Microglial activation and tau propagate jointly across Braak stages TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ... Nature medicine 27 (9), 1592-1599, 2021 | 303 | 2021 |
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ... JAMA neurology 78 (12), 1471-1483, 2021 | 254 | 2021 |
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ... JAMA neurology 77 (4), 470-479, 2020 | 195 | 2020 |
18F-MK-6240 PET for early and late detection of neurofibrillary tangles TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ... Brain 143 (9), 2818-2830, 2020 | 174 | 2020 |
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ... Alzheimer's & dementia 16 (1), 192-199, 2020 | 131 | 2020 |
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ... Nature aging 2 (6), 526-535, 2022 | 120 | 2022 |
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease B Bellaver, G Povala, PCL Ferreira, JP Ferrari-Souza, DT Leffa, ... Nature medicine 29 (7), 1775-1781, 2023 | 89 | 2023 |
Association of phosphorylated tau biomarkers with amyloid positron emission tomography vs tau positron emission tomography J Therriault, M Vermeiren, S Servaes, C Tissot, NJ Ashton, AL Benedet, ... JAMA neurology 80 (2), 188-199, 2023 | 82 | 2023 |
Determining amyloid-β positivity using 18F-AZD4694 PET imaging J Therriault, AL Benedet, TA Pascoal, M Savard, NJ Ashton, M Chamoun, ... Journal of Nuclear Medicine 62 (2), 247-252, 2021 | 80 | 2021 |
APOEε4 potentiates the relationship between amyloid-β and tau pathologies J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Savard, ... Molecular psychiatry 26 (10), 5977-5988, 2021 | 69 | 2021 |
Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s disease JP Ferrari-Souza, PCL Ferreira, B Bellaver, C Tissot, YT Wang, DT Leffa, ... Molecular psychiatry 27 (11), 4781-4789, 2022 | 63 | 2022 |
Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages TA Pascoal, AL Benedet, DL Tudorascu, J Therriault, S Mathotaarachchi, ... Brain 144 (11), 3517-3528, 2021 | 63 | 2021 |
Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, APOE ε4, and Cognitive Impairment J Therriault, TA Pascoal, AL Benedet, C Tissot, M Savard, M Chamoun, ... Neurology 96 (7), e975-e985, 2021 | 52 | 2021 |
Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer disease pathology NJ Ashton, WS Brum, G Di Molfetta, AL Benedet, B Arslan, E Jonaitis, ... JAMA neurology 81 (3), 255-263, 2024 | 49 | 2024 |
Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease T Terada, J Therriault, MSP Kang, M Savard, TA Pascoal, F Lussier, ... Molecular neurodegeneration 16, 1-12, 2021 | 47 | 2021 |
Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer’s disease C Tissot, A L. Benedet, J Therriault, TA Pascoal, FZ Lussier, ... Alzheimer's Research & Therapy 13, 1-11, 2021 | 45 | 2021 |
Association of plasma P-tau181 with memory decline in non-demented adults J Therriault, AL Benedet, TA Pascoal, FZ Lussier, C Tissot, TK Karikari, ... Brain Communications 3 (3), fcab136, 2021 | 39 | 2021 |
Comparing tau status determined via plasma pTau181, pTau231 and [18F] MK6240 tau-PET C Tissot, J Therriault, P Kunach, AL Benedet, TA Pascoal, NJ Ashton, ... EBioMedicine 76, 2022 | 38 | 2022 |
Topographic distribution of amyloid-β, tau, and atrophy in patients with behavioral/dysexecutive Alzheimer disease J Therriault, TA Pascoal, M Savard, AL Benedet, M Chamoun, C Tissot, ... Neurology 96 (1), e81-e92, 2021 | 37 | 2021 |
A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases WS Brum, NC Cullen, S Janelidze, NJ Ashton, ER Zimmer, J Therriault, ... Nature Aging 3 (9), 1079-1090, 2023 | 32 | 2023 |