N‐acetylcysteine attenuates the decline in muscle Na+,K+‐pump activity and delays fatigue during prolonged exercise in humans MJ McKenna, I Medved, CA Goodman, MJ Brown, AR Bjorksten, ... The Journal of physiology 576 (1), 279-288, 2006 | 317 | 2006 |
N-acetylcysteine enhances muscle cysteine and glutathione availability and attenuates fatigue during prolonged exercise in endurance-trained individuals I Medved, MJ Brown, AR Bjorksten, KT Murphy, AC Petersen, S Sostaric, ... Journal of Applied Physiology, 2004 | 303 | 2004 |
Elevated expression of activins promotes muscle wasting and cachexia JL Chen, KL Walton, CE Winbanks, KT Murphy, RE Thomson, Y Makanji, ... The FASEB Journal 28 (4), 1711-1723, 2014 | 220 | 2014 |
Disease-induced skeletal muscle atrophy and fatigue SK Powers, GS Lynch, KT Murphy, MB Reid, I Zijdewind Medicine and science in sports and exercise 48 (11), 2307, 2016 | 211 | 2016 |
Intensified exercise training does not alter AMPK signaling in human skeletal muscle SA Clark, ZP Chen, KT Murphy, RJ Aughey, MJ McKenna, BE Kemp, ... American Journal of Physiology-Endocrinology and Metabolism 286 (5), E737-E743, 2004 | 185 | 2004 |
Antibody‐directed myostatin inhibition in 21‐mo‐old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function KT Murphy, R Koopman, T Naim, B Léger, J Trieu, C Ibebunjo, GS Lynch The FASEB Journal 24 (11), 4433-4442, 2010 | 148 | 2010 |
Targeting of Fn14 prevents cancer-induced cachexia and prolongs survival AJ Johnston, KT Murphy, L Jenkinson, D Laine, K Emmrich, P Faou, ... Cell 162 (6), 1365-1378, 2015 | 145 | 2015 |
Importance of functional and metabolic impairments in the characterization of the C-26 murine model of cancer cachexia KT Murphy, A Chee, J Trieu, T Naim, GS Lynch Disease models & mechanisms 5 (4), 533-545, 2012 | 142 | 2012 |
Antibody-directed myostatin inhibition enhances muscle mass and function in tumor-bearing mice KT Murphy, A Chee, BG Gleeson, T Naim, K Swiderski, R Koopman, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011 | 132 | 2011 |
The pathogenesis and treatment of cardiac atrophy in cancer cachexia KT Murphy American Journal of Physiology-Heart and Circulatory Physiology 310 (4 …, 2016 | 120 | 2016 |
Infusion with the antioxidant N‐acetylcysteine attenuates early adaptive responses to exercise in human skeletal muscle AC Petersen, MJ McKenna, I Medved, KT Murphy, MJ Brown, ... Acta physiologica 204 (3), 382-392, 2012 | 118 | 2012 |
Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia DJ Ham, KT Murphy, A Chee, GS Lynch, R Koopman Clinical nutrition 33 (3), 448-458, 2014 | 113 | 2014 |
Exercise performance falls over time in patients with chronic kidney disease despite maintenance of hemoglobin concentration MJ Leikis, MJ McKenna, AC Petersen, AB Kent, KT Murphy, JA Leppik, ... Clinical Journal of the American Society of Nephrology 1 (3), 488-495, 2006 | 98 | 2006 |
Cellular mechanisms underlying temporal changes in skeletal muscle protein synthesis and breakdown during chronic β‐adrenoceptor stimulation in mice R Koopman, SM Gehrig, B Léger, J Trieu, S Walrand, KT Murphy, ... The Journal of physiology 588 (23), 4811-4823, 2010 | 94 | 2010 |
Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes RJ Aughey, KT Murphy, SA Clark, AP Garnham, RJ Snow, ... Journal of applied physiology 103 (1), 39-47, 2007 | 87 | 2007 |
Intense exercise up‐regulates Na+,K+‐ATPase isoform mRNA, but not protein expression in human skeletal muscle KT Murphy, RJ Snow, AC Petersen, RM Murphy, J Mollica, JS Lee, ... The Journal of physiology 556 (2), 507-519, 2004 | 86 | 2004 |
Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice CE Winbanks, KT Murphy, BC Bernardo, H Qian, Y Liu, PV Sepulveda, ... Science translational medicine 8 (348), 348ra98-348ra98, 2016 | 85 | 2016 |
Antibody-directed myostatin inhibition improves diaphragm pathology in young but not adult dystrophic mdx mice KT Murphy, JG Ryall, SM Snell, L Nair, R Koopman, PA Krasney, ... The American journal of pathology 176 (5), 2425-2434, 2010 | 73 | 2010 |
Depressed Na+-K+-ATPase activity in skeletal muscle at fatigue is correlated with increased Na+-K+-ATPase mRNA expression following intense exercise AC Petersen, KT Murphy, RJ Snow, JA Leppik, RJ Aughey, AP Garnham, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005 | 73 | 2005 |
Update on emerging drugs for cancer cachexia KT Murphy, GS Lynch Expert Opinion on Emerging Drugs 14 (4), 619-632, 2009 | 64 | 2009 |