| The immunomodulatory metabolite itaconate modifies NLRP3 and inhibits inflammasome activation A Hooftman, S Angiari, S Hester, SE Corcoran, MC Runtsch, C Ling, ... Cell metabolism 32 (3), 468-478. e7, 2020 | 351 | 2020 |
| The immunomodulatory potential of the metabolite itaconate A Hooftman, LAJ O’Neill Trends in immunology 40 (8), 687-698, 2019 | 175 | 2019 |
| Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages MC Runtsch, S Angiari, A Hooftman, R Wadhwa, Y Zhang, Y Zheng, ... Cell metabolism 34 (3), 487-501. e8, 2022 | 135 | 2022 |
| Macrophage fumarate hydratase restrains mtRNA-mediated interferon production A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, ... Nature 615 (7952), 490-498, 2023 | 70 | 2023 |
| Glutathione transferase omega-1 regulates NLRP3 inflammasome activation through NEK7 deglutathionylation MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, ... Cell reports 29 (1), 151-161. e5, 2019 | 70 | 2019 |
| Caspase-11 promotes allergic airway inflammation Z Zasłona, E Flis, MM Wilk, RG Carroll, EM Palsson-McDermott, ... Nature Communications 11 (1), 1055, 2020 | 66 | 2020 |
| SARS-CoV-2 targets MAVS for immune evasion A Zotta, A Hooftman, LAJ O’Neill Nature Cell Biology 23 (7), 682-683, 2021 | 19 | 2021 |
| Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, ECO Brien, ... Nature Communications 14 (1), 3513, 2023 | 17 | 2023 |
| Nanoparticle asymmetry shapes an immune response A Hooftman, LAJ O’Neill Nature 601 (7893), 323-325, 2022 | 10 | 2022 |
| Can NLRP3 inhibitors improve on dexamethasone for the treatment of COVID-19? A Hooftman, LAJ O'Neill Current Research in Pharmacology and Drug Discovery 2, 100048, 2021 | 5 | 2021 |
| Basic mechanisms of Immunometabolites in shaping the immune response DG Ryan, CG Peace, A Hooftman Journal of Innate Immunity 15 (1), 925-943, 2023 | 2 | 2023 |
| Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, EC O’Brien, ... nature communications 14, 2023 | 1 | 2023 |
| Therapeutic opportunities targeting the NLRP3 inflammasome A Hooftman, A Zotta, LAJ O'Neill Inflammasome Biology, 555-563, 2023 | 1 | 2023 |
| OC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon T Ryan, A Hooftman, A Rehill, M Johansen, E O’Brien, J Toller-Kawahisa, ... Research and Practice in Thrombosis and Haemostasis 7, 100502, 2023 | | 2023 |
| Inflammatory mitochondrial nucleic acids as drivers of pathophysiology CG Peace, A Hooftman, DG Ryan Clinical and Translational Medicine 13 (9), 2023 | | 2023 |
| Targeting fumarate hydratase promotes mitochondrial RNA-mediated interferon production A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, ... Nature 615 (7952), 490, 2023 | | 2023 |
| Basic Mechanisms of Immunometabolites in Shaping the Immune DG Ryan, CG Peace, A Hooftman | | 2023 |
| The Immunomodulatory Metabolite Itaconate Regulates NLRP3 Inflammasome Activation and Type I Interferon Signalling A Hooftman Trinity College Dublin, 2021 | | 2021 |
