Genome-scale functional characterization of Drosophila developmental enhancers in vivo EZ Kvon, T Kazmar, G Stampfel, JO Yáñez-Cuna, M Pagani, ... Nature 512 (7512), 91-95, 2014 | 494 | 2014 |
Progressive loss of function in a limb enhancer during snake evolution EZ Kvon, OK Kamneva, US Melo, I Barozzi, M Osterwalder, BJ Mannion, ... Cell 167 (3), 633-642. e11, 2016 | 342 | 2016 |
Enhancer redundancy in development and disease EZ Kvon, R Waymack, M Gad, Z Wunderlich Nature Reviews Genetics 22 (5), 324-336, 2021 | 185 | 2021 |
HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature EZ Kvon, G Stampfel, JO Yáñez-Cuna, BJ Dickson, A Stark Genes & development 26 (9), 908-913, 2012 | 166 | 2012 |
Deciphering the transcriptional cis-regulatory code JO Yáñez-Cuna, EZ Kvon, A Stark Trends in Genetics 29 (1), 11-22, 2013 | 142 | 2013 |
Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding JO Yáñez-Cuna, HQ Dinh, EZ Kvon, D Shlyueva, A Stark Genome research 22 (10), 2018-2030, 2012 | 131 | 2012 |
Comprehensive in vivo interrogation reveals phenotypic impact of human enhancer variants EZ Kvon, Y Zhu, G Kelman, CS Novak, I Plajzer-Frick, M Kato, TH Garvin, ... Cell 180 (6), 1262-1271. e15, 2020 | 129 | 2020 |
Using transgenic reporter assays to functionally characterize enhancers in animals EZ Kvon Genomics 106 (3), 185-192, 2015 | 92 | 2015 |
An evolutionary conserved epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS R Rickels, D Hu, CK Collings, AR Woodfin, A Piunti, M Mohan, HM Herz, ... Molecular cell 63 (2), 318-328, 2016 | 75 | 2016 |
Ultraconserved enhancer function does not require perfect sequence conservation V Snetkova, AR Ypsilanti, JA Akiyama, BJ Mannion, I Plajzer-Frick, ... Nature genetics 53 (4), 521-528, 2021 | 58 | 2021 |
Presynaptic homeostasis opposes disease progression in mouse models of ALS-like degeneration: evidence for homeostatic neuroprotection BO Orr, AG Hauswirth, B Celona, RD Fetter, G Zunino, EZ Kvon, Y Zhu, ... Neuron 107 (1), 95-111. e6, 2020 | 45 | 2020 |
A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation C Yanchus, KL Drucker, TM Kollmeyer, R Tsai, W Winick-Ng, M Liang, ... Science 378 (6615), 68-78, 2022 | 37 | 2022 |
Gene density profile reveals the marking of late replicated domains in the Drosophila melanogaster genome SN Belyakin, VN Babenko, DA Maksimov, VV Shloma, EZ Kvon, ... Chromosoma 119, 589-600, 2010 | 37 | 2010 |
Characterization of mammalian in vivo enhancers using mouse transgenesis and CRISPR genome editing M Osterwalder, S Tran, RD Hunter, EM Meky, K von Maydell, ... Craniofacial Development: Methods and Protocols, 147-186, 2021 | 22 | 2021 |
Increased enhancer–promoter interactions during developmental enhancer activation in mammals Z Chen, V Snetkova, G Bower, S Jacinto, B Clock, A Dizehchi, I Barozzi, ... Nature Genetics 56 (4), 675-685, 2024 | 19* | 2024 |
Stable enhancers are active in development, and fragile enhancers are associated with evolutionary adaptation S Li, EZ Kvon, A Visel, LA Pennacchio, I Ovcharenko Genome biology 20, 1-17, 2019 | 10 | 2019 |
Drosophila embryo stage annotation using label propagation T Kazmar, EZ Kvon, A Stark, CH Lampert Proceedings of the IEEE International Conference on Computer Vision, 1089-1096, 2013 | 7 | 2013 |
Chromatin decompaction in the interbands of Drosophila polytene chromosomes does not correlate with high transcription level EZ Kvon, SA Demakov, IF Zhimulev Russian Journal of Genetics 47, 674-681, 2011 | 4 | 2011 |
Emx2 underlies the development and evolution of marsupial gliding membranes JA Moreno, O Dudchenko, CY Feigin, SA Mereby, Z Chen, R Ramos, ... Nature, 1-9, 2024 | 2 | 2024 |
Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice EW Hollingsworth, TA Liu, SH Jacinto, CX Chen, JA Alcantara, EZ Kvon bioRxiv, 2023 | 2 | 2023 |