Twist1-induced invadopodia formation promotes tumor metastasis MA Eckert, TM Lwin, AT Chang, J Kim, E Danis, L Ohno-Machado, J Yang Cancer cell 19 (3), 372-386, 2011 | 551 | 2011 |
Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model T Murakami, S Li, Q Han, Y Tan, T Kiyuna, K Igarashi, K Kawaguchi, ... Oncotarget 8 (22), 35630, 2017 | 84 | 2017 |
Tumor-specific labeling of pancreatic cancer using a humanized anti-CEA antibody conjugated to a near-infrared fluorophore TM Lwin, T Murakami, K Miyake, PJ Yazaki, JE Shivley, RM Hoffman, ... Annals of surgical oncology 25, 1079-1085, 2018 | 51 | 2018 |
Indocyanine green fluorescence-guided parathyroidectomy for primary hyperparathyroidism JC DeLong, EP Ward, TM Lwin, KT Brumund, KJ Kelly, S Horgan, ... Surgery 163 (2), 388-392, 2018 | 50 | 2018 |
ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions MA Eckert, M Santiago-Medina, TM Lwin, J Kim, SA Courtneidge, J Yang Journal of cell science 130 (12), 2036-2048, 2017 | 47 | 2017 |
MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX) K Kawaguchi, K Igarashi, T Murakami, T Kiyuna, TM Lwin, HK Hwang, ... Oncotarget 8 (29), 47490, 2017 | 46 | 2017 |
Effective fluorescence‐guided surgery of liver metastasis using a fluorescent anti‐CEA antibody Y Hiroshima, TM Lwin, T Murakami, AA Mawy, T Kuniya, T Chishima, ... Journal of surgical oncology 114 (8), 951-958, 2016 | 42 | 2016 |
The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago T Murakami, T Kiyuna, K Kawaguchi, K Igarashi, AS Singh, Y Hiroshima, ... Cell Cycle 16 (11), 1046-1052, 2017 | 41 | 2017 |
Oral recombinant methioninase overcomes colorectal-cancer liver metastasis resistance to the combination of 5-fluorouracil and oxaliplatinum in a patient-derived orthotopic … H Oshiro, Y Tome, T Kiyuna, SN Yoon, TM Lwin, Q Han, Y Tan, K Miyake, ... Anticancer research 39 (9), 4667-4671, 2019 | 40 | 2019 |
Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic … K Kawaguchi, K Miyake, Q Han, S Li, Y Tan, K Igarashi, TM Lwin, ... Cell Cycle 17 (7), 868-873, 2018 | 39 | 2018 |
Advantages of patient‐derived orthotopic mouse models and genetic reporters for developing fluorescence‐guided surgery TM Lwin, RM Hoffman, M Bouvet Journal of surgical oncology 118 (2), 253-264, 2018 | 35 | 2018 |
Tumor-specific near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer TM Lwin, S Hernot, H Hollandsworth, S Amirfakhri, F Filemoni, P Debie, ... Surgery 168 (1), 85-91, 2020 | 33 | 2020 |
Cervical cancer patient-derived orthotopic xenograft (PDOX) is sensitive to cisplatinum and resistant to nab-paclitaxel T Murakami, T Murata, K Kawaguchi, T Kiyuna, K Igarashi, HK Hwang, ... Anticancer research 37 (1), 61-65, 2017 | 28 | 2017 |
The development of fluorescence guided surgery for pancreatic cancer: from bench to clinic TM Lwin, RM Hoffman, M Bouvet Expert review of anticancer therapy 18 (7), 651-662, 2018 | 27 | 2018 |
MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model K Kawaguchi, K Igarashi, K Miyake, TM Lwin, M Miyake, T Kiyuna, ... Tissue and Cell 52, 124-128, 2018 | 27 | 2018 |
Improved antibody-guided surgery with a near-infrared dye on a pegylated linker for CEA-positive tumors PJ Yazaki, TM Lwin, M Minnix, L Li, A Sherman, J Molnar, A Miller, ... Journal of Biomedical Optics 24 (6), 066012-066012, 2019 | 25 | 2019 |
The mucin family of proteins: candidates as potential biomarkers for colon cancer KE Cox, S Liu, TM Lwin, RM Hoffman, SK Batra, M Bouvet Cancers 15 (5), 1491, 2023 | 23 | 2023 |
Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model TM Lwin, K Miyake, T Murakami, JC DeLong, PJ Yazaki, JE Shivley, ... Molecular-Guided Surgery: Molecules, Devices, and Applications IV 10478, 30-39, 2018 | 23 | 2018 |
Anti-claudin-1 conjugated to a near-infrared fluorophore targets colon cancer in pdox mouse models HM Hollandsworth, TM Lwin, S Amirfakhri, F Filemoni, SK Batra, ... Journal of Surgical Research 242, 145-150, 2019 | 19 | 2019 |
Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients R Pal, TM Lwin, M Krishnamoorthy, HR Collins, CD Chan, A Prilutskiy, ... Nature Biomedical Engineering, 1-18, 2023 | 17 | 2023 |