关注
Sheeba Jacob
Sheeba Jacob
Post doctoral Fellow, Virginia Commonwealth University, VA
在 vcu.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
MYCN-Amplified Neuroblastoma Is Addicted to Iron and Vulnerable to Inhibition of the System Xc-/Glutathione Axis
KV Floros, JY Cai, S Jacob, R Kurupi, CK Fairchild, M Shende, CM Coon, ...
Cancer research 81 (7), 1896-1908, 2021
962021
Increased Synthesis of MCL-1 Protein Underlies Initial Survival of EGFR-Mutant Lung Cancer to EGFR Inhibitors and Provides a Novel Drug Target
KA Song, Y Hosono, C Turner, S Jacob, TL Lochmann, Y Murakami, ...
Clinical Cancer Research 24 (22), 5658-5672, 2018
592018
Long circulating PEGylated PLGA nanoparticles of cytarabine for targeting leukemia
KS Yadav, S Jacob, G Sachdeva, K Chuttani, AK Mishra, KK Sawant
Journal of microencapsulation 28 (8), 729-742, 2011
442011
Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer
S Jacob, S Nayak, G Fernandes, RS Barai, S Menon, UK Chaudhari, ...
Endocr Relat Cancer 21 (3), 473-486, 2014
412014
The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity
DAR Heisey, TL Lochmann, KV Floros, CM Coon, KM Powell, S Jacob, ...
Clinical Cancer Research 25 (5), 1664-1675, 2019
362019
Intracellular delivery of etoposide loaded biodegradable nanoparticles: cytotoxicity and cellular uptake studies
KS Yadav, S Jacob, G Sachdeva, KK Sawant
Journal of Nanoscience and Nanotechnology 11 (8), 6657-6667, 2011
282011
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
J Cai, S Jacob, R Kurupi, KM Dalton, C Coon, P Greninger, RK Egan, ...
Cell reports 40 (4), 2022
172022
Venetoclax-based Rational Combinations are Effective in Models of MYCN-amplified Neuroblastoma
KM Dalton, K Krytska, TL Lochmann, R Sano, C Casey, A D'Aulerio, ...
Molecular cancer therapeutics 20 (8), 1400-1411, 2021
142021
A triad of telomerase, androgen receptor and early growth response 1 in prostate cancer cells
S Jacob, S Nayak, R Kakar, UK Chaudhari, D Joshi, BR Vundinti, ...
Cancer Biology & Therapy 17 (4), 439-448, 2016
142016
Differential expression of calreticulin, a reticuloplasmin in primate endometrium
T Parmar, S Nimbkar-Joshi, RR Katkam, S Gadkar-Sable, U Chaudhari, ...
Human reproduction 24 (9), 2205-2216, 2009
142009
Endometrial epithelial cell modifications in response to embryonic signals in bonnet monkeys (Macaca radiata)
S Nimbkar-Joshi, RR Katkam, UK Chaudhari, S Jacob, DD Manjramkar, ...
Histochemistry and cell biology 138 (2), 289-304, 2012
132012
Pharmaceutical interference of the EWS-FLI1–driven transcriptome by cotargeting H3K27ac and RNA polymerase activity in Ewing sarcoma
DAR Heisey, S Jacob, TL Lochmann, R Kurupi, MS Ghotra, ML Calbert, ...
Molecular Cancer Therapeutics 20 (10), 1868-1879, 2021
122021
Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors
KV Floros, S Jacob, R Kurupi, CK Fairchild, B Hu, M Puchalapalli, ...
Cell Death & Disease 12 (2), 179, 2021
122021
Unmasking Bcl-2 addiction in synovial sarcoma by overcoming low Noxa
CK Fairchild Jr, KV Floros, S Jacob, CM Coon, M Puchalapalli, B Hu, ...
Cancers 13 (10), 2310, 2021
72021
Pharmacologic inhibition of SHP2 blocks both PI3K and MEK signaling in low-epiregulin HNSCC via GAB1
R Kurupi, KV Floros, S Jacob, AT Chawla, J Cai, B Hu, M Puchalapalli, ...
Cancer research communications 2 (9), 1061-1074, 2022
42022
Evaluation of combined BCL-2/MCL-1 inhibition as a therapeutic approach for synovial sarcoma.
CK Fairchild, K Floros, S Jacob, C Coon, M Puchalapalli, B Hu, ...
Journal of Clinical Oncology 38 (15_suppl), e23561-e23561, 2020
42020
Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models
S Jacob, TH Turner, J Cai, KV Floros, AK Yu, CM Coon, R Khatri, ...
PNAS nexus 1 (5), pgac232, 2022
22022
Nanomaterials physics: A critical review
KS Yadav, S Jacob, AM Pethe
Photophysics and Nanophysics in Therapeutics, 207-216, 2022
22022
R9: A novel NuRD complex inhibitor for targeted therapy in triple negative breast cancer (TNBC)
K Zhang, S Jacob, M Dozmorov, I Babic, E Nurmemmedov, AC Faber
Cancer Research 84 (6_Supplement), 5976-5976, 2024
2024
Epithelial-mesenchymal transition and resistance to EGFR inhibitors
S Jacob, R Kurupi, AC Faber
Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC, 105-124, 2023
2023
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