Metabolomics: from fundamentals to clinical applications AJ Chetwynd, WB Dunn, G Rodriguez-Blanco Adv. Exp. Med. Biol 965, 19-44, 2017 | 168* | 2017 |
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ... Nature genetics 53 (1), 16-26, 2021 | 160 | 2021 |
Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis P Sadiku, JA Willson, EM Ryan, D Sammut, P Coelho, ER Watts, ... Cell metabolism 33 (2), 411-423. e4, 2021 | 141 | 2021 |
2, 4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer A Blomme, CA Ford, E Mui, R Patel, C Ntala, LE Jamieson, M Planque, ... Nature Communications 11 (1), 2508, 2020 | 137 | 2020 |
Targeting the metabolic response to statin-mediated oxidative stress produces a synergistic antitumor response GH McGregor, AD Campbell, SK Fey, S Tumanov, D Sumpton, GR Blanco, ... Cancer research 80 (2), 175-188, 2020 | 100 | 2020 |
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition A Roca-Portoles, G Rodriguez-Blanco, D Sumpton, C Cloix, M Mullin, ... Cell death & disease 11 (8), 616, 2020 | 75 | 2020 |
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism DG Ryan, M Yang, HA Prag, GR Blanco, E Nikitopoulou, ... Elife 10, e72593, 2021 | 71 | 2021 |
msPurity: automated evaluation of precursor ion purity for mass spectrometry-based fragmentation in metabolomics TN Lawson, RJM Weber, MR Jones, AJ Chetwynd, G Rodrı́guez-Blanco, ... Analytical chemistry 89 (4), 2432-2439, 2017 | 55 | 2017 |
Proteomics identifies a type I IFN, prothrombotic hyperinflammatory circulating COVID-19 neutrophil signature distinct from non-COVID-19 ARDS MedRxiv, 2020 | 49* | 2020 |
Formate induces a metabolic switch in nucleotide and energy metabolism K Oizel, J Tait-Mulder, J Fernandez-de-Cossio-Diaz, M Pietzke, H Brunton, ... Cell death & disease 11 (5), 310, 2020 | 47 | 2020 |
Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells AJD Marcus J. Lyall, Jessy Cartier, John P. Thomson, Kate Cameron, Jose ... Philosophical Transactions of the Royal Society B, 2018 | 41 | 2018 |
Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer A Almanza, K Mnich, A Blomme, CM Robinson, G Rodriguez-Blanco, ... Nature communications 13 (1), 2493, 2022 | 40 | 2022 |
Nicotinamide nucleotide transhydrogenase as a novel treatment target in adrenocortical carcinoma V Chortis, AE Taylor, CL Doig, MD Walsh, E Meimaridou, C Jenkinson, ... Endocrinology 159 (8), 2836-2849, 2018 | 32 | 2018 |
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism ER Watts, AJM Howden, T Morrison, P Sadiku, J Hukelmann, ... The Journal of Clinical Investigation 131 (10), 2021 | 27 | 2021 |
Bidirectional Cross-Talk between Biliary Epithelium and Th17 Cells Promotes Local Th17 Expansion and Bile Duct Proliferation in Biliary Liver Diseases DHAYHO Hannah C. Jeffery, Stuart Hunter, Elizabeth H. Humphreys, Ricky ... The Journal of immunology, 2019 | 27 | 2019 |
Serum levels of arachidonic acid metabolites change during prostate cancer progression G Rodríguez‐Blanco, PC Burgers, LJM Dekker, JJN IJzermans, ... The Prostate 74 (6), 618-627, 2014 | 27 | 2014 |
Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice J Eckrich, K Frenis, G Rodriguez-Blanco, Y Ruan, S Jiang, MTB Jimenez, ... Redox biology 46, 102063, 2021 | 26 | 2021 |
NRF2 activation reprograms defects in oxidative metabolism to restore macrophage function in chronic obstructive pulmonary disease EM Ryan, P Sadiku, P Coelho, ER Watts, A Zhang, AJM Howden, ... American journal of respiratory and critical care medicine 207 (8), 998-1011, 2023 | 25 | 2023 |
SLFN5 regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer RS Martinez, MJ Salji, L Rushworth, C Ntala, G Rodriguez Blanco, ... Cancer Research 81 (13), 3664-3678, 2021 | 24 | 2021 |
Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium LJVP Xuan Wang-Kan, Giovanny Rodríguez-Blanco, Andrew D. Southam, Catherine ... mBio, 2021 | 24 | 2021 |