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Jean Paul Chadarevian
Jean Paul Chadarevian
未知所在单位机构
在 uci.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
Nature communications 11 (1), 5370, 2020
2182020
Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease
C Claes, EP Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ...
Molecular neurodegeneration 16, 1-11, 2021
842021
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ...
Cell reports 39 (11), 2022
702022
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia
A Jairaman, A McQuade, A Granzotto, YJ Kang, JP Chadarevian, ...
Elife 11, e73021, 2022
392022
A chemical-genetic approach reveals the distinct roles of GSK3α and GSK3β in regulating embryonic stem cell fate
X Chen, R Wang, X Liu, Y Wu, T Zhou, Y Yang, A Perez, YC Chen, L Hu, ...
Developmental cell 43 (5), 563-576. e4, 2017
342017
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement
JP Chadarevian, SI Lombroso, GC Peet, J Hasselmann, C Tu, DE Marzan, ...
Journal of Experimental Medicine 220 (3), e20220857, 2022
312022
Cytoplasmic and nuclear TAZ exert distinct functions in regulating primed pluripotency
X Zhou, JP Chadarevian, B Ruiz, QL Ying
Stem cell reports 9 (3), 732-741, 2017
312017
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model
C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ...
Alzheimer's & Dementia 18 (10), 1765-1778, 2022
262022
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
JV Pluvinage, J Sun, C Claes, RA Flynn, MS Haney, T Iram, X Meng, ...
Science translational medicine 13 (622), eabg2919, 2021
222021
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
nature communications 14, 2023
202023
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: Therapeutic efficacy in PS19 mice
A Hovakimyan, T Antonyan, SK Shabestari, O Svystun, G Chailyan, ...
Scientific reports 9 (1), 15455, 2019
192019
Controlled release of stem cell secretome attenuates inflammatory response against implanted biomaterials
M Mohammadi, JC Luong, SM Rodriguez, R Cao, AE Wheeler, H Lau, ...
Advanced healthcare materials 9 (12), 1901874, 2020
122020
Autologous transplantation of skin-derived precursor cells in a porcine model
AL Thomas, JS Taylor, N Huynh, G Dubrovsky, JP Chadarevian, A Chen, ...
Journal of Pediatric Surgery 55 (1), 194-200, 2020
52020
CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model
JP Chadarevian, H Davtyan, SI Lombroso, FC Bennett, M Blurton-Jones
STAR protocols 4 (3), 102490, 2023
32023
Novel vaccine against pathological pyroglutamate-modified amyloid beta for prevention of Alzheimer’s disease
K Zagorski, O King, A Hovakimyan, I Petrushina, T Antonyan, G Chailyan, ...
International journal of molecular sciences 24 (12), 9797, 2023
22023
Microglia protect against age-associated brain pathologies
DAD Munro, N Bestard-Cuche, C McQuaid, A Chagnot, SK Shabestari, ...
Neuron, 2024
12024
Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy
JP Chadarevian, J Hasselmann, A Lahian, JK Capocchi, A Escobar, ...
Neuron, 2024
12024
ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia
A Granzotto, A McQuade, JP Chadarevian, H Davtyan, SL Sensi, I Parker, ...
bioRxiv, 2024
12024
Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease
N Rosenzweig, KL Kleemann, T Rust, M Carpenter, M Grucci, M Aronchik, ...
Nature Medicine, 1-14, 2024
2024
mRNA Vaccine for Alzheimer’s Disease: Pilot Study
A Hovakimyan, G Chilingaryan, O King, JK Capocchi, JP Chadarevian, ...
Vaccines 12 (6), 659, 2024
2024
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