GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1 E Harjes, S Harjes, S Wohlgemuth, KH Müller, E Krieger, C Herrmann, ... Structure 14 (5), 881-888, 2006 | 83 | 2006 |
Impact of H216 on the DNA binding and catalytic activities of the HIV restriction factor APOBEC3G S Harjes, WC Solomon, M Li, KM Chen, E Harjes, RS Harris, H Matsuo Journal of virology 87 (12), 7008-7014, 2013 | 62 | 2013 |
The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate binding S Harjes, P Bayer, AJ Scheidig Journal of molecular biology 347 (3), 623-635, 2005 | 55 | 2005 |
Inhibiting APOBEC3 activity with single-stranded DNA containing 2′-deoxyzebularine analogues MV Kvach, FM Barzak, S Harjes, HAM Schares, GB Jameson, AM Ayoub, ... Biochemistry 58 (5), 391-400, 2018 | 51 | 2018 |
TMAO and other organic osmolytes in the muscles of amphipods (Crustacea) from shallow and deep water of Lake Baikal I Zerbst-Boroffka, RM Kamaltynow, S Harjes, E Kinne-Saffran, J Gross Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2005 | 43 | 2005 |
Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2′-deoxyzebularine FM Barzak, S Harjes, MV Kvach, HM Kurup, GB Jameson, VV Filichev, ... Organic & biomolecular chemistry 17 (43), 9435-9441, 2019 | 35 | 2019 |
Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA MV Kvach, FM Barzak, S Harjes, HAM Schares, HM Kurup, KF Jones, ... ChemBioChem 21 (7), 1028-1035, 2020 | 23 | 2020 |
NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate S Harjes, GB Jameson, VV Filichev, PJB Edwards, E Harjes Nucleic acids research 45 (9), 5602-5613, 2017 | 22 | 2017 |
Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A S Harjes, HM Kurup, AE Rieffer, M Bayarjargal, J Filitcheva, Y Su, TK Hale, ... Nature communications 14 (1), 6382, 2023 | 14 | 2023 |
Expression, purification and crystallization of human 3′-phosphoadenosine-5′-phosphosulfate synthetase 1 S Harjes, A Scheidig, P Bayer Acta Crystallographica Section D: Biological Crystallography 60 (2), 350-352, 2004 | 12 | 2004 |
Design, synthesis, and evaluation of a cross-linked oligonucleotide as the first nanomolar inhibitor of APOBEC3A HM Kurup, MV Kvach, S Harjes, FM Barzak, GB Jameson, E Harjes, ... Biochemistry 61 (22), 2568-2578, 2022 | 11 | 2022 |
Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A HM Kurup, MV Kvach, S Harjes, GB Jameson, E Harjes, VV Filichev Organic & Biomolecular Chemistry 21 (24), 5117-5128, 2023 | 6 | 2023 |
Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2 E Harjes, GB Jameson, YH Tu, N Burr, TS Loo, AK Goroncy, PJB Edwards, ... FEBS letters 595 (3), 324-340, 2021 | 4 | 2021 |
TonB–a mediator of iron uptake in bacteria P Bayer, S Harjes Trends in Biochemical Sciences 26 (8), 472, 2001 | 4 | 2001 |
Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity FM Barzak, TM Ryan, N Mohammadzadeh, S Harjes, MV Kvach, ... Viruses 14 (9), 1974, 2022 | 3 | 2022 |
Synthesis of 1, 4-azaphosphinine nucleosides and evaluation as inhibitors of human cytidine deaminase and APOBEC3A MV Kvach, S Harjes, HM Kurup, GB Jameson, E Harjes, VV Filichev Beilstein Journal of Organic Chemistry 20 (1), 1088-1098, 2024 | | 2024 |
Single stranded dna enzyme inhibitors FMY Barzak, VV Filichev, E Harjes, S Harjes, GB Jameson, HM Kurup, ... US Patent App. 18/262,896, 2024 | | 2024 |
Abstract 1224 Interaction of the cancer DNA cytosine deaminase APOBEC3B with nucleic acid structures M Carpenter, S Harjes, G Jameson, V Filichev, E Harjes, R Harris Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Synthesis of 1, 4-azaphosphinine pyrimidine nucleosides and their evaluation as inhibitors of human cytidine deaminase and APOBEC3A MV Kvach, S Harjes, HM Kurup, GB Jameson, E Harjes, VV Filichev Beilstein Archives 2024 (1), 9, 2024 | | 2024 |
Publication Date 08 Feb. 2024 MV Kvach, S Harjes, HM Kurup, EH Jameson, VV Filichev | | 2024 |