Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain TumorsAutophagy Inhibition in BRAFV600E Brain Tumors JMM Levy, JC Thompson, AM Griesinger, V Amani, AM Donson, DK Birks, ... Cancer discovery 4 (7), 773-780, 2014 | 249 | 2014 |
Characterization of distinct immunophenotypes across pediatric brain tumor types AM Griesinger, DK Birks, AM Donson, V Amani, LM Hoffman, A Waziri, ... The Journal of Immunology 191 (9), 4880-4888, 2013 | 233 | 2013 |
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors JM Mulcahy Levy, S Zahedi, AM Griesinger, A Morin, KD Davies, ... Elife 6, e19671, 2017 | 179 | 2017 |
Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma S Venkataraman, I Alimova, I Balakrishnan, P Harris, DK Birks, ... Oncotarget 5 (9), 2355, 2014 | 129 | 2014 |
Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells A Nellan, C Rota, R Majzner, CM Lester-McCully, AM Griesinger, ... Journal for immunotherapy of cancer 6 (1), 1-14, 2018 | 121 | 2018 |
Identification of targets for rational pharmacological therapy in childhood craniopharyngioma JM Gump, AM Donson, DK Birks, VM Amani, KK Rao, AM Griesinger, ... Acta neuropathologica communications 3 (1), 1-12, 2015 | 101 | 2015 |
Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma LM Hoffman, AM Donson, I Nakachi, AM Griesinger, DK Birks, V Amani, ... Acta neuropathologica 127, 731-745, 2014 | 89 | 2014 |
Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia B Mizukawa, J Wei, M Shrestha, M Wunderlich, FS Chou, A Griesinger, ... Blood, The Journal of the American Society of Hematology 118 (19), 5235-5245, 2011 | 83 | 2011 |
Molecular analyses reveal inflammatory mediators in the solid component and cyst fluid of human adamantinomatous craniopharyngioma AM Donson, J Apps, AM Griesinger, V Amani, DA Witt, RCE Anderson, ... Journal of Neuropathology & Experimental Neurology 76 (9), 779-788, 2017 | 76 | 2017 |
Interleukin-6/STAT3 pathway signaling drives an inflammatory phenotype in Group A ependymoma AM Griesinger, RJ Josephson, AM Donson, JM Mulcahy Levy, V Amani, ... Cancer immunology research 3 (10), 1165-1174, 2015 | 75 | 2015 |
Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma KA Riemondy, S Venkataraman, N Willard, A Nellan, B Sanford, ... Neuro-oncology 24 (2), 273-286, 2022 | 72 | 2022 |
Single-cell RNA sequencing of childhood ependymoma reveals neoplastic cell subpopulations that impact molecular classification and etiology AE Gillen, KA Riemondy, V Amani, AM Griesinger, A Gilani, ... Cell reports 32 (6), 108023, 2020 | 62 | 2020 |
The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO FS Chou, A Griesinger, M Wunderlich, S Lin, KA Link, M Shrestha, ... Blood, The Journal of the American Society of Hematology 120 (4), 709-719, 2012 | 60 | 2012 |
N-RasG12D induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene FS Chou, M Wunderlich, A Griesinger, JC Mulloy Blood, The Journal of the American Society of Hematology 117 (7), 2237-2240, 2011 | 59 | 2011 |
Inhibition of MYC attenuates tumor cell self‐renewal and promotes senescence in SMARCB1‐deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth … I Alimova, A Pierce, E Danis, A Donson, DK Birks, A Griesinger, ... International journal of cancer 144 (8), 1983-1995, 2019 | 58 | 2019 |
Specific expression of PD‐L1 in RELA‐fusion supratentorial ependymoma: Implications for PD‐1‐targeted therapy DA Witt, AM Donson, V Amani, DC Moreira, B Sanford, LM Hoffman, ... Pediatric blood & cancer 65 (5), e26960, 2018 | 46 | 2018 |
Autophagy inhibition improves chemosensitivity in BRAF (V600E) brain tumors. Cancer Discov. 2014; 4: 773–780. doi: 10.1158/2159-8290 JM Levy, JC Thompson, AM Griesinger, V Amani, AM Donson, DK Birks, ... CD-14-0049.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 38 | |
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ... Science translational medicine 13 (614), eabc0497, 2021 | 30 | 2021 |
Identification of FDA-Approved Oncology Drugs with Selective Potency in High-Risk Childhood EpendymomaEpendymoma Drug Screen AM Donson, V Amani, EA Warner, AM Griesinger, DA Witt, JMM Levy, ... Molecular cancer therapeutics 17 (9), 1984-1994, 2018 | 29 | 2018 |
Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma EW Prince, I Balakrishnan, M Shah, JMM Levy, AM Griesinger, I Alimova, ... Oncotarget 7 (33), 53881, 2016 | 28 | 2016 |