Next-generation characterization of the cancer cell line encyclopedia M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ... Nature 569 (7757), 503-508, 2019 | 2807 | 2019 |
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ... Nature communications 10 (1), 1617, 2019 | 692 | 2019 |
Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis Y Zou, H Li, ET Graham, AA Deik, JK Eaton, W Wang, G Sandoval-Gomez, ... Nature chemical biology 16 (3), 302-309, 2020 | 571 | 2020 |
The landscape of cancer cell line metabolism H Li, S Ning, M Ghandi, GV Kryukov, S Gopal, A Deik, A Souza, K Pierce, ... Nature medicine 25 (5), 850-860, 2019 | 455 | 2019 |
Metabolomic adaptations and correlates of survival to immune checkpoint blockade H Li, K Bullock, C Gurjao, D Braun, SA Shukla, D Bossé, AKA Lalani, ... Nature communications 10 (1), 1-6, 2019 | 211 | 2019 |
Proteomic discovery of chemical probes that perturb protein complexes in human cells MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ... Molecular cell 83 (10), 1725-1742. e12, 2023 | 55 | 2023 |
Remodeling oncogenic transcriptomes by small molecules targeting NONO SG Kathman, SJ Koo, GL Lindsey, HL Her, SM Blue, H Li, S Jaensch, ... Nature chemical biology 19 (7), 825-836, 2023 | 38 | 2023 |
TMEM164 is an acyltransferase that forms ferroptotic C20: 4 ether phospholipids A Reed, T Ware, H Li, J Fernando Bazan, BF Cravatt Nature chemical biology 19 (3), 378-388, 2023 | 34 | 2023 |
Assigning functionality to cysteines by base editing of cancer dependency genes H Li, T Ma, JR Remsberg, SJ Won, KE DeMeester, E Njomen, ... Nature chemical biology 19 (11), 1320-1330, 2023 | 29 | 2023 |
6-Phosphogluconate dehydrogenase links cytosolic carbohydrate metabolism to protein secretion via modulation of glutathione levels H Li, M Ericsson, B Rabasha, B Budnik, SH Chan, E Freinkman, CA Lewis, ... Cell chemical biology 26 (9), 1306-1314. e5, 2019 | 25 | 2019 |
Phospholipase Cγ2 regulates endocannabinoid and eicosanoid networks in innate immune cells H Jing, A Reed, OA Ulanovskaya, JS Grigoleit, DM Herbst, CL Henry, H Li, ... Proceedings of the National Academy of Sciences 118 (41), e2112971118, 2021 | 21 | 2021 |
Metabolomic correlates of response in nivolumab-treated renal cell carcinoma and melanoma patients. M Giannakis, H Li, C Jin, S Gopal, K Desai, C Horak, M Wind-Rotolo, ... Journal of Clinical Oncology 35 (15_suppl), 3036-3036, 2017 | 18 | 2017 |
SPIN4 is a principal endogenous substrate of the E3 ubiquitin ligase DCAF16 X Zhang, M Thielert, H Li, BF Cravatt Biochemistry 60 (9), 637-642, 2021 | 15 | 2021 |
HIF-2α drives an intrinsic vulnerability to ferroptosis in clear cell renal cell carcinoma Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ... BioRxiv, 388041, 2018 | 10 | 2018 |