Antivirals against coronaviruses: candidate drugs for SARS-CoV-2 treatment? IA Santos, VR Grosche, FRG Bergamini, R Sabino-Silva, ACG Jardim Frontiers in microbiology 11, 1818, 2020 | 123 | 2020 |
What is holding back the development of antiviral metallodrugs? A literature overview and implications for SARS-CoV-2 therapeutics and future viral outbreaks REF de Paiva, AM Neto, IA Santos, ACG Jardim, PP Corbi, ... Dalton Transactions 49 (45), 16004-16033, 2020 | 87 | 2020 |
Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus IA Santos, JF Shimizu, DM de Oliveira, DOS Martins, L Cardoso-Sousa, ... Scientific Reports 11 (1), 8717, 2021 | 39 | 2021 |
Insights into the antiviral activity of phospholipases A2 (PLA2s) from snake venoms SC Teixeira, BC Borges, VQ Oliveira, LS Carregosa, LA Bastos, IA Santos, ... International journal of biological macromolecules 164, 616-625, 2020 | 30 | 2020 |
Antivirals against Chikungunya virus: is the solution in nature? D Oliveira Silva Martins, I de Andrade Santos, D Moraes de Oliveira, ... Viruses 12 (3), 272, 2020 | 25 | 2020 |
Organometallic complex strongly impairs chikungunya virus entry to the host cells DM Oliveira, IA Santos, DOS Martins, YG Gonçalves, L Cardoso-Sousa, ... Frontiers in Microbiology 11, 608924, 2020 | 24 | 2020 |
Discovery of an imidazonaphthyridine and a riminophenazine as potent anti-Zika virus agents through a replicon-based high-throughput screening RS Fernandes, AS de Godoy, IA Santos, GD Noske, KIZ de Oliveira, ... Virus Research 299, 198388, 2021 | 23 | 2021 |
Pathophysiology of SARS-CoV-2 in lung of diabetic patients TL Oliveira, IS Melo, L Cardoso-Sousa, IA Santos, MB El Zoghbi, ... Frontiers in Physiology 11, 587013, 2020 | 22 | 2020 |
Repurposing potential of rimantadine hydrochloride and development of a promising platinum (II)-rimantadine metallodrug for the treatment of Chikungunya virus infection IA Santos, AK dos Santos Pereira, M Guevara-Vega, REF de Paiva, ... Acta Tropica 227, 106300, 2022 | 19 | 2022 |
Memantine hydrochloride: a drug to be repurposed against Chikungunya virus? AKS Pereira, IA Santos, WW da Silva, FAR Nogueira, FRG Bergamini, ... Pharmacological Reports 73, 954-961, 2021 | 18 | 2021 |
In vitro and in vivo models for monkeypox RB Rosa, EF de Castro, MV da Silva, DCP Ferreira, ACG Jardim, ... Iscience 26 (1), 2023 | 16 | 2023 |
Synthesis, spectroscopic characterization and in vitro antibacterial and antiviral activities of novel silver (I) complexes with mafenide and ethyl-mafenide PG Esquezaro, CM Manzano, DH Nakahata, IA Santos, UEA Ruiz, ... Journal of Molecular Structure 1246, 131261, 2021 | 15 | 2021 |
Roles of Bothrops jararacussu toxins I and II: Antiviral findings against Zika virus NM Cassani, IA Santos, VR Grosche, GM Ferreira, M Guevara-Vega, ... International Journal of Biological Macromolecules 227, 630-640, 2023 | 11 | 2023 |
Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate MCLC Freire, LGM Basso, LFS Mendes, NCMR Mesquita, M Mottin, ... Scientific reports 12 (1), 10601, 2022 | 10 | 2022 |
In silico evaluation of lapachol derivatives binding to the Nsp9 of SARS-CoV-2 NN Junior, IA Santos, BA Meireles, MSAP Nicolau, IR Lapa, RS Aguiar, ... Journal of Biomolecular Structure and Dynamics 40 (13), 5917-5931, 2022 | 9 | 2022 |
Ensino inclusivo de pensamento computacional: um relato de experiência N Silva, I Santos, L Orleans Anais do XXVII Workshop sobre Educação em Computação, 81-90, 2019 | 9 | 2019 |
Insights into the role of the cobalt (III)-thiosemicarbazone complex as a potential inhibitor of the Chikungunya virus nsP4 DOS Martins, RAC Souza, MCLC Freire, NC de Moraes Roso Mesquita, ... JBIC Journal of Biological Inorganic Chemistry 28 (1), 101-115, 2023 | 8 | 2023 |
Natural compounds as non-nucleoside inhibitors of Zika virus polymerase through integration of in silico and in vitro approaches PRPS Ramos, M Mottin, CS Lima, LR Assis, KZ de Oliveira, ... Pharmaceuticals 15 (12), 1493, 2022 | 8 | 2022 |
Triphenylphosphine gold (I) derivatives promote antiviral effects against the Chikungunya virus RL Aires, IA Santos, JV Fontes, FRG Bergamini, ACG Jardim, ... Metallomics 14 (8), mfac056, 2022 | 8 | 2022 |
In vitro antiviral activity of piperidine alkaloids from Senna spectabilis flowers on Chikungunya virus infection TR Freitas, RM Novais, IA Santos, DOS Martins, A Danuello, ... Pharmacological Reports 74 (4), 752-758, 2022 | 7 | 2022 |