| Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ... science 303 (5666), 2011-2015, 2004 | 3814 | 2004 |
| Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 R Mostoslavsky, KF Chua, DB Lombard, WW Pang, MR Fischer, L Gellon, ... Cell 124 (2), 315-329, 2006 | 1875 | 2006 |
| Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice HL Cheng, R Mostoslavsky, S Saito, JP Manis, Y Gu, P Patel, R Bronson, ... Proceedings of the National Academy of Sciences 100 (19), 10794-10799, 2003 | 1335 | 2003 |
| SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin E Michishita, RA McCord, E Berber, M Kioi, H Padilla-Nash, M Damian, ... Nature 452 (7186), 492-496, 2008 | 1271 | 2008 |
| SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span TLA Kawahara, E Michishita, AS Adler, M Damian, E Berber, M Lin, ... Cell 136 (1), 62-74, 2009 | 1242 | 2009 |
| ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression X Shi, T Hong, KL Walter, M Ewalt, E Michishita, T Hung, D Carney, ... Nature 442 (7098), 96-99, 2006 | 1157 | 2006 |
| DNA repair, genome stability, and aging DB Lombard, KF Chua, R Mostoslavsky, S Franco, M Gostissa, FW Alt Cell 120 (4), 497-512, 2005 | 1098 | 2005 |
| Transcription-targeted DNA deamination by the AID antibody diversification enzyme J Chaudhuri, M Tian, C Khuong, K Chua, E Pinaud, FW Alt Nature 422 (6933), 726-730, 2003 | 899 | 2003 |
| Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX CH Bassing, KF Chua, JA Sekiguchi, H Suh, SR Whitlow, JC Fleming, ... Proceedings of the National Academy of Sciences 99 (12), 8173-8178, 2002 | 673 | 2002 |
| Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally Y Zhang, SH Kwon, T Yamaguchi, F Cubizolles, S Rousseaux, M Kneissel, ... Molecular and cellular biology 28 (5), 1688-1701, 2008 | 664 | 2008 |
| SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation MF Barber, E Michishita-Kioi, Y Xi, L Tasselli, M Kioi, Z Moqtaderi, ... Nature 487 (7405), 114-118, 2012 | 651 | 2012 |
| Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors CH Bassing, H Suh, DO Ferguson, KF Chua, J Manis, M Eckersdorff, ... Cell 114 (3), 359-370, 2003 | 614 | 2003 |
| The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC JA Berglund, K Chua, N Abovich, R Reed, M Rosbash Cell 89 (5), 781-787, 1997 | 450 | 1997 |
| Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6 E Michishita, RA McCord, LD Boxer, MF Barber, T Hong, O Gozani, ... Cell cycle 8 (16), 2664-2666, 2009 | 434 | 2009 |
| SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair RA McCord, E Michishita, T Hong, E Berber, LD Boxer, R Kusumoto, ... Aging (Albany NY) 1 (1), 109, 2009 | 380 | 2009 |
| Nuclear DNA damage signalling to mitochondria in ageing EF Fang, M Scheibye-Knudsen, KF Chua, MP Mattson, DL Croteau, ... Nature reviews Molecular cell biology 17 (5), 308-321, 2016 | 376 | 2016 |
| Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress KF Chua, R Mostoslavsky, DB Lombard, WW Pang, S Saito, S Franco, ... Cell metabolism 2 (1), 67-76, 2005 | 312 | 2005 |
| Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ... Nature immunology 12 (1), 29, 2011 | 292 | 2011 |
| SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease J Shin, M He, Y Liu, S Paredes, L Villanova, K Brown, X Qiu, N Nabavi, ... Cell reports 5 (3), 654-665, 2013 | 286 | 2013 |
| SIRT6: novel mechanisms and links to aging and disease L Tasselli, W Zheng, KF Chua Trends in Endocrinology & Metabolism 28 (3), 168-185, 2017 | 258 | 2017 |
