Aerobic glycolysis promotes tumor immune evasion by hexokinase 2-mediated phosphorylation of IκBα D Guo, Y Tong, X Jiang, Y Meng, H Jiang, L Du, Q Wu, S Li, S Luo, M Li, ... Cell metabolism 34 (9), 1312-1324. e6, 2022 | 133 | 2022 |
METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding W Wang, F Shao, X Yang, J Wang, R Zhu, Y Yang, G Zhao, D Guo, Y Sun, ... Nature communications 12 (1), 3803, 2021 | 104 | 2021 |
SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells Y Tong, D Guo, SH Lin, J Liang, D Yang, C Ma, F Shao, M Li, Q Yu, ... Molecular Cell 81 (11), 2303-2316. e8, 2021 | 96 | 2021 |
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis X Yang, F Shao, D Guo, W Wang, J Wang, R Zhu, Y Gao, J He, Z Lu Cell Death & Disease 12 (5), 462, 2021 | 96 | 2021 |
Cancer metabolism and tumor microenvironment: fostering each other? Y Yuan, H Li, W Pu, L Chen, D Guo, H Jiang, B He, S Qin, K Wang, N Li, ... Science China Life Sciences, 1-44, 2022 | 85 | 2022 |
CDK5 activator protein p25 preferentially binds and activates GSK3β HM Chow, D Guo, JC Zhou, GY Zhang, HF Li, K Herrup, J Zhang Proceedings of the National Academy of Sciences 111 (45), E4887-E4895, 2014 | 72 | 2014 |
KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells Y Tong, D Guo, D Yan, C Ma, F Shao, Y Wang, S Luo, L Lin, J Tao, ... Cancer letters 469, 1-10, 2020 | 60 | 2020 |
CDK5-mediated phosphorylation and stabilization of TPX2 promotes hepatocellular tumorigenesis F Wang, W Zhao, Y Gao, J Zhou, H Li, G Zhang, D Guo, C Xie, J Li, Z Yin, ... Journal of Experimental & Clinical Cancer Research 38, 1-15, 2019 | 30 | 2019 |
PAK4 phosphorylates fumarase and blocks TGFβ-induced cell growth arrest in lung cancer cells T Chen, T Wang, W Liang, Q Zhao, Q Yu, CM Ma, L Zhuo, D Guo, K Zheng, ... Cancer research 79 (7), 1383-1397, 2019 | 26 | 2019 |
Fructose-1, 6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth Z Wang, M Li, H Jiang, S Luo, F Shao, Y Xia, M Yang, X Ren, T Liu, M Yan, ... Nature cell biology 24 (11), 1655-1665, 2022 | 25 | 2022 |
Hexokinases in cancer and other pathologies D Guo, Y Meng, X Jiang, Z Lu Cell Insight 2 (1), 100077, 2023 | 20 | 2023 |
Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death D Guo, W Xie, P Xiong, H Li, S Wang, G Chen, Y Gao, J Zhou, Y Zhang, ... Cell death & disease 9 (10), 951, 2018 | 20 | 2018 |
Silencing EGFR-upregulated expression of CD55 and CD59 activates the complement system and sensitizes lung cancer to checkpoint blockade F Shao, Y Gao, W Wang, H He, L Xiao, X Geng, Y Xia, D Guo, J Fang, ... Nature Cancer 3 (10), 1192-1210, 2022 | 18 | 2022 |
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer’s disease W Xie, D Guo, J Li, L Yue, Q Kang, G Chen, T Zhou, H Wang, K Zhuang, ... Cell Death & Differentiation 29 (12), 2417-2428, 2022 | 12 | 2022 |
The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation Q Ma, H Jiang, L Ma, G Zhao, Q Xu, D Guo, N He, H Liu, Z Meng, J Liu, ... Proceedings of the National Academy of Sciences 120 (15), e2209435120, 2023 | 11 | 2023 |
Aerobic glycolysis promotes tumor immune evasion and tumor cell stemness through the noncanonical function of hexokinase 2 H He, L Xiao, J Wang, D Guo, Z Lu Cancer Communications 43 (3), 387, 2023 | 6 | 2023 |
Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic carcinoma progression Y Tong, Z Zhang, Y Cheng, J Yang, C Fan, X Zhang, J Yang, L Wang, ... Cell Death & Disease 13 (4), 413, 2022 | 6 | 2022 |
Determiners of cell fates: the tricarboxylic acid cycle versus the citrate-malate shuttle D Guo, H He, Y Meng, S Luo, Z Lu Protein & Cell 14 (3), 162-164, 2023 | 5 | 2023 |
Governing glutaminolysis by regulation of glutaminase succinylation Q Ma, H Jiang, L Ma, Y Meng, D Guo, Y Tong, Z Lu Protein & Cell 13 (3), 163-166, 2022 | 2 | 2022 |
AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth HJ Yun, M Li, D Guo, SM Jeon, SH Park, JS Lim, SB Lee, R Liu, L Du, ... Journal of Experimental & Clinical Cancer Research 42 (1), 340, 2023 | 1 | 2023 |