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Thomas K. Karikari
Thomas K. Karikari
在 pitt.edu 的电子邮件经过验证 - 首页
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Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts
TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ...
The Lancet Neurology 19 (5), 422-433, 2020
8952020
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology
NJ Ashton, TA Pascoal, TK Karikari, AL Benedet, J Lantero-Rodriguez, ...
Acta neuropathologica 141, 709-724, 2021
4002021
Microglial activation and tau propagate jointly across Braak stages
TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ...
Nature medicine 27 (9), 1592-1599, 2021
3242021
A multicentre validation study of the diagnostic value of plasma neurofilament light
NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ...
Nature communications 12 (1), 3400, 2021
2982021
Plasma p-tau181 accurately predicts Alzheimer’s disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline
J Lantero Rodriguez, TK Karikari, M Suárez-Calvet, C Troakes, A King, ...
Acta neuropathologica 140, 267-278, 2020
2612020
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum
AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ...
JAMA neurology 78 (12), 1471-1483, 2021
2592021
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ …
M Suárez‐Calvet, TK Karikari, NJ Ashton, J Lantero Rodriguez, ...
EMBO molecular medicine 12 (12), e12921, 2020
2562020
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative
TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ...
Molecular psychiatry 26 (2), 429-442, 2021
2482021
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease
J Simrén, A Leuzy, TK Karikari, A Hye, AL Benedet, J Lantero‐Rodriguez, ...
Alzheimer's & Dementia 17 (7), 1145-1156, 2021
2192021
Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease
M Milà-Alomà, NJ Ashton, M Shekari, G Salvadó, P Ortiz-Romero, ...
Nature Medicine 28 (9), 1797-1801, 2022
2102022
Longitudinal associations of blood phosphorylated Tau181 and neurofilament light chain with neurodegeneration in Alzheimer disease
A Moscoso, MJ Grothe, NJ Ashton, TK Karikari, JL Rodríguez, A Snellman, ...
JAMA neurology 78 (4), 396-406, 2021
1902021
Time course of phosphorylated-tau181 in blood across the Alzheimer’s disease spectrum
A Moscoso, MJ Grothe, NJ Ashton, TK Karikari, JL Rodriguez, A Snellman, ...
Brain 144 (1), 325-339, 2021
1722021
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring
NJ Ashton, S Janelidze, N Mattsson-Carlgren, AP Binette, O Strandberg, ...
Nature medicine 28 (12), 2555-2562, 2022
1652022
An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders
NJ Ashton, A Hye, AP Rajkumar, A Leuzy, S Snowden, M Suárez-Calvet, ...
Nature Reviews Neurology 16 (5), 265-284, 2020
1592020
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility
TK Karikari, NJ Ashton, G Brinkmalm, WS Brum, AL Benedet, ...
Nature Reviews Neurology 18 (7), 400-418, 2022
1452022
Comparison of plasma phosphorylated tau species with amyloid and tau positron emission tomography, neurodegeneration, vascular pathology, and cognitive outcomes
MM Mielke, RD Frank, JL Dage, A Jeromin, NJ Ashton, K Blennow, ...
JAMA neurology 78 (9), 1108-1117, 2021
1452021
Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar degeneration
A Benussi, TK Karikari, N Ashton, S Gazzina, E Premi, L Benussi, ...
Journal of Neurology, Neurosurgery & Psychiatry 91 (9), 960-967, 2020
1272020
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging
J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ...
Nature aging 2 (6), 526-535, 2022
1232022
Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease
P Chatterjee, S Pedrini, NJ Ashton, M Tegg, K Goozee, AK Singh, ...
Alzheimer's & Dementia 18 (6), 1141-1154, 2022
1202022
Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change
DS Smirnov, NJ Ashton, K Blennow, H Zetterberg, J Simrén, ...
Acta neuropathologica 143 (4), 487-503, 2022
1202022
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