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Patrick McMullen
Patrick McMullen
Post Doctoral Fellow, Boston Children's Hospital, Koch Institute of MIT
在 mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
De novo design of functional zwitterionic biomimetic material for immunomodulation
B Li, Z Yuan, P Jain, HC Hung, Y He, X Lin, P McMullen, S Jiang
Science advances 6 (22), eaba0754, 2020
582020
Zwitterionic peptide cloak mimics protein surfaces for protein protection
Z Yuan, B Li, L Niu, C Tang, P McMullen, P Jain, Y He, S Jiang
Angewandte Chemie International Edition 59 (50), 22378-22381, 2020
472020
Enhanced pulmonary systemic delivery of protein drugs via zwitterionic polymer conjugation
C Tsao, Z Yuan, P Zhang, E Liu, P McMullen, K Wu, HC Hung, S Jiang
Journal of Controlled Release 322, 170-176, 2020
322020
Near-infrared-light-responsive lipid nanoparticles as an intelligent drug release system for cancer therapy
F Wang, Z Yuan, P McMullen, R Li, J Zheng, Y Xu, M Xu, Q He, B Li, ...
Chemistry of Materials 31 (11), 3948-3956, 2019
252019
Elucidating molecular design principles for charge-alternating peptides
J Smith, P McMullen, Z Yuan, J Pfaendtner, S Jiang
Biomacromolecules 21 (2), 435-443, 2019
182019
Zwitterionic polymer conjugated glucagon-like peptide-1 for prolonged glycemic control
C Tsao, P Zhang, Z Yuan, D Dong, K Wu, L Niu, P McMullen, S Luozhong, ...
Bioconjugate Chemistry 31 (7), 1812-1819, 2020
172020
A chromatin-mimetic nanomedicine for therapeutic tolerance induction
B Li, Z Yuan, P McMullen, J Xie, P Jain, HC Hung, S Xu, P Zhang, X Lin, ...
ACS nano 12 (12), 12004-12014, 2018
102018
Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons
W Gu, S Luozhong, S Cai, K Londhe, N Elkasri, R Hawkins, Z Yuan, ...
Nature Biomedical Engineering, 1-12, 2024
92024
A low-immunogenic genetically-fusible zwitterionic polypeptide
P McMullen, S Luozhong, C Tsao, H Xu, L Fang, S Jiang
Nano Today 47, 101674, 2022
92022
Motif-based zwitterionic peptides impact their structure and immunogenicity
P McMullen, Q Qiao, S Luozhong, L Cai, L Fang, Q Shao, S Jiang
Chemical Science 13 (36), 10961-10970, 2022
92022
Hidden hydrophobicity impacts polymer immunogenicity
Z Yuan, P McMullen, S Luozhong, P Sarker, C Tang, T Wei, S Jiang
Chemical Science 14 (8), 2033-2039, 2023
82023
Impacts of a zwitterionic peptide on its fusion protein
P McMullen, L Fang, Q Qiao, Q Shao, S Jiang
Bioconjugate Chemistry 33 (8), 1485-1493, 2022
62022
Engineered retrovirus-like nanocarriers for messenger RNA delivery into neurons
W Gu, S Luozhong, S Cai, K Londhe, N Elkasri, R Hawkins, Z Yuan, ...
22022
A De Novo Strategy To Improve Pharmacokinetics of Proteins from mRNA Therapeutics via Zwitterionic Polypeptide Fusion
S Luozhong, R Li, Z Tian, Z Cao, D Bhashyam, P Zhang, K McIlhenny, ...
Journal of the American Chemical Society, 2024
2024
Passivating the Background of Living Microbes with a Zwitterionic Peptide for Therapies
L Fang, S Cai, P McMullen, YC Hsu, MYQ Chen, S Jiang
Bioconjugate Chemistry 35 (5), 575-581, 2024
2024
Engineered retrovirus-like Arc extracellular vesicles for the in vivo targeted delivery of mRNA into the brain
W Gu, S Luozhong, K Londhe, N Elkasri, S Cai, R Hawkins, Z Yuan, ...
bioRxiv, 2022.12. 07.518870, 2022
2022
Fusion products and bioconjugates containing mixed charge peptides
C Tsao, S Luozhong, T Corrigan, S Jiang, E Liu, P McMullen
US Patent App. 17/283,708, 2021
2021
Zwitterionic Peptide Fusion Proteins for Therapeutic and Protective Applications
PJ McMullen
University of Washington, 2020
2020
Designing Superhydrophilic, Disordered Peptides to Improve the Stability and Efficacy of Protein Therapeutics
J Smith, P McMullen, Z Yuan, S Jiang, J Pfaendtner
Biophysical Journal 116 (3), 182a, 2019
2019
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