A global analysis of the receptor tyrosine kinase-protein phosphatase interactome Z Yao, K Darowski, N St-Denis, V Wong, F Offensperger, A Villedieu, ... Molecular cell 65 (2), 347-360, 2017 | 144 | 2017 |
Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex C Sailer, F Offensperger, A Julier, KM Kammer, R Walker-Gray, MG Gold, ... Nature communications 9 (1), 4441, 2018 | 73 | 2018 |
Formation of the alarmones diadenosine triphosphate and tetraphosphate by ubiquitin-and ubiquitin-like-activating enzymes KH Götz, M Mex, K Stuber, F Offensperger, M Scheffner, A Marx Cell Chemical Biology 26 (11), 1535-1543. e5, 2019 | 23 | 2019 |
Identification of small-molecule activators of the ubiquitin ligase E6AP/UBE3A and angelman syndrome-derived E6AP/UBE3A variants F Offensperger, F Müller, J Jansen, D Hammler, KH Götz, A Marx, ... Cell chemical biology 27 (12), 1510-1520. e6, 2020 | 14 | 2020 |
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling A Ng, F Offensperger, JA Cisneros, NS Scholes, M Malik, L Villanti, ... ACS Chemical Biology 18 (12), 2464-2473, 2023 | 9 | 2023 |
Fluorescently labelled ATP analogues for direct monitoring of ubiquitin activation D Hammler, K Stuber, F Offensperger, M Scheffner, A Zumbusch, A Marx Chemistry–A European Journal 26 (28), 6279-6284, 2020 | 9 | 2020 |
FAT10 and NUB1L cooperate to activate the 26S proteasome F Brockmann, N Catone, C Wünsch, F Offensperger, M Scheffner, ... Life Science Alliance 6 (8), 2023 | 2 | 2023 |
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells F Offensperger, G Tin, M Duran-Frigola, E Hahn, S Dobner, CW Ende, ... Science 384 (6694), eadk5864, 2024 | 1 | 2024 |
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors V Dvorak, A Casiraghi, C Colas, A Koren, T Tomek, F Offensperger, ... Cell Chemical Biology 30 (8), 953-964. e9, 2023 | 1 | 2023 |
Cobalamins function as allosteric activators of an Angelman syndrome‐associated UBE3A/E6AP variant F Müller, J Jansen, F Offensperger, D Eichbichler, F Stengel, M Scheffner ChemBioChem 25 (10), e202400184, 2024 | | 2024 |
Characterization of the ubiquitin ligase E6AP by small molecules F Offensperger | | 2020 |
Novel fluorescently labelled ATP analogues for direct monitoring of ubiquitin activation A Marx, D Hammler, K Stuber, F Offensperger, M Scheffner, A Zumbusch Chemistry–A European Journal, 0 | | |