关注
Gemma Migneco
Gemma Migneco
Scientific Director
在 jefferson.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
A Samson, KJ Scott, D Taggart, EJ West, E Wilson, GJ Nuovo, S Thomson, ...
Science translational medicine 10 (422), eaam7577, 2018
3722018
The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism
S Pavlides, A Tsirigos, G Migneco, D Whitaker-Menezes, B Chiavarina, ...
Cell cycle 9 (17), 3485-3505, 2010
2842010
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors
UE Martinez-Outschoorn, S Pavlides, D Whitaker-Menezes, KM Daumer, ...
Cell Cycle 9 (12), 2423-2433, 2010
2702010
HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells: autophagy drives compartment-specific oncogenesis
B Chiavarina, D Whitaker-Menezes, G Migneco, UE Martinez-Outschoorn, ...
Cell cycle 9 (17), 3534-3551, 2010
2662010
The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts
G Bonuccelli, D Whitaker-Menezes, R Castello-Cros, S Pavlides, ...
Cell cycle 9 (10), 1960-1971, 2010
2582010
The autophagic tumor stroma model of cancer or “battery-operated tumor growth” a simple solution to the autophagy paradox
UE Martinez-Outschoorn, D Whitaker-Menezes, S Pavlides, B Chiavarina, ...
Cell cycle 9 (21), 4297-4306, 2010
1892010
Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling
G Migneco, D Whitaker-Menezes, B Chiavarina, R Castello-Cros, ...
Cell cycle 9 (12), 2412-2422, 2010
1672010
Potentiating oncolytic virus-induced immune-mediated tumor cell killing using histone deacetylase inhibition
VA Jennings, GB Scott, AMS Rose, KJ Scott, G Migneco, B Keller, K Reilly, ...
Molecular Therapy 27 (6), 1139-1152, 2019
532019
Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia
C Parrish, GB Scott, G Migneco, KJ Scott, LP Steele, E Ilett, EJ West, ...
Leukemia 29 (9), 1799-1810, 2015
502015
Targeting human plasmacytoid dendritic cells through BDCA2 prevents skin inflammation and fibrosis in a novel xenotransplant mouse model of scleroderma
RL Ross, C Corinaldesi, G Migneco, IM Carr, A Antanaviciute, ...
Annals of the Rheumatic Diseases 80 (7), 920-929, 2021
322021
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy
ME Wedge, VA Jennings, MJF Crupi, J Poutou, T Jamieson, A Pelin, ...
Nature communications 13 (1), 1898, 2022
282022
Silencing of caveolin-1 in fibroblasts as opposed to epithelial tumor cells results in increased tumor growth rate and chemoresistance in a human pancreatic cancer model
K Kamposioras, C Tsimplouli, C Verbeke, A Anthoney, A Daoukopoulou, ...
International journal of oncology 54 (2), 537-549, 2019
202019
Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche
LME Müller, G Migneco, GB Scott, J Down, S King, B Askar, V Jennings, ...
Journal for immunotherapy of cancer 9 (3), 2021
142021
SAT0281 BIOSAMPLES FROM AT RISK SSC PATIENTS SHOW CLASSIC PATHOLOGICAL SIGNS OF SCLERODERMA: OPPORTUNITY FOR DIAGNOSIS OF PRE-CLINICAL SSC
R Ross, I Georgiou, A Carriero, G Abignano, C Wasson, G Migneco, ...
Annals of the Rheumatic Diseases 79 (Suppl 1), 1085-1085, 2020
12020
Evaluating the contribution of anti-myeloma immunity for the efficacy of oncolytic reovirus therapy
LME Müller, C Parrish, G Migneco, GB Scott, M Holmes, AA Melcher, ...
Clinical Cancer Research 23 (24_Supplement), 18-18, 2017
12017
The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis
CW Wasson, E De Lorenzis, EM Clavane, RL Ross, KA Walker, ...
Journal of Investigative Dermatology, 2024
2024
Enhancing oncolytic virotherapy by exosome-mediated microRNA reprograming of the tumour microenvironment.
V Jennings, R Rumbold-Hall, G Migneco, T Barr, K Reilly, N Ingram, ...
bioRxiv, 2024.06. 07.597913, 2024
2024
OP0113 The Beta Secretase Bace1 Drives Systemic Sclerosis Fibroblasts Activation Through Β-Catenin And Notch Signalling
C Wasson, E Clavane, R Ross, G Migneco, C Antinozzi, J Brown, ...
Annals of the Rheumatic Diseases 82 (Suppl 1), 75-75, 2023
2023
The Beta secretase BACE1 drives Systemic Sclerosis fibroblasts activation through β-catenin and Notch signalling
CW Wasson, EM Clavane, RL Ross, G Migneco, C Antinozzi, JMY Brown, ...
bioRxiv, 2022.12. 22.521579, 2022
2022
P163 Biosamples from at risk SSc patients show classic pathological signs of scleroderma: opportunity for a diagnosis of pre-clinical SSc
RL Ross, I Georgiou, A Carriero, G Abignano, C Wasson, G Migneco, ...
Rheumatology 59 (Supplement_2), keaa111. 158, 2020
2020
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