6-Alkylamino-and 2, 3-Dihydro-3 ‘-methoxy-2-phenyl-4-quinazolinones and related compounds: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization MJ Hour, LJ Huang, SC Kuo, Y Xia, K Bastow, Y Nakanishi, E Hamel, ... Journal of medicinal chemistry 43 (23), 4479-4487, 2000 | 526 | 2000 |
Antitumor agents. Part 204: synthesis and biological evaluation of substituted 2-aryl quinazolinones Y Xia, ZY Yang, MJ Hour, SC Kuo, P Xia, KF Bastow, Y Nakanishi, ... Bioorganic & medicinal chemistry letters 11 (9), 1193-1196, 2001 | 268 | 2001 |
Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymes HWC Leung, CJ Lin, MJ Hour, WH Yang, MY Wang, HZ Lee Food and Chemical Toxicology 45 (10), 2005-2013, 2007 | 184 | 2007 |
Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents TC Ko, MJ Hour, JC Lien, CM Teng, KH Lee, SC Kuo, LJ Huang Bioorganic & medicinal chemistry letters 11 (3), 279-282, 2001 | 138 | 2001 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells JS Yang, MJ Hour, WW Huang, KL Lin, SC Kuo, JG Chung Journal of Pharmacology and Experimental Therapeutics 334 (2), 477-488, 2010 | 96 | 2010 |
Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway SF Peng, CY Lee, MJ Hour, SC Tsai, DH Kuo, FA Chen, PC Shieh, ... International journal of oncology 44 (1), 238-246, 2014 | 71 | 2014 |
Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice CC Lu, JS Yang, JH Chiang, MJ Hour, KL Lin, JJ Lin, WW Huang, ... PloS one 7 (5), e36831, 2012 | 69 | 2012 |
5-Lipoxygenase inhibitors attenuate TNF-α-induced inflammation in human synovial fibroblasts HC Lin, TH Lin, MY Wu, YC Chiu, CH Tang, MJ Hour, HC Liou, HJ Tu, ... PLoS One 9 (9), e107890, 2014 | 65 | 2014 |
Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis HZ Lee, WH Yang, MJ Hour, CY Wu, WH Peng, BY Bao, PH Han, DT Bau European journal of pharmacology 648 (1-3), 50-58, 2010 | 62 | 2010 |
Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A … MJ Hour, SH Huang, CY Chang, YK Lin, CY Wang, YS Chang, CW Lin Evidence‐Based Complementary and Alternative Medicine 2013 (1), 750803, 2013 | 58 | 2013 |
Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor … JH Chiang, JS Yang, CC Lu, MJ Hour, SJ Chang, TH Lee, JG Chung Toxicology and applied pharmacology 269 (2), 150-162, 2013 | 51 | 2013 |
Protection of dopaminergic neurons by 5-lipoxygenase inhibitor KH Kang, HH Liou, MJ Hour, HC Liou, WM Fu Neuropharmacology 73, 380-387, 2013 | 48 | 2013 |
Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells MJ Hour, SC Tsai, HC Wu, MW Lin, JG Chung, JB Wu, JH Chiang, ... International journal of oncology 41 (4), 1513-1519, 2012 | 47 | 2012 |
Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38 JS Yang, MJ Hour, SC Kuo, LJ Huang, MR Lee Anticancer research 24 (3A), 1769-1778, 2004 | 46 | 2004 |
P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells HWC Leung, MJ Hour, WT Chang, YC Wu, MY Lai, MY Wang, HZ Lee Food and chemical toxicology 46 (11), 3389-3400, 2008 | 45 | 2008 |
Tubacin, an HDAC6 selective inhibitor, reduces the replication of the Japanese encephalitis virus via the decrease of viral RNA synthesis CY Lu, YC Chang, CH Hua, C Chuang, SH Huang, SH Kung, MJ Hour, ... International Journal of Molecular Sciences 18 (5), 954, 2017 | 44 | 2017 |
Synthesis and Antiplatelet Activities of N-Arylmethyl-3, 4-dimethylpyrano [2, 3-c] pyrazol-6-one Derivatives LJ HUANG, MJ HOUR, CM TENG, SC KUO Chemical and pharmaceutical bulletin 40 (9), 2547-2551, 1992 | 44 | 1992 |
Cell death caused by quinazolinone HMJ-38 challenge in oral carcinoma CAL 27 cells: Dissections of endoplasmic reticulum stress, mitochondrial dysfunction and tumor xenografts CC Lu, JS Yang, JH Chiang, MJ Hour, KL Lin, TH Lee, JG Chung Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (7), 2310-2320, 2014 | 43 | 2014 |
Inhibition of invasion and migration by newly synthesized quinazolinone MJ-29 in human oral cancer CAL 27 cells through suppression of MMP-2/9 expression and combined down … CC Lu, JS Yang, JH Chiang, MJ Hour, S Amagaya, KW Lu, JP Lin, ... Anticancer research 32 (7), 2895-2903, 2012 | 41 | 2012 |
SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling CY Wang, CY Lu, SW Li, CC Lai, CH Hua, SH Huang, YJ Lin, MJ Hour, ... Virus Research 235, 58-66, 2017 | 39 | 2017 |