Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks B Shiotani, L Zou Molecular cell 33 (5), 547-558, 2009 | 471 | 2009 |
ATR autophosphorylation as a molecular switch for checkpoint activation S Liu, B Shiotani, M Lahiri, A Maréchal, A Tse, CCY Leung, JNM Glover, ... Molecular cell 43 (2), 192-202, 2011 | 316 | 2011 |
Human Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair T Yasuhara, R Kato, Y Hagiwara, B Shiotani, M Yamauchi, S Nakada, ... Cell 175 (2), 558-570. e11, 2018 | 301 | 2018 |
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response M Huang, JM Kim, B Shiotani, K Yang, L Zou, AD D'Andrea Molecular cell 39 (2), 259-268, 2010 | 166 | 2010 |
Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1 B Shiotani, HD Nguyen, P Håkansson, A Maréchal, A Tse, H Tahara, ... Cell reports 3 (5), 1651-1662, 2013 | 158 | 2013 |
Chk1 and Claspin potentiate PCNA ubiquitination XH Yang, B Shiotani, M Classon, L Zou Genes & development 22 (9), 1147-1152, 2008 | 140 | 2008 |
Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses N Chiba, V Comaills, B Shiotani, F Takahashi, T Shimada, K Tajima, ... Proceedings of the National Academy of Sciences 109 (8), 2760-2765, 2012 | 116 | 2012 |
ATR signaling at a glance B Shiotani, L Zou Journal of cell science 122 (3), 301-304, 2009 | 107 | 2009 |
Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor H Ogiwara, A Ui, B Shiotani, L Zou, A Yasui, T Kohno Carcinogenesis 34 (11), 2486-2497, 2013 | 90 | 2013 |
Frequent amplification of receptor tyrosine kinase genes in well-differentiated/dedifferentiated liposarcoma N Asano, A Yoshida, S Mitani, E Kobayashi, B Shiotani, M Komiyama, ... Oncotarget 8 (8), 12941, 2017 | 41 | 2017 |
SMARCA4 deficiency-associated heterochromatin induces intrinsic DNA replication stress and susceptibility to ATR inhibition in lung adenocarcinoma K Kurashima, H Kashiwagi, I Shimomura, A Suzuki, F Takeshita, ... NAR cancer 2 (2), zcaa005, 2020 | 34 | 2020 |
UV damage-induced phosphorylation of HBO1 triggers CRL4DDB2-mediated degradation to regulate cell proliferation R Matsunuma, H Niida, T Ohhata, K Kitagawa, S Sakai, C Uchida, ... Molecular and cellular biology, 2016 | 34 | 2016 |
PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA K Yano, R Takahashi, B Shiotani, J Abe, T Shidooka, Y Sudo, ... Journal of Biological Chemistry 297 (1), 2021 | 33 | 2021 |
Involvement of the ATR-and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1 B Shiotani, M Kobayashi, M Watanabe, K Yamamoto, T Sugimura, ... Molecular cancer research 4 (2), 125-133, 2006 | 29 | 2006 |
Tryptophan pyrolysis products, Trp-P-1 and Trp-P-2 induce apoptosis in primary cultured rat hepatocytes H Ashida, B Shiotani, H Adachi, T HASHIMOTO, K KANAZAWA, ... Bioscience, biotechnology, and biochemistry 62 (11), 2283-2287, 1998 | 26 | 1998 |
Developmental stage-specific expression and tissue distribution of pierisin-1, a guanine-specific ADP-ribosylating toxin, in Pieris rapae M Watanabe, T Nakano, B Shiotani, Y Matsushima-Hibiya, M Kiuchi, ... Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2004 | 20 | 2004 |
DNA-damaging carcinogen 3-amino-1, 4-dimethyl-5H-pyrido [4, 3-b] indole (Trp-P-1) induces apoptosis via caspase-9 in primary cultured rat hepatocytes B Shiotani, Y Nonaka, T Hashimoto, K Kihara, K Kanazawa, G Danno, ... Carcinogenesis 22 (5), 693-700, 2001 | 19 | 2001 |
3-Amino-1, 4-dimethyl-5H-pyrido [4, 3-b] indole (Trp-P-1) induces apoptosis in rat splenocytes and thymocytes by different mechanisms T Hashimoto, H Ashida, T Sano, T Furuyashiki, B Shiotani, K Kanazawa, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 457 (1 …, 2000 | 18 | 2000 |
DSE‐FRET: a new anticancer drug screening assay for DNA binding proteins T Miyagi, B Shiotani, R Miyoshi, T Yamamoto, T Oka, K Umezawa, ... Cancer Science 105 (7), 870-874, 2014 | 16 | 2014 |
CBP-93872 Inhibits NBS1-Mediated ATR Activation, Abrogating Maintenance of the DNA Double-Strand Break–Specific G2 Checkpoint T Hirokawa, B Shiotani, M Shimada, K Murata, Y Johmura, M Haruta, ... Cancer research 74 (14), 3880-3889, 2014 | 15 | 2014 |