Siroheme-and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis is a sulfite reductase with a covalent Cys-Tyr bond in the active site R Schnell, T Sandalova, U Hellman, Y Lindqvist, G Schneider Journal of Biological Chemistry 280 (29), 27319-27328, 2005 | 136 | 2005 |
Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis: crystal structures of the enzyme α-aminoacrylate intermediate … R Schnell, W Oehlmann, M Singh, G Schneider Journal of Biological Chemistry 282 (32), 23473-23481, 2007 | 110 | 2007 |
A secretagogin locus of the mammalian hypothalamus controls stress hormone release RA Romanov, A Alpár, MD Zhang, A Zeisel, A Calas, M Landry, ... The EMBO journal 34 (1), 36-54, 2015 | 83 | 2015 |
Peptidoglycan remodeling in Mycobacterium tuberculosis: comparison of structures and catalytic activities of RipA and RipB D Böth, G Schneider, R Schnell Journal of molecular biology 413 (1), 247-260, 2011 | 76 | 2011 |
Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria D Agren, R Schnell, W Oehlmann, M Singh, G Schneider Journal of Biological Chemistry 283 (46), 31567-31574, 2008 | 76 | 2008 |
Directional cloning of native PCR products with preformed sticky ends (autosticky PCR) J Gal, R Schnell, S Szekeres, M Kalman Molecular and General Genetics MGG 260 (6), 569-573, 1999 | 73 | 1999 |
The metDd-Methionine Transporter Locus of Escherichia coli Is an ABC Transporter Gene Cluster J Gál, A Szvetnik, R Schnell, M Kálmán Journal of bacteriology 184 (17), 4930-4932, 2002 | 72 | 2002 |
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis K Brunner, S Maric, RS Reshma, H Almqvist, B Seashore-Ludlow, ... Journal of Medicinal Chemistry 59 (14), 6848-6859, 2016 | 63 | 2016 |
Structure-Guided Design of Novel Thiazolidine Inhibitors of O-Acetyl Serine Sulfhydrylase from Mycobacterium tuberculosis O Poyraz, VU Jeankumar, S Saxena, R Schnell, M Haraldsson, ... Journal of medicinal chemistry 56 (16), 6457-6466, 2013 | 62 | 2013 |
A TRPV 1‐to‐secretagogin regulatory axis controls pancreatic β‐cell survival by modulating protein turnover K Malenczyk, F Girach, E Szodorai, P Storm, Å Segerstolpe, G Tortoriello, ... The EMBO journal 36 (14), 2107-2125, 2017 | 60 | 2017 |
Structure of LdtMt2, an L, D-transpeptidase from Mycobacterium tuberculosis D Böth, EM Steiner, D Stadler, Y Lindqvist, R Schnell, G Schneider Acta Crystallographica Section D: Biological Crystallography 69 (3), 432-441, 2013 | 54 | 2013 |
The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery L Moynie, R Schnell, SA McMahon, T Sandalova, WA Boulkerou, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 47 | 2013 |
Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis Y Lindqvist, H Koskiniemi, A Jansson, T Sandalova, R Schnell, Z Liu, ... Journal of molecular biology 393 (4), 966-977, 2009 | 47 | 2009 |
Binding and processing of β‐lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis EM Steiner, G Schneider, R Schnell The FEBS Journal 284 (5), 725-741, 2017 | 44 | 2017 |
Discovery of novel inhibitors targeting the Mycobacterium tuberculosis O-acetylserine sulfhydrylase (CysK1) using virtual high-throughput screening Ö Poyraz, S Saxena, R Schnell, P Yogeeswari, G Schneider, D Sriram Bioorganic & medicinal chemistry letters 23 (5), 1182-1186, 2013 | 44 | 2013 |
Pyridoxal-phosphate dependent mycobacterial cysteine synthases: Structure, mechanism and potential as drug targets R Schnell, D Sriram, G Schneider Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (9), 1175-1183, 2015 | 41 | 2015 |
1.9 Å structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis R Schnell, D Ågren, G Schneider Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 41 | 2008 |
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens MJ Fogg, P Alzari, M Bahar, I Bertini, JM Betton, WP Burmeister, ... Acta Crystallographica Section D: Biological Crystallography 62 (10), 1196-1207, 2006 | 41 | 2006 |
Structural and functional characterization of the BcsG subunit of the cellulose synthase in Salmonella typhimurium L Sun, P Vella, R Schnell, A Polyakova, G Bourenkov, F Li, A Cimdins, ... Journal of molecular biology 430 (18), 3170-3189, 2018 | 40 | 2018 |
Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa CD Cukier, AG Hope, AA Elamin, L Moynie, R Schnell, S Schach, ... ACS chemical biology 8 (11), 2518-2527, 2013 | 40 | 2013 |