Targeting the sonic hedgehog signaling pathway: review of smoothened and GLI inhibitors TK Rimkus, RL Carpenter, S Qasem, M Chan, HW Lo Cancers 8 (2), 22, 2016 | 622 | 2016 |
MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression LZ Liu, C Li, Q Chen, Y Jing, R Carpenter, Y Jiang, HF Kung, L Lai, ... PloS one 6 (4), e19139, 2011 | 593 | 2011 |
STAT3 target genes relevant to human cancers RL Carpenter, HW Lo Cancers 6 (2), 897-925, 2014 | 525 | 2014 |
Mechanisms regulating glioma invasion I Paw, RC Carpenter, K Watabe, W Debinski, HW Lo Cancer letters 362 (1), 1-7, 2015 | 348 | 2015 |
Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR‐199a/125b and DNA methylation J He, Q Xu, Y Jing, F Agani, X Qian, R Carpenter, Q Li, XR Wang, ... EMBO reports 13 (12), 1116-1122, 2012 | 148 | 2012 |
Hedgehog pathway and GLI1 isoforms in human cancer RL Carpenter, HW Lo Discovery medicine 13 (69), 105, 2012 | 137 | 2012 |
Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer F Xing, Y Liu, S Sharma, K Wu, MD Chan, HW Lo, RL Carpenter, ... Cancer research 76 (17), 4970-4980, 2016 | 123 | 2016 |
Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial–mesenchymal transition (EMT) of HER2-overexpressing breast … RL Carpenter, I Paw, MW Dewhirst, HW Lo Oncogene 34 (5), 546-557, 2015 | 118 | 2015 |
HSF1 as a cancer biomarker and therapeutic target RL Carpenter, Y Gökmen-Polar Current cancer drug targets 19 (7), 515-524, 2019 | 103 | 2019 |
Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer SR Sirkisoon, RL Carpenter, T Rimkus, A Anderson, A Harrison, ... Oncogene 37 (19), 2502-2514, 2018 | 101 | 2018 |
Repression of miR-143 mediates Cr (VI)–induced tumor angiogenesis via IGF-IR/IRS1/ERK/IL-8 pathway J He, X Qian, R Carpenter, Q Xu, L Wang, Y Qi, ZX Wang, LZ Liu, ... Toxicological Sciences 134 (1), 26-38, 2013 | 95 | 2013 |
Safety and tolerability of sonic hedgehog pathway inhibitors in cancer RL Carpenter, H Ray Drug Safety 42 (2), 263-279, 2019 | 94 | 2019 |
Regulation of apoptosis by HER2 in breast cancer RL Carpenter, HW Lo Journal of carcinogenesis & mutagenesis 2013 (Suppl 7), 2013 | 90 | 2013 |
EGFR and HER2 signaling in breast cancer brain metastasis SR Sirkisoon, RL Carpenter, T Rimkus, L Miller, L Metheny-Barlow, ... Frontiers in bioscience (Elite edition) 8, 245, 2016 | 84 | 2016 |
TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment SR Sirkisoon, RL Carpenter, T Rimkus, D Doheny, D Zhu, NR Aguayo, ... Oncogene 39 (1), 64-78, 2020 | 83 | 2020 |
Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1 RL Carpenter, Y Jiang, Y Jing, J He, Y Rojanasakul, LZ Liu, BH Jiang Biochemical and biophysical research communications 414 (3), 533-538, 2011 | 79 | 2011 |
Role and mechanism of arsenic in regulating angiogenesis LZ Liu, Y Jiang, RL Carpenter, Y Jing, SC Peiper, BH Jiang PloS one 6 (6), e20858, 2011 | 78 | 2011 |
STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3 W Han, RL Carpenter, X Cao, HW Lo Molecular carcinogenesis 52 (12), 959-969, 2013 | 77 | 2013 |
Endurance training slows breast tumor growth in mice by suppressing Treg cells recruitment to tumors A Hagar, Z Wang, S Koyama, JA Serrano, L Melo, S Vargas, R Carpenter, ... BMC cancer 19, 1-10, 2019 | 74 | 2019 |
The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth H Zhu, RL Carpenter, W Han, HW Lo Cancer letters 343 (1), 51-61, 2014 | 71 | 2014 |