Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitus CE Tabit, SM Shenouda, M Holbrook, JL Fetterman, S Kiani, AA Frame, ... Circulation 127 (1), 86-95, 2013 | 197 | 2013 |
MEF2A regulates the Gtl2-Dio3 microRNA mega-cluster to modulate WNT signaling in skeletal muscle regeneration CM Snyder, AL Rice, NL Estrella, A Held, SC Kandarian, FJ Naya Development 140 (1), 31-42, 2013 | 153 | 2013 |
A reference human induced pluripotent stem cell line for large-scale collaborative studies CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendraat, L Peng, ... Cell stem cell 29 (12), 1685-1702. e22, 2022 | 123 | 2022 |
Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions JD Pereira, DM DuBreuil, AC Devlin, A Held, Y Sapir, E Berezovski, ... Nature Communications 12 (1), 4744, 2021 | 105 | 2021 |
Human SOD1 ALS Mutations in a Drosophila Knock-In Model Cause Severe Phenotypes and Reveal Dosage-Sensitive Gain- and Loss-of-Function Components A Şahin, A Held, K Bredvik, P Major, TM Achilli, AG Kerson, K Wharton, ... Genetics 205 (2), 707-723, 2017 | 61 | 2017 |
Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration DV Neel, H Basu, G Gunner, MD Bergstresser, RM Giadone, H Chung, ... Neuron 111 (8), 1222-1240. e9, 2023 | 48 | 2023 |
Circuit dysfunction in SOD1-ALS model first detected in sensory feedback prior to motor neuron degeneration is alleviated by BMP signaling A Held, P Major, A Sahin, RA Reenan, D Lipscombe, KA Wharton Journal of Neuroscience 39 (12), 2347-2364, 2019 | 41 | 2019 |
Meta-analysis of genetic modifiers reveals candidate dysregulated pathways in amyotrophic lateral sclerosis KS Yanagi, Z Wu, J Amaya, N Chapkis, AM Duffy, KH Hajdarovic, A Held, ... Neuroscience 396, A3-A20, 2019 | 18 | 2019 |
Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke W Li, ET Mandeville, V Durán-Laforet, N Fukuda, Z Yu, Y Zheng, A Held, ... Nature communications 13 (1), 7812, 2022 | 16 | 2022 |
iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons A Held, M Adler, C Marques, CJ Reyes, AS Kavuturu, ARAA Quadros, ... Cell reports 42 (9), 2023 | 15 | 2023 |
Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia C Marques, A Held, K Dorfman, J Sung, C Song, AS Kavuturu, C Aguilar, ... Acta neuropathologica 147 (1), 56, 2024 | 12 | 2024 |
SLC22A17 as a Cell Death–Linked Regulator of Tight Junctions in Cerebral Ischemia W Li, J Shi, Z Yu, M Garcia-Gabilondo, A Held, L Huang, W Deng, M Ning, ... Stroke 55 (6), 1650-1659, 2024 | 4 | 2024 |
Protein kinase-C beta activation contributes to impaired endothelial insulin signaling in humans with diabetes mellitus CE Tabit, SM Shenouda, M Holbrook, AA Frame, MA Kluge, MA Duess, ... Journal of the American College of Cardiology 59 (13S), E2133-E2133, 2012 | 3 | 2012 |
Glia-neuron signaling mediated by two different BMP ligands impacts synaptic growth M Bartoletti, T Knight, A Held, LM Rand, KA Wharton bioRxiv, 2021.02. 23.432606, 2021 | 1 | 2021 |
MEF2A regulation of a miRNA mega‐cluster is required for proper skeletal muscle regeneration FJ Naya, CM Snyder, A Held, EP Ewen, OM Kielbasa, SC Kandarian The FASEB Journal 25, 874.1-874.1, 2011 | 1 | 2011 |
iPSC Motor Neurons with Familial ALS Mutations Capture Gene Expression Changes in Postmortem Sporadic ALS Motor Neurons A Held, M Adler, C Marques, AS Kavuturu, ARAA Quadros, ... bioRxiv, 2022.10. 25.513780, 2022 | | 2022 |