Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger PJ Schultheis, LL Clarke, P Meneton, ML Miller, M Soleimani, ... Nature genetics 19 (3), 282-285, 1998 | 913 | 1998 |
Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf M Flagella, LL Clarke, ML Miller, LC Erway, RA Giannella, A Andringa, ... Journal of Biological Chemistry 274 (38), 26946-26955, 1999 | 458 | 1999 |
Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male … GW Okunade, ML Miller, GJ Pyne, RL Sutliff, KT O'Connor, JC Neumann, ... Journal of Biological Chemistry 279 (32), 33742-33750, 2004 | 395 | 2004 |
Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2 PJ Kozel, RA Friedman, LC Erway, EN Yamoah, LH Liu, T Riddle, JJ Duffy, ... Journal of Biological Chemistry 273 (30), 18693-18696, 1998 | 386 | 1998 |
Oral exposure to benzo [a] pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation S Uno, TP Dalton, S Derkenne, CP Curran, ML Miller, HG Shertzer, ... Molecular pharmacology 65 (5), 1225-1237, 2004 | 379 | 2004 |
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis TP Dalton, L He, B Wang, ML Miller, L Jin, KF Stringer, X Chang, ... Proceedings of the National Academy of Sciences 102 (9), 3401-3406, 2005 | 334 | 2005 |
Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl− cotransporter of the distal convoluted tubule PJ Schultheis, JN Lorenz, P Meneton, ML Nieman, TM Riddle, M Flagella, ... Journal of Biological Chemistry 273 (44), 29150-29155, 1998 | 317 | 1998 |
Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. PJ Schultheis, LL Clarke, P Meneton, M Harline, GP Boivin, ... The Journal of clinical investigation 101 (6), 1243-1253, 1998 | 291 | 1998 |
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures SM Bell, CM Schreiner, PJ Schultheis, ML Miller, RL Evans, CV Vorhees, ... American Journal of Physiology-Cell Physiology 276 (4), C788-C795, 1999 | 287 | 1999 |
Oral benzo [a] pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and … S Uno, TP Dalton, N Dragin, CP Curran, S Derkenne, ML Miller, ... Molecular pharmacology 69 (4), 1103-1114, 2006 | 264 | 2006 |
Stomachs of mice lacking the gastric H, K-ATPase α-subunit have achlorhydria, abnormal parietal cells, and ciliated metaplasia Z Spicer, ML Miller, A Andringa, TM Riddle, JJ Duffy, T Doetschman, ... Journal of Biological Chemistry 275 (28), 21555-21565, 2000 | 221 | 2000 |
Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome JN Lorenz, NR Baird, LM Judd, WT Noonan, A Andringa, T Doetschman, ... Journal of Biological Chemistry 277 (40), 37871-37880, 2002 | 209 | 2002 |
Phenotypes of SERCA and PMCA knockout mice V Prasad, GW Okunade, ML Miller, GE Shull Biochemical and biophysical research communications 322 (4), 1192-1203, 2004 | 203 | 2004 |
Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO 3-cotransporter LR Gawenis, EM Bradford, V Prasad, JN Lorenz, JE Simpson, LL Clarke, ... Journal of Biological Chemistry 282 (12), 9042-9052, 2007 | 181 | 2007 |
Hepatocyte‐specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure Y Chen, Y Yang, ML Miller, D Shen, HG Shertzer, KF Stringer, B Wang, ... Hepatology 45 (5), 1118-1128, 2007 | 178 | 2007 |
Mice with a targeted disruption of the AE2 Cl−/HCO 3− exchanger are achlorhydric LR Gawenis, C Ledoussal, LM Judd, V Prasad, SL Alper, A Stuart-Tilley, ... Journal of Biological Chemistry 279 (29), 30531-30539, 2004 | 168 | 2004 |
Ligand‐specific function of transforming growth factor beta in epithelial‐mesenchymal transition in heart development M Azhar, RB Runyan, C Gard, LP Sanford, ML Miller, A Andringa, ... Developmental dynamics 238 (2), 431-442, 2009 | 157 | 2009 |
Loss of the Atp2c1 secretory pathway Ca2+-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in … GW Okunade, ML Miller, M Azhar, A Andringa, LP Sanford, T Doetschman, ... Journal of Biological Chemistry 282 (36), 26517-26527, 2007 | 152 | 2007 |
Dioxin exposure is an environmental risk factor for ischemic heart disease TP Dalton, JK Kerzee, B Wang, M Miller, MZ Dieter, JN Lorenz, ... Cardiovascular toxicology 1, 285-298, 2001 | 149 | 2001 |
Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco (endo) plasmic reticulum Ca2+-ATPase isoform 3 LH Liu, RJ Paul, RL Sutliff, ML Miller, JN Lorenz, RYK Pun, JJ Duffy, ... Journal of Biological Chemistry 272 (48), 30538-30545, 1997 | 140 | 1997 |