Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85, 367-485, 2011 | 639 | 2011 |
Physiological pharmacokinetic analysis using population modeling and informative prior distributions A Gelman, F Bois, J Jiang Journal of the American Statistical Association 91 (436), 1400-1412, 1996 | 440 | 1996 |
Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 338 | 2017 |
Metabolomics in toxicology and preclinical research T Ramirez, M Daneshian, H Kamp, FY Bois, MR Clench, M Coen, ... Altex 30 (2), 209, 2013 | 251 | 2013 |
Joint modeling of survival and longitudinal non‐survival data: current methods and issues. Report of the DIA Bayesian joint modeling working group A Lawrence Gould, ME Boye, MJ Crowther, JG Ibrahim, G Quartey, ... Statistics in medicine 34 (14), 2181-2195, 2015 | 202 | 2015 |
PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals FY Bois, M Jamei, HJ Clewell Toxicology 278 (3), 256-267, 2010 | 202 | 2010 |
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 195 | 2013 |
Integrated Testing Strategies (ITS) for safety assessment. C Rovida, N Alépée, AM Api, DA Basketter, F y Bois, F Caloni, E Corsini, ... ALTEX-Alternatives to Animal Experimentations 32 (1), 25-40, 2015 | 174 | 2015 |
Statistical issues in toxicokinetic modeling: a Bayesian perspective P Bernillon, FY Bois Environmental Health Perspectives, 883-893, 2000 | 174 | 2000 |
Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches S Coecke, O Pelkonen, SB Leite, U Bernauer, JGM Bessems, FY Bois, ... Toxicology in vitro 27 (5), 1570-1577, 2013 | 159 | 2013 |
Characterizing uncertainty and variability in physiologically based pharmacokinetic models: state of the science and needs for research and implementation HA Barton, WA Chiu, R Woodrow Setzer, ME Andersen, AJ Bailer, ... Toxicological Sciences 99 (2), 395-402, 2007 | 157 | 2007 |
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA–EURL ECVAM ADME workshop JG Bessems, G Loizou, K Krishnan, HJ Clewell III, C Bernasconi, F Bois, ... Regulatory Toxicology and Pharmacology 68 (1), 119-139, 2014 | 147 | 2014 |
Bayesian-optimal design via interacting particle systems B Amzal, FY Bois, E Parent, CP Robert Journal of the American Statistical association 101 (474), 773-785, 2006 | 146 | 2006 |
Addressing human variability in next-generation human health risk assessments of environmental chemicals L Zeise, FY Bois, WA Chiu, D Hattis, I Rusyn, KZ Guyton Environmental health perspectives 121 (1), 23-31, 2013 | 142 | 2013 |
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 141 | 2015 |
Precision and sensitivity of pharmacokinetic models for cancer risk assessment: tetrachloroethylene in mice, rats, and humans FY Bois, L Zeise, TN Tozer Toxicology and applied pharmacology 102 (2), 300-315, 1990 | 137 | 1990 |
GNU MCSim: Bayesian statistical inference for SBML-coded systems biology models FY Bois Bioinformatics 25 (11), 1453-1454, 2009 | 136 | 2009 |
Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment: the first steps G Loizou, M Spendiff, HA Barton, J Bessems, FY Bois, MB d’Yvoire, ... Regulatory Toxicology and Pharmacology 50 (3), 400-411, 2008 | 127 | 2008 |
Toxicokinetic models and related tools in environmental risk assessment of chemicals A Grech, C Brochot, JL Dorne, N Quignot, FY Bois, R Beaudouin Science of the Total Environment 578, 1-15, 2017 | 120 | 2017 |
MCSim: a Monte Carlo simulation program FY Bois, DR Maszle Journal of Statistical Software 2, 1-60, 1997 | 117 | 1997 |