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Blake T Riley
Blake T Riley
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Modelling of thyroid peroxidase reveals insights into its enzyme function and autoantigenicity
SN Le, BT Porebski, J McCoey, J Fodor, B Riley, M Godlewska, M Gora, ...
PloS one 10 (12), e0142615, 2015
562015
Reactive centre loop dynamics and serpin specificity
EM Marijanovic, J Fodor, BT Riley, BT Porebski, MGS Costa, I Kass, ...
Scientific Reports 9 (1), 3870, 2019
382019
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
BT Riley, O Ilyichova, MGS Costa, BT Porebski, SJ de Veer, JE Swedberg, ...
Scientific Reports 6, 35385, 2016
372016
qFit 3: Protein and ligand multiconformer modeling for X‐ray crystallographic and single‐particle cryo‐EM density maps
BT Riley, SA Wankowicz, SHP de Oliveira, GCP van Zundert, DW Hogan, ...
Protein Science 30 (1), 270-285, 2021
362021
Previously Hidden Dynamics at the TCR–Peptide–MHC Interface Revealed
J Fodor, BT Riley, NA Borg, AM Buckle
The Journal of Immunology 200 (12), 4134-4145, 2018
362018
Strategies for increasing protein stability
PG Chandler, SS Broendum, BT Riley, MA Spence, CJ Jackson, ...
Protein Nanotechnology: Protocols, Instrumentation, and Applications, 163-181, 2020
262020
The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro)
A Ebrahim, BT Riley, D Kumaran, B Andi, MR Fuchs, S McSweeney, ...
IUCrJ 9 (5), 682-694, 2022
242022
Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases
W Yang, BT Riley, X Lei, BT Porebski, I Kass, AM Buckle, S McGowan
Journal of Biomolecular Structure and Dynamics 36 (10), 2595-2604, 2018
152018
Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif
X Chen, BT Riley, SJ De Veer, DE Hoke, J Van Haeften, D Leahy, ...
PloS one 14 (1), e0210842, 2019
142019
The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro)
A Ebrahim, BT Riley, D Kumaran, B Andi, MR Fuchs, S McSweeney, ...
bioRxiv, 2021
132021
KLK4 inhibition by cyclic and acyclic peptides: structural and dynamical insights into standard-mechanism protease inhibitors
BT Riley, O Ilyichova, SJ De Veer, JE Swedberg, E Wilson, DE Hoke, ...
Biochemistry 58 (21), 2524-2533, 2019
132019
Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments
J Islam, BT Riley, C Fercher, ML Jones, AM Buckle, CB Howard, RP Cox, ...
Analytical chemistry 91 (12), 7631-7638, 2019
122019
Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA‐M1
W Yang, BT Riley, X Lei, BT Porebski, I Kass, AM Buckle, S McGowan
ChemMedChem 13 (23), 2504-2513, 2018
112018
Mutational and biophysical robustness in a prestabilized monobody
PG Chandler, LL Tan, BT Porebski, JS Green, BT Riley, SS Broendum, ...
Journal of Biological Chemistry 296, 100447, 2021
82021
Uncovering protein ensembles: automated multiconformer model building for X-ray crystallography and cryo-EM
SA Wankowicz, A Ravikumar, S Sharma, BT Riley, A Raju, J Flowers, ...
bioRxiv, 2023
72023
The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome
J Fodor, BT Riley, I Kass, AM Buckle, NA Borg
Scientific Reports 9 (1), 10523, 2019
72019
Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC
BT Riley, SS Broendum, CF Reboul, NP Cowieson, MGS Costa, I Kass, ...
PloS one 10 (10), e0140219, 2015
72015
Pushed to extremes: distinct effects of high temperature versus pressure on the structure of STEP
L Guerrero, A Ebrahim, BT Riley, M Kim, Q Huang, AD Finke, DA Keedy
Communications Biology 7 (1), 59, 2024
22024
Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase
L Guerrero, A Ebrahim, BT Riley, M Kim, Q Huang, AD Finke, DA Keedy
bioRxiv, 2023.05. 02.538097, 2023
22023
A metal ion–dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase
CT Webb, W Yang, BT Riley, BK Hayes, KK Sivaraman, TR Malcolm, ...
Journal of Biological Chemistry 298 (7), 2022
22022
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