Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα DR Alessi, SR James, CP Downes, AB Holmes, PRJ Gaffney, CB Reese, ... Current biology 7 (4), 261-269, 1997 | 3949 | 1997 |
Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase B D Stokoe, LR Stephens, T Copeland, PRJ Gaffney, CB Reese, GF Painter, ... Science 277 (5325), 567-570, 1997 | 1642 | 1997 |
Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B L Stephens, K Anderson, D Stokoe, H Erdjument-Bromage, GF Painter, ... Science 279 (5351), 710-714, 1998 | 1434 | 1998 |
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase DR Alessi, M Deak, A Casamayor, FB Caudwell, N Morrice, DG Norman, ... Current biology 7 (10), 776-789, 1997 | 998 | 1997 |
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2 A Balendran, A Casamayor, M Deak, A Paterson, P Gaffney, R Currie, ... Current Biology 9 (8), 393-404, 1999 | 597 | 1999 |
PtdIns (3) P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox CD Ellson, S Gobert-Gosse, KE Anderson, K Davidson, ... Nature cell biology 3 (7), 679-682, 2001 | 488 | 2001 |
Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system S Gharbi, P Gaffney, A Yang, MJ Zvelebil, R Cramer, MD Waterfield, ... Molecular & Cellular Proteomics 1 (2), 91-98, 2002 | 376 | 2002 |
Protein sulfenation as a redox sensor: proteomics studies using a novel biotinylated dimedone analogue RL Charles, E Schroder, G May, P Free, PRJ Gaffney, R Wait, S Begum, ... Molecular & Cellular Proteomics 6 (9), 1473-1484, 2007 | 221 | 2007 |
Proteomic analysis of redox‐and ErbB2‐dependent changes in mammary luminal epithelial cells using cysteine‐and lysine‐labelling two‐dimensional difference gel electrophoresis HL Chan, S Gharbi, PR Gaffney, R Cramer, MD Waterfield, JF Timms Proteomics 5 (11), 2908-2926, 2005 | 111 | 2005 |
Roll-to-roll dip coating of three different PIMs for Organic Solvent Nanofiltration M Cook, PRJ Gaffney, LG Peeva, AG Livingston Journal of membrane science 558, 52-63, 2018 | 97 | 2018 |
Proteomic analysis of UVC irradiation-induced damage of plasma proteins: Serum amyloid P component as a major target of photolysis HL Chan, PR Gaffney, MD Waterfield, H Anderle, HP Matthiessen, ... FEBS letters 580 (13), 3229-3236, 2006 | 82 | 2006 |
Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving R Dong, R Liu, PRJ Gaffney, M Schaepertoens, P Marchetti, CM Williams, ... Nature chemistry 11 (2), 136-145, 2019 | 79 | 2019 |
Why Are Silyl Ethers Conformationally Different from Alkyl Ethers? Chair− Chair Conformational Equilibria in Silyloxycyclohexanes and Their Dependence on the Substituents on … CH Marzabadi, JE Anderson, J Gonzalez-Outeirino, PRJ Gaffney, ... Journal of the American Chemical Society 125 (49), 15163-15173, 2003 | 70 | 2003 |
Regulation of the hypoxia-dependent plasminogen activator inhibitor 1 expression by MAP kinases T Kietzmann, K Jungermann, A Görlach Thrombosis and haemostasis 89 (04), 666-673, 2003 | 67 | 2003 |
Organic solvent nanofiltration (OSN): A new technology platform for liquid-phase oligonucleotide synthesis (LPOS) JF Kim, PRJ Gaffney, IB Valtcheva, G Williams, AM Buswell, MS Anson, ... Organic Process Research & Development 20 (8), 1439-1452, 2016 | 60 | 2016 |
Iterative synthesis of monodisperse PEG homostars and linear heterobifunctional PEG G Székely, M Schaepertoens, PRJ Gaffney, AG Livingston Polymer Chemistry 5 (3), 694-697, 2014 | 54 | 2014 |
Synthesis of orthogonally protected lanthionines MF Mohd Mustapa, R Harris, N Bulic-Subanovic, SL Elliott, S Bregant, ... The Journal of Organic Chemistry 68 (21), 8185-8192, 2003 | 52 | 2003 |
Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate S Furse, NJ Brooks, AM Seddon, R Woscholski, RH Templer, EW Tate, ... Soft Matter 8 (11), 3090-3093, 2012 | 51 | 2012 |
Beyond PEG2000: synthesis and functionalisation of monodisperse PEGylated homostars and clickable bivalent polyethyleneglycols G Székely, M Schaepertoens, PRJ Gaffney, AG Livingston Chemistry–A European Journal 20 (32), 10038-10051, 2014 | 50 | 2014 |
Synthesis of naturally occurring phosphatidylinositol 3, 4, 5-trisphosphate [PtdIns (3, 4, 5) P 3] and its diastereoisomers PRJ Gaffney, CB Reese Journal of the Chemical Society, Perkin Transactions 1, 192-205, 2001 | 50 | 2001 |