| CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease) SL Eaton, C Proudfoot, SG Lillico, P Skehel, RA Kline, K Hamer, ... Scientific reports 9 (1), 9891, 2019 | 58 | 2019 |
| Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases RA Kline, KA Kaifer, EY Osman, F Carella, A Tiberi, J Ross, G Pennetta, ... PLoS genetics 13 (3), e1006680, 2017 | 43 | 2017 |
| Pre-natal manifestation of systemic developmental abnormalities in spinal muscular atrophy AAL Motyl, KME Faller, EJN Groen, RA Kline, SL Eaton, LM Ledahawsky, ... Human Molecular Genetics 29 (16), 2674-2683, 2020 | 34 | 2020 |
| AAV9-Stathmin1 gene delivery improves disease phenotype in an intermediate mouse model of spinal muscular atrophy E Villalón, RA Kline, CE Smith, ZC Lorson, EY Osman, S O’Day, ... Human molecular genetics 28 (22), 3742-3754, 2019 | 29 | 2019 |
| Synaptic proteomics reveal distinct molecular signatures of cognitive change and C9ORF72 repeat expansion in the human ALS cortex ZI Laszlo, N Hindley, A Sanchez Avila, RA Kline, SL Eaton, DJ Lamont, ... Acta neuropathologica communications 10 (1), 156, 2022 | 23 | 2022 |
| Applying modern Omic technologies to the neuronal ceroid lipofuscinoses RA Kline, TM Wishart, K Mills, WE Heywood Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (9), 165498, 2020 | 21 | 2020 |
| Selective vulnerability in neuronal populations in nmd/SMARD1 mice E Villalón, M Shababi, R Kline, ZC Lorson, KM Florea, CL Lorson Human Molecular Genetics 27 (4), 679-690, 2018 | 18 | 2018 |
| Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice RA Kline, KN Dissanayake, ML Hurtado, NW Martínez, A Ahl, AJ Mole, ... Neurobiology of disease 130, 104496, 2019 | 16* | 2019 |
| The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo LM Ledahawsky, ME Terzenidou, R Edwards, RA Kline, LC Graham, ... The FEBS Journal 289 (13), 3894-3914, 2022 | 10 | 2022 |
| Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease HR Nelvagal, ML Hurtado, SL Eaton, RA Kline, DJ Lamont, MS Sands, ... Scientific reports 10 (1), 15157, 2020 | 10 | 2020 |
| Quantitative imaging of tissue sections using infrared scanning technology SL Eaton, E Cumyn, D King, RA Kline, SM Carpanini, J Del‐Pozo, ... Journal of Anatomy 228 (1), 203-213, 2016 | 10 | 2016 |
| Intraperitoneal delivery of a novel drug‐like compound improves disease severity in severe and intermediate mouse models of Spinal Muscular Atrophy EY Osman, A Rietz, RA Kline, JJ Cherry, KJ Hodgetts, CL Lorson, ... Scientific Reports 9 (1), 1633, 2019 | 8 | 2019 |
| Motor unit recovery following Smn restoration in mouse models of spinal muscular atrophy LH Comley, RA Kline, AK Thomson, V Woschitz, EV Landeros, EY Osman, ... Human Molecular Genetics 31 (18), 3107-3119, 2022 | 7 | 2022 |
| The proteome signatures of fibroblasts from patients with severe, intermediate and mild spinal muscular atrophy show limited overlap SJ Brown, RA Kline, SA Synowsky, SL Shirran, I Holt, KA Sillence, ... Cells 11 (17), 2624, 2022 | 5 | 2022 |
| An optimized comparative proteomic approach as a tool in neurodegenerative disease research RA Kline, L Lößlein, D Kurian, J Aguilar Martí, SL Eaton, FA Court, ... Cells 11 (17), 2653, 2022 | 2 | 2022 |
| Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation MS Arrázola, M Lira, G Quiroz, S Iqbal, SL Eaton, RA Kline, DJ Lamont, ... bioRxiv, 2021.11. 10.468052, 2021 | 2 | 2021 |
| Court, FA; Gillingwater, TH; Wishart, TM An Optimized Comparative Proteomic Approach as a Tool in Neurodegenerative Disease Research. Cells 2022, 11, 2653 RA Kline, L Lößlein, D Kurian, J Aguilar Martí, SL Eaton s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022 | 1 | 2022 |
| ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet in male mice E Villalobos, A Miguelez-Crespo, RA Morgan, L Ivatt, M Paul, JP Simpson, ... The Journal of Endocrinology 262 (2), 2024 | | 2024 |
| ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet in male mice E Villalobos, A Miguelez-Crespo, RA Morgan, L Ivatt, M Paul, JP Simpson, ... Journal of Endocrinology 262 (2), 2024 | | 2024 |
| Refining and applying comparative proteomics workflows to uncover novel regulators of neuronal stability between childhood and adult-onset degenerative diseases RA Kline The University of Edinburgh, 2022 | | 2022 |
