A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation DA Gutierrez, RE DeJesus, L Contreras, IA Rodriguez-Palomares, ... Cell biology and toxicology 35, 503-519, 2019 | 48 | 2019 |
Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis PJ Villanueva, A Martinez, ST Baca, RE DeJesus, M Larragoity, ... PLoS One 13 (11), e0206467, 2018 | 37 | 2018 |
Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones L Contreras, RI Calderon, A Varela-Ramirez, HY Zhang, Y Quan, U Das, ... Cellular Oncology 41, 623-636, 2018 | 30 | 2018 |
The antimalarial drug pyronaridine inhibits topoisomerase II in breast cancer cells and hinders tumor progression in vivo PJ Villanueva, DA Gutierrez, L Contreras, K Parra, A Segura-Cabrera, ... Clinical cancer drugs 8 (1), 50, 2021 | 11 | 2021 |
Identification of a potent cytotoxic pyrazole with anti-breast cancer activity that alters multiple pathways DA Gutierrez, L Contreras, PJ Villanueva, EA Borrego, ... Cells 11 (2), 254, 2022 | 9 | 2022 |
El Impacto de las Tecnologías De Información y Comunicación (TIC) en el Proceso de Enseñanza Aprendizaje M Gómez, L Contreras, D Gutiérrez Innovación Educativa 16 (71), 61-80, 2016 | 8 | 2016 |
Identification of a unique cytotoxic thieno [2, 3-c] pyrazole derivative with potent and selective anticancer effects in vitro JD Hess, LH Macias, DA Gutierrez, K Moran-Santibanez, L Contreras, ... Biology 11 (6), 930, 2022 | 6 | 2022 |
Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms L Contreras, S Medina, AY Schiaffino Bustamante, EA Borrego, ... Pharmacological Reports 74 (1), 159-174, 2022 | 6 | 2022 |
Design, synthesis and tumour-selective toxicity of novel 1-[3-{3, 5-Bis (benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone oximes and related quaternary ammonium salts PK Roayapalley, JR Dimmock, L Contreras, KS Balderrama, RJ Aguilera, ... Molecules 26 (23), 7132, 2021 | 5 | 2021 |
Rapid shift from SARS-CoV-2 delta to Omicron sub-variants within a dynamic Southern US Borderplex E Robles-Escajeda, JE Mohl, L Contreras, AP Betancourt, BM Mancera, ... Viruses 15 (3), 658, 2023 | 4 | 2023 |
Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines RM Swain, L Contreras, A Varela-Ramirez, M Hossain, U Das, ... Investigational new drugs 40 (5), 905-921, 2022 | 3 | 2022 |
UBTF Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis J Barajas, M Umeda, J Ma, M Khanlari, MP Walsh, T Westover, ... Blood 142, 838, 2023 | | 2023 |
In Vitro Investigation of Tumor Selective Piperidones as Therapeutic Agents Against Leukemia Cancer Cells L Contreras The University of Texas at El Paso, 2021 | | 2021 |
UBTF tandem duplications in pediatric myelodysplastic syndrome and acute myeloid leukemia: implications for clinical screening and diagnosis JM Barajas, M Umeda, L Contreras, M Khanlari, T Westover, MP Walsh, ... Haematologica, 2020 | | 2020 |
Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cell lines by two potent piperidones L Contreras, RI Calderon, A Varela, H Zhang, U Das, JR Dimmock, ... MOLECULAR BIOLOGY OF THE CELL 29 (26), 252-252, 2018 | | 2018 |