Bright and stable luminescent probes for target engagement profiling in live cells NC Payne, AS Kalyakina, K Singh, MA Tye, R Mazitschek Nature chemical biology 17 (11), 1168-1177, 2021 | 39 | 2021 |
Comparison of the redox chemistry of sulfur-and selenium-containing analogs of uracil NC Payne, A Geissler, A Button, AR Sasuclark, AL Schroll, EL Ruggles, ... Free Radical Biology and Medicine 104, 249-261, 2017 | 32 | 2017 |
A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader NC Payne, S Maksoud, BA Tannous, R Mazitschek Cell chemical biology 29 (8), 1333-1340. e5, 2022 | 21 | 2022 |
Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors NC Payne, R Mazitschek Cell Chemical Biology, 2022 | 15 | 2022 |
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance MA Tye, NC Payne, C Johansson, K Singh, SA Santos, L Fagbami, A Pant, ... Nature Communications 13 (1), 4976, 2022 | 14 | 2022 |
Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly RJ Adamson, NC Payne, SG Bartual, R Mazitschek, AN Bullock Free Radical Biology and Medicine 204, 215-225, 2023 | 13 | 2023 |
The prolyl-tRNA synthetase inhibitor halofuginone inhibits SARS-CoV-2 infection DR Sandoval, TM Clausen, C Nora, AP Cribbs, A Denardo, AE Clark, ... bioRxiv, 2021.03. 22.436522, 2021 | 13 | 2021 |
Can dimedone be used to study selenoproteins? An investigation into the reactivity of dimedone toward oxidized forms of selenocysteine NC Payne, DR Barber, EL Ruggles, RJ Hondal Protein Science 28 (1), 41-55, 2019 | 13 | 2019 |
Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma K Kurata, A James-Bott, MA Tye, L Yamamoto, MK Samur, YT Tai, ... Blood cancer journal 13 (1), 12, 2023 | 8 | 2023 |
Tiny Titans: Nanobodies as Powerful Tools for TR‐FRET Assay Development N Connor Payne, R Mazitschek Analysis & Sensing 2 (6), e202200020, 2022 | 8 | 2022 |
Rapid “mix and read” assay for scalable detection of SARS-CoV-2 antibodies in patient plasma H Yue, RP Nowak, D Overwijn, NC Payne, S Fischinger, C Atyeo, ... medRxiv, 2020.09. 01.20184101, 2020 | 6 | 2020 |
Inhibiting the Keap1/Nrf2 Protein‐Protein Interaction with Protein‐Like Polymers KP Carrow, HL Hamilton, MP Hopps, Y Li, B Qiao, NC Payne, ... Advanced Materials 36 (21), 2311467, 2024 | 5 | 2024 |
The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation S Ichikawa, NC Payne, W Xu, CF Chang, N Vallavoju, S Frome, ... Cell Chemical Biology, 2024 | 4 | 2024 |
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes X Xie, O Zhang, MJR Yeo, C Lee, SA Harry, L Paul, Y Li, NC Payne, ... bioRxiv, 2024.05. 14.593970, 2024 | 1 | 2024 |
Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology NC Payne, S Ichikawa, CM Woo, R Mazitschek STAR protocols 5 (2), 103129, 2024 | | 2024 |
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia ZC Rosenthal, DM Fass, NC Payne, A She, D Patnaik, KM Hennig, ... Scientific reports 14 (1), 9064, 2024 | | 2024 |
A lysate-based TR-FRET approach for the facile quantification of cellular drug concentration NC Payne, R Mazitschek | | 2024 |
Asymmetric Engagement of Dimeric CRL3KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes MJR Yeo, O Zhang, X Xie, E Nam, NC Payne, PM Gosavi, HS Kwok, I Iram, ... bioRxiv, 2024.05. 14.593897, 2024 | | 2024 |
Discovery of First-in-Class Small Molecule Inhibitors of the IRF4-PU. 1/Spi-B Interaction MP Agius, L Hevenor, NC Payne, R Mazitschek, HS Seo, S Dhe-Paganon, ... Blood 142, 3635, 2023 | | 2023 |
Tr-fret based assay for detection of antibodies in serological samples E Fischer, R Nowak, YUE Hong, D Overwijn, R Mazitschek, NC Payne US Patent App. 18/020,800, 2023 | | 2023 |