probes to enable cannabinoid type 2 receptor studies in living cells RC Sarott, MV Westphal, P Pfaff, C Korn, DA Sykes, T Gazzi, B Brennecke, ... Journal of the American Chemical Society 142 (40), 16953-16964, 2020 | 38 | 2020 |
| Synthesis, characterization and initial evaluation of 5-nitro-1-(trifluoromethyl)-3H-1λ3, 2-benziodaoxol-3-one N Santschi, RC Sarott, E Otth, R Kissner, A Togni Beilstein journal of organic chemistry 10 (1), 1-6, 2014 | 31 | 2014 |
| Highly Selective, Amine‐Derived Cannabinoid Receptor 2 Probes MV Westphal, RC Sarott, EA Zirwes, A Osterwald, W Guba, C Ullmer, ... Chemistry–A European Journal 26 (6), 1380-1387, 2020 | 24 | 2020 |
| Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe T Gazzi, B Brennecke, K Atz, C Korn, D Sykes, G Forn-Cuni, P Pfaff, ... Chemical Science 13 (19), 5539-5545, 2022 | 19 | 2022 |
| Cannabinoid CB2 Receptors Modulate Microglia Function and Amyloid Dynamics in a Mouse Model of Alzheimer’s Disease S Ruiz de Martín Esteban, I Benito-Cuesta, I Terradillos, ... Frontiers in pharmacology 13, 841766, 2022 | 18 | 2022 |
| Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry RC Sarott, I You, YD Li, ST Toenjes, KA Donovan, P Seo, M Ordonez, ... Journal of the American Chemical Society 145 (40), 21937-21944, 2023 | 10 | 2023 |
| Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells M Kosar, DA Sykes, AEG Viray, RM Vitale, RC Sarott, RL Ganzoni, ... Journal of the American Chemical Society 145 (28), 15094-15108, 2023 | 7 | 2023 |
| Drug derived fluorescent probes for the specific visualization of cannabinoid type 2 receptor-a toolbox approach T Gazzi, B Brennecke, K Atz, C Korn, D Sykes, RC Sarott, MV Westphal, ... | 3 | 2019 |
| Flipping the GPCR switch: Structure-based development of selective cannabinoid receptor 2 inverse agonists M Kosar, RC Sarott, DA Sykes, AEG Viray, RM Vitale, N Tomašević, X Li, ... ACS Central Science 10 (5), 956-968, 2024 | 2 | 2024 |
| Highly Specific, Fluorescent Cannabinoid Type 2 Receptor Probes Enable Applications in Microscopy, Flow Cytometry and FRET-based Binding Assays R Sarott, M Westphal, P Pfaff, C Korn, D Sykes, T Gazzi, B Brennecke, ... | 2 | 2019 |
| Borrowing Transcriptional Kinases to Activate Apoptosis R Sarott, S Gourisankar, B Karim, S Nettles, H Yang, BG Dwyer, ... bioRxiv, 2023.10. 23.563687, 2023 | 1 | 2023 |
| Cobalt-Catalyzed Aerobic Aminocyclization of Unsaturated Amides for the Synthesis of Functionalized γ-and δ-Lactams M Freis, M Balkenhohl, DM Fischer, T Georgiev, RC Sarott, EM Carreira Organic Letters 25 (34), 6380-6384, 2023 | 1 | 2023 |
| Abstract PO-012: Gain-of-function small molecules to reprogram oncogenic transcription in lymphoma S Gourisankar, R Sarott, B Karim, S Nettles, H Yang, B Dwyer, ... Blood Cancer Discovery 5 (3_Supplement), PO-012-PO-012, 2024 | | 2024 |
| Conversion of THC, CBD and their derivatives to Cannabinol EM Carreira, R Sarott, P Pfaff, K Hurni, R Remo, S Eichenberger, J Stäubli US Patent 11,981,651, 2024 | | 2024 |
| Rewiring EWS/FLI1 with transcriptional chemical inducers of proximity (TCIPs) MJ Bond, RP Golden, RC Sarott, G DiGiovanni, BA Karim, B Howard, ... Cancer Research 84 (6_Supplement), 5777-5777, 2024 | | 2024 |
| Discovery of CRBN-dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library H Razumkov, Z Jiang, K Baek, I You, Q Geng, K Donovan, MT Tang, ... bioRxiv, 2024.05. 04.592550, 2024 | | 2024 |
| Out of the Dark, Into the Light: Fluorescent and Photoswitchable Probes for Cannabinoid Receptors RC Sarott ETH Zurich, 2021 | | 2021 |
