| Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases C Paradis-Bleau, M Markovski, T Uehara, TJ Lupoli, S Walker, DE Kahne, ... Cell 143 (7), 1110-1120, 2010 | 351 | 2010 |
| Transpeptidase-Mediated Incorporation of d-Amino Acids into Bacterial Peptidoglycan TJ Lupoli, H Tsukamoto, EH Doud, TSA Wang, S Walker, D Kahne Journal of the American Chemical Society 133 (28), 10748-10751, 2011 | 159 | 2011 |
| Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis MD Lebar, JM May, AJ Meeske, SA Leiman, TJ Lupoli, H Tsukamoto, ... Journal of the American Chemical Society 136 (31), 10874-10877, 2014 | 121 | 2014 |
| Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells J Vaubourgeix, G Lin, N Dhar, N Chenouard, X Jiang, H Botella, T Lupoli, ... Cell host & microbe 17 (2), 178-190, 2015 | 101 | 2015 |
| Lipoprotein Activators Stimulate Escherichia coli Penicillin-Binding Proteins by Different Mechanisms TJ Lupoli, MD Lebar, M Markovski, T Bernhardt, D Kahne, S Walker Journal of the American Chemical Society 136 (1), 52-55, 2014 | 94 | 2014 |
| ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB H Yu, TJ Lupoli, A Kovach, X Meng, G Zhao, CF Nathan, H Li Proceedings of the National Academy of Sciences 115 (41), E9560-E9569, 2018 | 77 | 2018 |
| Haloduracin α binds the peptidoglycan precursor lipid II with 2: 1 stoichiometry TJ Oman, TJ Lupoli, TSA Wang, D Kahne, S Walker, WA Van Der Donk Journal of the American Chemical Society 133 (44), 17544-17547, 2011 | 74 | 2011 |
| Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division Y Rebets, T Lupoli, Y Qiao, K Schirner, R Villet, D Hooper, D Kahne, ... ACS chemical biology 9 (2), 459-467, 2014 | 70 | 2014 |
| Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II MD Lebar, TJ Lupoli, H Tsukamoto, JM May, S Walker, D Kahne Journal of the American Chemical Society 135 (12), 4632-4635, 2013 | 68 | 2013 |
| Targeting the proteostasis network for mycobacterial drug discovery TJ Lupoli, J Vaubourgeix, K Burns-Huang, B Gold ACS infectious diseases 4 (4), 478-498, 2018 | 66 | 2018 |
| Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK TJ Lupoli, A Fay, C Adura, MS Glickman, CF Nathan Proceedings of the National Academy of Sciences 113 (49), E7947-E7956, 2016 | 47 | 2016 |
| Non-proteinogenic amino acids in lacticin 481 analogues result in more potent inhibition of peptidoglycan transglycosylation PJ Knerr, TJ Oman, CV Garcia De Gonzalo, TJ Lupoli, S Walker, ... ACS chemical biology 7 (11), 1791-1795, 2012 | 45 | 2012 |
| Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity M Markovski, JL Bohrhunter, TJ Lupoli, T Uehara, S Walker, DE Kahne, ... Proceedings of the National Academy of Sciences 113 (17), 4788-4793, 2016 | 40 | 2016 |
| Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A C Leimkuhler, M Fridman, T Lupoli, S Walker, CT Walsh, D Kahne Journal of the American Chemical Society 129 (34), 10546-10550, 2007 | 40 | 2007 |
| Studying a cell division amidase using defined peptidoglycan substrates TJ Lupoli, T Taniguchi, TS Wang, DL Perlstein, S Walker, DE Kahne Journal of the American Chemical Society 131 (51), 18230-18231, 2009 | 35 | 2009 |
| Chemoenzymatic formation of novel aminocoumarin antibiotics by the enzymes CouN1 and CouN7 M Fridman, CJ Balibar, T Lupoli, D Kahne, CT Walsh, ... Biochemistry 46 (28), 8462-8471, 2007 | 34 | 2007 |
| Primer preactivation of peptidoglycan polymerases TSA Wang, TJ Lupoli, Y Sumida, H Tsukamoto, Y Wu, Y Rebets, ... Journal of the American Chemical Society 133 (22), 8528-8530, 2011 | 33 | 2011 |
| Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress A Harnagel, L Lopez Quezada, SW Park, C Baranowski, K Kieser, X Jiang, ... Molecular microbiology 115 (2), 272-289, 2021 | 19 | 2021 |
| An allosteric inhibitor of bacterial Hsp70 chaperone potentiates antibiotics and mitigates resistance J Hosfelt, A Richards, M Zheng, C Adura, B Nelson, A Yang, A Fay, ... Cell chemical biology 29 (5), 854-869. e9, 2022 | 14 | 2022 |
| Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Mycobacterium tuberculosis Bind Multiple Protein Families and … L Lopez Quezada, R Smith, TJ Lupoli, Z Edoo, X Li, B Gold, J Roberts, ... Frontiers in Microbiology 11, 1248, 2020 | 14 | 2020 |
