Melatonin prevents neuroinflammation and relieves depression by attenuating autophagy impairment through FOXO3a regulation T Ali, SU Rahman, Q Hao, W Li, Z Liu, F Ali Shah, I Murtaza, Z Zhang, ... Journal of pineal research 69 (2), e12667, 2020 | 226 | 2020 |
Quercetin exerts a neuroprotective effect through inhibition of the iNOS/NO system and pro-inflammation gene expression in PC12 cells and in zebrafish ZJ Zhang, LCV Cheang, MW Wang, SMY Lee International journal of molecular medicine 27 (2), 195-203, 2011 | 193 | 2011 |
Baicalein protects against 6-OHDA-induced neurotoxicity through activation of Keap1/Nrf2/HO-1 and involving PKCα and PI3K/AKT signaling pathways Z Zhang, W Cui, G Li, S Yuan, D Xu, MPM Hoi, Z Lin, J Dou, Y Han, ... Journal of Agricultural and Food Chemistry 60 (33), 8171-8182, 2012 | 181 | 2012 |
Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment Z Zhang, J Jiang, P Yu, X Zeng, JW Larrick, Y Wang Journal of translational medicine 7, 1-13, 2009 | 166 | 2009 |
Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease Z Zhang, G Li, SSW Szeto, CM Chong, Q Quan, C Huang, W Cui, B Guo, ... Free Radical Biology and Medicine 84, 331-343, 2015 | 158 | 2015 |
Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC JY Tang, S Li, ZH Li, ZJ Zhang, G Hu, LCV Cheang, D Alex, MPM Hoi, ... PloS one 5 (7), e11822, 2010 | 141 | 2010 |
Synthesis and evaluation of antibacterial activities of andrographolide analogues X Jiang, P Yu, J Jiang, Z Zhang, Z Wang, Z Yang, Z Tian, SC Wright, ... European journal of medicinal chemistry 44 (7), 2936-2943, 2009 | 133 | 2009 |
Ethanolic Extract of Fructus Alpinia oxyphylla Protects Against 6-Hydroxydopamine-Induced Damage of PC12 Cells In Vitro and Dopaminergic Neurons in Zebrafish ZJ Zhang, LCV Cheang, MW Wang, GH Li, IK Chu, ZX Lin, SMY Lee Cellular and molecular neurobiology 32, 27-40, 2012 | 111 | 2012 |
Antioxidative and thrombolytic TMP nitrone for treatment of ischemic stroke Y Sun, J Jiang, Z Zhang, P Yu, L Wang, C Xu, W Liu, Y Wang Bioorganic & medicinal chemistry 16 (19), 8868-8874, 2008 | 106 | 2008 |
Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer’s disease C Chen, C Yang, J Wang, X Huang, H Yu, S Li, S Li, Z Zhang, J Liu, ... Journal of Pineal Research 71 (4), e12774, 2021 | 98 | 2021 |
A novel Danshensu derivative confers cardioprotection via PI3K/Akt and Nrf2 pathways G Cui, L Shan, M Hung, S Lei, I Choi, Z Zhang, P Yu, P Hoi, Y Wang, ... International Journal of Cardiology 168 (2), 1349-1359, 2013 | 88 | 2013 |
Tetramethylpyrazine nitrone activates the BDNF/Akt/CREB pathway to promote post‐ischaemic neuroregeneration and recovery of neurological functions in rats G Zhang, T Zhang, N Li, L Wu, J Gu, C Li, C Zhao, W Liu, L Shan, P Yu, ... British Journal of Pharmacology 175 (3), 517-531, 2018 | 81 | 2018 |
Synthesis and preliminary antitumor activity evaluation of a DHA and doxorubicin conjugate Y Wang, L Li, W Jiang, Z Yang, Z Zhang Bioorganic & medicinal chemistry letters 16 (11), 2974-2977, 2006 | 78 | 2006 |
Neuroprotective and axonal outgrowth-promoting effects of tetramethylpyrazine nitrone in chronic cerebral hypoperfusion rats and primary hippocampal neurons exposed to hypoxia T Zhang, J Gu, L Wu, N Li, Y Sun, P Yu, Y Wang, G Zhang, Z Zhang Neuropharmacology 118, 137-147, 2017 | 67 | 2017 |
Resveratrol derivative, trans‐3, 5, 4′‐trimethoxystilbene, exerts antiangiogenic and vascular‐disrupting effects in zebrafish through the downregulation of VEGFR2 and cell … D Alex, EC Leong, ZJ Zhang, GTH Yan, SH Cheng, CW Leong, ZH Li, ... Journal of cellular biochemistry 109 (2), 339-346, 2010 | 66 | 2010 |
Andrographolide derivative AL-1 ameliorates TNBS-induced colitis in mice: involvement of NF-кB and PPAR-γ signaling pathways Y Yang, H Yan, M Jing, Z Zhang, G Zhang, Y Sun, L Shan, P Yu, Y Wang, ... Scientific Reports 6 (1), 29716, 2016 | 65 | 2016 |
From omics to drug metabolism and high content screen of natural product in zebrafish: a new model for discovery of neuroactive compound MW Hung, ZJ Zhang, S Li, B Lei, S Yuan, GZ Cui, P Man Hoi, K Chan, ... Evidence‐Based Complementary and Alternative Medicine 2012 (1), 605303, 2012 | 65 | 2012 |
The anti‐cancer agent SU4312 unexpectedly protects against MPP+‐induced neurotoxicity via selective and direct inhibition of neuronal NOS W Cui, Z Zhang, W Li, S Hu, S Mak, H Zhang, R Han, S Yuan, S Li, F Sa, ... British Journal of Pharmacology 168 (5), 1201-1214, 2013 | 63 | 2013 |
Ginsenoside Rg1 ameliorates behavioral abnormalities and modulates the hippocampal proteomic change in triple transgenic mice of Alzheimer’s disease L Nie, J Xia, H Li, Z Zhang, Y Yang, X Huang, Z He, J Liu, X Yang Oxidative medicine and cellular longevity 2017 (1), 6473506, 2017 | 59 | 2017 |
Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson’s disease in vitro and in vivo B Guo, D Xu, H Duan, J Du, Z Zhang, SMY Lee, Y Wang Biological and Pharmaceutical Bulletin 37 (2), 274-285, 2014 | 57 | 2014 |