Mechanisms of ADC toxicity and strategies to increase ADC tolerability TD Nguyen, BM Bordeau, JP Balthasar Cancers 15 (3), 713, 2023 | 55 | 2023 |
Payload-binding Fab fragments increase the therapeutic index of MMAE antibody–drug conjugates BM Bordeau, TD Nguyen, JR Polli, P Chen, JP Balthasar Molecular cancer therapeutics 22 (4), 459-470, 2023 | 10 | 2023 |
Development and evaluation of competitive inhibitors of trastuzumab-HER2 binding to bypass the binding-site barrier BM Bordeau, L Abuqayyas, TD Nguyen, P Chen, JP Balthasar Frontiers in pharmacology 13, 837744, 2022 | 9 | 2022 |
Use of Payload Binding Selectivity Enhancers to Improve Therapeutic Index of Maytansinoid–Antibody–Drug Conjugates TD Nguyen, BM Bordeau, JP Balthasar Molecular cancer therapeutics 22 (11), 1332-1342, 2023 | 3 | 2023 |
Half-Life Extension and Biodistribution Modulation of Biotherapeutics via Red Blood Cell Hitch-Hiking with Novel Anti-Band 3 Single-Domain Antibodies TD Nguyen, BM Bordeau, Y Zhang, AG Mattle, JP Balthasar Int. J. Mol. Sci. 24 (1), 475, 2023 | 3 | 2023 |
Compositions and methods for reducing off-target toxicity of antibody drug conjugates JP Balthasar, BM Bordeau, TD Nguyen, JR Polli EP Patent App. 20895870.2, 2023 | | 2023 |
Anti- monomethyl Auristatin (mmae) Antibodies and Antibody Fragments JP Balthasar, BM Bordeau, TD Nguyen, JR Polli WO Patent App. PCT/US2023/072,852, 2023 | | 2023 |
Anti-Camptothecin Antibodies and Antibody Fragments JP Balthasar, BM Bordeau, TD Nguyen US Patent App. 63/581,647, 2023 | | 2023 |
SLC4A1 (Band 3) Binding Single Domain Antibodies for Increased Blood Retention JP Balthasar, BM Bordeau, TD Nguyen US Patent App. 63/520,689, 2023 | | 2023 |
Compositions and Methods for Reducing Off-Target Toxicity of Antibody Drug Conjugates JP Balthasar, BM Bordeau, TD Nguyen, JR Polli US Patent App. 17/782,549, 2022 | | 2022 |
Anti- monomethyl Auristatin (mmae) Antibodies and Antibody Fragments JP Balthasar, BM Bordeau, TD Nguyen, JR Polli US Patent App. 63/373,367, 2022 | | 2022 |
Development and Optimization of Antibody-Drug Conjugates for the Treatment of Acute Myeloid Leukemia TD Nguyen State University of New York at Buffalo, 2022 | | 2022 |
Compositions and Methods for Reducing Off-Target Toxicity of Antibody Drug Conjugates JP Balthasar, BM Bordeau, TD Nguyen, JR Polli WO Patent App. PCT/US2020/063,453, 2020 | | 2020 |
Compositions and Methods for Reducing Off-Target Toxicity of Antibody Drug Conjugates JP Balthasar, BM Bordeau, TD Nguyen, JR Polli US Patent App. 62/943,358, 2019 | | 2019 |